Tadalafil (Cialis) minimum effective dose...

[Sergel]

Excuse my enthusiasm, I just had my first Cialis experience... I am like a kid this morning... darn...

TLDR: I only took 2 to 2.5 mg of Cialis at 1pm, made love at 11pm and had a hell of a stiffie and great orgasm... Any one else get by with such a small dose...

Now the full story:

But, darn, such a small dose being so efficient? On trt (100 mg / week, 50mg e3.5d, enanthate) I feel real good. Low SHBG makes my free T high at that dose... so with T I had to learn the hard way that less is better for me... I have good morning wood most mornings, am 63 ...

Now in discussing erection with my doc, he suggested Cialis... at 63, I though maybe it was time... although I could have an erection during intercourse, the quality or durability of it often fell short (excuse the pun)... many times I could not get to climax, I would start with a stiffie, play... it would go away, come back, go away, come back... and had a terrible time climaxing... like I was anorgasmic... quite frustrating.

So he suggested 20mg on demand... but having read here a lot about Tadalafil, I asked him to give me the 5mg variety so I could modulate... and try daily ... basically I like to experiment. But being allergic to quite a few things, I wanted to try out a small dose (I took the small half of a 5mg split in two)... question to see if the congestion, headaches and all those aweful things they plaster all over the internet would show their heads.... I did not expect anything from such a small dose (probably between 2 and 2.5 mg... !)

So my girlfriend came to dinner, I had no boose... (I like wine a lot...) ... and we went to bed...Oh boy... My girlfriend was not in on the secret yet... lol We were basically just kissing and she said, oh! Look at this! ... I was as surprized as her...

Damn, I did not have an erection like that in my 20s ... It lasted from arousal to orgasm...like I was 20 again! Holy moly Batman... that was something... and the orgasm was so intense, sensitivity was good... damn... Again, excuse my enthusiasm... Tadalafil newbie here...

My question is: ... Am I hyper sensitive to this thing? Are other guys getting good effect from such a small dose? Will I build a resistance? Anyone else using 2.5mg on demand and getting results?

 

[Golfboy307]

There might be a bit of the placebo factor at play. That is a really low dose to have that dramatic effect. But, hey, its the result that counts! If you really do respond that well, PDE-5 inhibitors will be great to have in your arsenal. The lower the better so their effectiveness won't wane. I take 2.5 -3mg daily with generally good results. But it doesn't work on demand for me like that. (Viagra does..)

 

[Sergel]

That's what I thought too... I was not expecting anything... but it was surnatural... if it's placebo, I need to find the place in my head where I was... but I was thinking of 2.5 daily... I will continue to experiment, but even morning wood this morning was a little persistant... I was just surprized by my response...

I am fully opened to the possibility that it was all in my head... but somehow think it was too much to be natural... at least unseen since my 20s

 

[forumjoe]

2.5 works well for me

 

[Sergel]

2.5 works well for me

Oh, I am happy to see I am not the only one... Thanks...

 

[Sergel]

Wow, I found the reviews on Drugs.com ... for Cialis... Seems like many are like me, one 2.5mg the get hard for a couple of days... So I guess I am not that special! ... lol A lot of enthusiasm in those reviews... really a wonder pill, I am truly flabergasted.

Cialis for Erectile Dysfunction Reviews - Drugs.com

Reviews and ratings for Cialis when used in the treatment of erectile dysfunction. 457 reviews submitted with a 8.6 average score.

www.drugs.com

 

[madman]

Excuse my enthusiasm, I just had my first Cialis experience... I am like a kid this morning... darn...

TLDR: I only took 2 to 2.5 mg of Cialis at 1pm, made love at 11pm and had a hell of a stiffie and great orgasm... Any one else get by with such a small dose...

Now the full story:

But, darn, such a small dose being so efficient? On trt (100 mg / week, 50mg e3.5d, enanthate) I feel real good. Low SHBG makes my free T high at that dose... so with T I had to learn the hard way that less is better for me... I have good morning wood most mornings, am 63 ...

Now in discussing erection with my doc, he suggested Cialis... at 63, I though maybe it was time... although I could have an erection during intercourse, the quality or durability of it often fell short (excuse the pun)... many times I could not get to climax, I would start with a stiffie, play... it would go away, come back, go away, come back... and had a terrible time climaxing... like I was anorgasmic... quite frustrating.

So he suggested 20mg on demand... but having read here a lot about Tadalafil, I asked him to give me the 5mg variety so I could modulate... and try daily ... basically I like to experiment. But being allergic to quite a few things, I wanted to try out a small dose (I took the small half of a 5mg split in two)... question to see if the congestion, headaches and all those aweful things they plaster all over the internet would show their heads.... I did not expect anything from such a small dose (probably between 2 and 2.5 mg... !)

