By Nelson Vergel | ExcelMale.com | Updated December 2025 Summary: This comprehensive guide examines the development of FDA-approved oral testosterone products—Jatenzo, Tlando, and Kyzatrex—which overcome the liver toxicity problems of earlier...
Summary: The TRAVERSE trial, a landmark FDA-mandated study involving over 5,200 men, has definitively concluded that testosterone replacement therapy (TRT) does not increase the risk of major cardiovascular events like heart attacks, strokes, or...
SUMMARY: This comprehensive article examines the combination of testosterone replacement therapy (TRT) with GLP-1 medications like semaglutide and tirzepatide for men managing both low testosterone and obesity or type 2 diabetes. Research...
This nationwide study examines the prevalence of testosterone deficiency and the subsequent use of replacement therapy among men living with HIV. By analyzing data from over 100 million patients, researchers discovered that healthcare providers...
Learn how clascoterone works, clinical uses for hair loss and acne, dosing basics, and safety considerations. Clascoterone 5% Topical Solution for Male Androgenetic Alopecia Overview Clascoterone 5% topical solution represents what could be the...
How Much Testosterone Are You Actually Getting From Your TRT Protocol? If you're on testosterone replacement therapy (TRT), you've probably used a steroid calculator or plotter to visualize your dosing protocol. But here's a critical question...
FDA Approval of Testosterone Therapy for Women: An Analysis of Historical Failures, Regulatory Hurdles, and a Path Forward Executive Summary The landscape of testosterone therapy presents a stark gender disparity: while over 31 FDA-approved...
Melatonin's Role in Reproductive Health and Fertility Executive Summary Melatonin (N-acetyl-5-methoxytryptamine), a neurohormone primarily known for regulating circadian rhythms, demonstrates profound and multifaceted effects on male and female...
I collected questions and answers posted on ExcelMale.com in the last 10 years about the use of human chorionic gonadotropin in men who want to prevent loss of testicular size and fertility while on testosterone replacement therapy or that want...
Starting a family with a partner that you love is one of the most magical and exciting experiences that you will ever encounter. It is also daunting and very intimidating, but ultimately, becoming a parent will change you for the better. Sadly...
Practical Clinical Summary on Testosterone Therapy in Women (From ExcelMale.com) Based on the ExcelMale forum threads and related clinical literature, here's a comprehensive extraction of practical content for a clinical article: Physiological...
Can testosterone and anabolic agents reverse muscle wasting? This is the story of how hormone therapy transformed HIV treatment—and what it means for men's health today. Nelson Vergel was diagnosed HIV-positive in 1985 when it was a death...
