Testosterone a Hormone for Health and Survival in Men

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* He presents compelling data showing that Testosterone Replacement Therapy (TRT), when bringing levels back to the normal range, can significantly reduce all-cause and cardiovascular death rates, improve quality of life, reduce insulin resistance (the core defect in diabetes), and even improve cognitive function, advocating for its wider adoption in clinical practice as a "health hormone."





Hugh Jones's presentation at the Longevity Forum Science Summit delves into the strong, often overlooked, association between low testosterone in men and increased cardiovascular mortality and chronic health issues. Drawing on research from Sheffield and other international studies, Dr. Jones highlights that low testosterone is not simply an aging factor but is highly correlated with functional hypogonadism caused by co-morbidities like Type 2 diabetes, obesity, and metabolic syndrome. He presents compelling data showing that Testosterone Replacement Therapy (TRT), when bringing levels back to the normal range, can significantly reduce all-cause and cardiovascular death rates, improve quality of life, reduce insulin resistance (the core defect in diabetes), and even improve cognitive function, advocating for its wider adoption in clinical practice as a "health hormone."




















 
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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