So my girlfriend came to dinner, I had no boose... (I like wine a lot...) ... and we went to bed...Oh boy... My girlfriend was not in on the secret yet... lol We were basically just kissing and she said, oh! Look at this! ... I was as surprized as her...

Damn, I did not have an erection like that in my 20s ... It lasted from arousal to orgasm...like I was 20 again! Holy moly Batman... that was something... and the orgasm was so intense, sensitivity was good... damn... Again, excuse my enthusiasm... Tadalafil newbie here...

My question is: ... Am I hyper sensitive to this thing? Are other guys getting good effect from such a small dose? Will I build a resistance? Anyone else using 2.5mg on demand and getting results?

Of course, you can!

Although most would look at sildenafil as the on-demand pde5i believe it or not when taking tadalafil blood levels will reach the Tmax 0.8-1.2 hrs after you take it.

Top it off that the effects can last for 36 hrs.

Daily is the way to go and you will notice stronger/firmer/longer-lasting erections when erect and the penis will be fuller/plumper when flaccid let alone sensitivity/orgasms will increase due to improved blood flow and top it off that you will notice an increase in the quality of erections achieved during sleep NPT (nocturnal penile tumescence).

When you wake up in the middle of the night during NPT you will know what I mean.

Ones underlying vascular health will play a strong role in how well you respond to a said dose.

2.5-5 mg is the dose used when taking daily.

Many are using 5 mg/day but others may experience the beneficial effects when using a dose on the lower end of 2.5 mg/day.

Long-term treatment of ED: beyond the purely symptomatic use of PDE5I

Thinking About Pathomechanisms and Current Treatment of Erectile Dysfunction—“The Stanley Beamish Problem.” Review, Recommendations, and Proposals ABSTRACT Introduction: Up to 50% of all men over 50 years of age suffer from erectile dysfunction. Since the late 1990s erectile dysfunction has...

www.excelmale.com

PDE5i: Structure-function regulation and therapeutic applications of inhibitors

Phosphodiesterase 5 (PDE5): Structure-function regulation and therapeutic applications of inhibitors ABSTRACT Phosphodiesterase 5 (PDE5) is one of the most well-studied phosphodiesterases (PDEs) that specifically targets cGMP typically generated by nitric oxide (NO)-mediated activation of the...

www.excelmale.com

Efficacy of TRT plus alternate-day tadalafil for patients with LOH

Efficacy of testosterone replacement therapy plus alternate-day tadalafil for patients with late-onset hypogonadism: An open-label, a randomized, crossover study Objective: To examine the efficacy and safety of combination treatment with testosterone replacement therapy plus alternate-day...

www.excelmale.com

PDE5i ED Drugs are beneficial to the heart

Do phosphodiesterase-5 inhibitors have a cardioprotective effect? Fernando Nestor Facio Junior Erectile dysfunction (ED) affects 18 million men in the United States alone1. Its prevalence is 52% among men aged from 40 to 70 years and 70% among those older than 702. This condition may be...

www.excelmale.com

Age related ED: How to Prevent it and Manage it

Looking at some of the more recent studies it has been stated that: *No evidence has emerged concerning the development of any form of dependence or tolerance with the chronic use of PDE5 inhibitors. Aging-related erectile dysfunction—a potential mechanism to halt or delay its onset Monica...

www.excelmale.com

does PDE5 inhibitors downregulate NO production?

I'm considering to start a daily or most days or the week 5mg Tadalafil to help in reversing Peyronies diseases (PD), I don't have any erection issues, but to my understanding it is really important to have a "solid" erection during sex not to worsen PD. I'm 34 years old now, and I'm wondering...

www.excelmale.com

Prescribing pharmacotherapy for the treatment of ED

Considerations for Prescribing Pharmacotherapy for the Treatment of Erectile Dysfunction Ahmed M. Bakr, Amro A. El-Sakka & Ahmed I. El-Sakka Abstract: Introduction: The effectiveness of phosphodiesterase type 5 inhibitors (PDE5i) in treating erectile dysfunction (ED) creates a new field...

www.excelmale.com

Beyond ED: Emerging indications of sildenafil

Sildenafil Beyond Erectile Dysfunction and Pulmonary Arterial Hypertension: Thinking About New Indications Moein Ala, Razieh Mohammad Jafari, Ahmad Reza Dehpour ABSTRACT Sildenafil, approved two decades ago, is the inhibitor of Phosphodiesterase 5 (PDE5). First of all, it was designated...

www.excelmale.com

Are erections on tadalafil normal while we sleep?

I know that Tadalafil is not meant to give you an erection without arousal but is it a typical side effect to have erections during the night even though you are sleeping alone and not aroused?

www.excelmale.com

The Use of Vasoactive Drugs in the Treatment of ED

Abstract: It is widely accepted that disorders of the male (uro) genital tract, such as erectile dysfunction (ED) and benign diseases of the prostate (lower urinary tract symptomatology or benign prostatic hyperplasia), can be approached therapeutically by influencing the function of both the...

www.excelmale.com

daily use of L-arginine, tadalafil and combined L-arginine with tadalafil in the treatment of elderly patients with ED

Comparison of the clinical efficacy of daily use of L-arginine, tadalafil and combined L-arginine with tadalafil in the treatment of elderly patients with erectile dysfunction. Abstract This study aimed to evaluate the efficacy of the daily oral administrations of L-arginine, tadalafil and...

www.excelmale.com

Endothelial Dysfunction in Patients With Erectile Dysfunction: A Double-Blind, Randomized-Control Trial Using Tadalafil

Objective: To assess whether tadalafil improves endothelial dysfunction(EnD) in a placebo-controlled randomized-control trial. Methods: Erectile dysfunction and EnD were assessed by the International Index of Erectile Function (IIEF-5) and flow-mediated dilation (FMD) of the brachial artery...

www.excelmale.com

Pharmacodynamics of the agents used for the treatment of erectile dysfunction

ABSTRACT Introduction: Erectile dysfunction (ED) is one of the most common complaints encountered by the practicing urologist, particularly when treating older men. The last 20 years have represented a pivotal time in the treatment of ED. Areas covered: Several pharmacologic agents have been...

www.excelmale.com

Tadalafil: 15 years' journey in male erectile dysfunction and beyond

Abstract Tadalafil, Cialis, Eli Lilly & Co./ICOS, (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12ahexahydropyrazino[10,20:1,6] pyrido[3,4-b]indole-1,4-dione, was first discovered in 2003. It was reported to have high diastereospecificity for phosphodiesterase 5 (PDE5) inhibitions...

www.excelmale.com

 

[Sergel]

Of course, you can!

Although most would look at sildenafil as the on-demand pde5i believe it or not when taking tadalafil blood levels will reach the Tmax 0.8-1.2 hrs after you take it.

Top it off that the effects can last for 36 hrs.

Daily is the way to go and you will notice stronger/firmer/longer-lasting erections when erect and the penis will be fuller/plumper when flaccid let alone sensitivity/orgasms will increase due to improved blood flow and top it off that you will notice an increase in the quality of erections achieved during sleep NPT (nocturnal penile tumescence).

When you wake up in the middle of the night during NPT you will know what I mean.

Ones underlying vascular health will play a strong role in how well you respond to a said dose.

2.5-5 mg is the dose used when taking daily.

Many are using 5 mg/day but others may experience the beneficial effects when using a dose on the lower end of 2.5 mg/day.

Long-term treatment of ED: beyond the purely symptomatic use of PDE5I

Thinking About Pathomechanisms and Current Treatment of Erectile Dysfunction—“The Stanley Beamish Problem.” Review, Recommendations, and Proposals ABSTRACT Introduction: Up to 50% of all men over 50 years of age suffer from erectile dysfunction. Since the late 1990s erectile dysfunction has...

www.excelmale.com

PDE5i: Structure-function regulation and therapeutic applications of inhibitors

Phosphodiesterase 5 (PDE5): Structure-function regulation and therapeutic applications of inhibitors ABSTRACT Phosphodiesterase 5 (PDE5) is one of the most well-studied phosphodiesterases (PDEs) that specifically targets cGMP typically generated by nitric oxide (NO)-mediated activation of the...

www.excelmale.com

Efficacy of TRT plus alternate-day tadalafil for patients with LOH

Efficacy of testosterone replacement therapy plus alternate-day tadalafil for patients with late-onset hypogonadism: An open-label, a randomized, crossover study Objective: To examine the efficacy and safety of combination treatment with testosterone replacement therapy plus alternate-day...

www.excelmale.com

PDE5i ED Drugs are beneficial to the heart

Do phosphodiesterase-5 inhibitors have a cardioprotective effect? Fernando Nestor Facio Junior Erectile dysfunction (ED) affects 18 million men in the United States alone1. Its prevalence is 52% among men aged from 40 to 70 years and 70% among those older than 702. This condition may be...

www.excelmale.com

Age related ED: How to Prevent it and Manage it

Looking at some of the more recent studies it has been stated that: *No evidence has emerged concerning the development of any form of dependence or tolerance with the chronic use of PDE5 inhibitors. Aging-related erectile dysfunction—a potential mechanism to halt or delay its onset Monica...

www.excelmale.com

does PDE5 inhibitors downregulate NO production?

I'm considering to start a daily or most days or the week 5mg Tadalafil to help in reversing Peyronies diseases (PD), I don't have any erection issues, but to my understanding it is really important to have a "solid" erection during sex not to worsen PD. I'm 34 years old now, and I'm wondering...

www.excelmale.com

Prescribing pharmacotherapy for the treatment of ED

Considerations for Prescribing Pharmacotherapy for the Treatment of Erectile Dysfunction Ahmed M. Bakr, Amro A. El-Sakka & Ahmed I. El-Sakka Abstract: Introduction: The effectiveness of phosphodiesterase type 5 inhibitors (PDE5i) in treating erectile dysfunction (ED) creates a new field...

www.excelmale.com

Beyond ED: Emerging indications of sildenafil

Sildenafil Beyond Erectile Dysfunction and Pulmonary Arterial Hypertension: Thinking About New Indications Moein Ala, Razieh Mohammad Jafari, Ahmad Reza Dehpour ABSTRACT Sildenafil, approved two decades ago, is the inhibitor of Phosphodiesterase 5 (PDE5). First of all, it was designated...

www.excelmale.com

Are erections on tadalafil normal while we sleep?

I know that Tadalafil is not meant to give you an erection without arousal but is it a typical side effect to have erections during the night even though you are sleeping alone and not aroused?

www.excelmale.com

The Use of Vasoactive Drugs in the Treatment of ED

Abstract: It is widely accepted that disorders of the male (uro) genital tract, such as erectile dysfunction (ED) and benign diseases of the prostate (lower urinary tract symptomatology or benign prostatic hyperplasia), can be approached therapeutically by influencing the function of both the...

www.excelmale.com

daily use of L-arginine, tadalafil and combined L-arginine with tadalafil in the treatment of elderly patients with ED

Comparison of the clinical efficacy of daily use of L-arginine, tadalafil and combined L-arginine with tadalafil in the treatment of elderly patients with erectile dysfunction. Abstract This study aimed to evaluate the efficacy of the daily oral administrations of L-arginine, tadalafil and...

www.excelmale.com

Endothelial Dysfunction in Patients With Erectile Dysfunction: A Double-Blind, Randomized-Control Trial Using Tadalafil

Objective: To assess whether tadalafil improves endothelial dysfunction(EnD) in a placebo-controlled randomized-control trial. Methods: Erectile dysfunction and EnD were assessed by the International Index of Erectile Function (IIEF-5) and flow-mediated dilation (FMD) of the brachial artery...

www.excelmale.com

Pharmacodynamics of the agents used for the treatment of erectile dysfunction

ABSTRACT Introduction: Erectile dysfunction (ED) is one of the most common complaints encountered by the practicing urologist, particularly when treating older men. The last 20 years have represented a pivotal time in the treatment of ED. Areas covered: Several pharmacologic agents have been...

www.excelmale.com

Tadalafil: 15 years' journey in male erectile dysfunction and beyond

Abstract Tadalafil, Cialis, Eli Lilly & Co./ICOS, (6R,12aR)-6-(1,3-benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12ahexahydropyrazino[10,20:1,6] pyrido[3,4-b]indole-1,4-dione, was first discovered in 2003. It was reported to have high diastereospecificity for phosphodiesterase 5 (PDE5) inhibitions...

www.excelmale.com

Wow that is a lot of info, thanks...

I did not take any yesterday but will try again tonight... although I feel achy this morning... legs back... Hmm... side effects? Will try again to see if the achyness returns or worsens... I read that for some the sides go away with use eventually...

This is a very powerful drug... I had no idea...

 

[tropicaldaze1950]

Always glad to hear when something works for us older guys. Makes me sad, too. Even the tiniest dose(less than 2 mg) of tadalifil gives me gastro discomfort, mild headache and significant nasal congestion. I've tried the liquid version from BSP. Same sides. My wife, the few times she has been in the mood, thinks I should just get an erection the way I did, years ago. She has no interest in understanding male physiology.

 

[LakeGuy81]

2.5-5 mg is the dose used when taking daily.

Many are using 5 mg/day but others may experience the beneficial effects when using a dose on the lower end of 2.5 mg/day.

Defy has me taking 1/4 of a 25MG pill (6.25mg) daily, I wonder if this is too much? But I'm also currently off TRT, so maybe they boosted it up to help me out. I do l think it's helping, as I'm able to have decent sexual encounters and orgasms even with low T in the 200-300 range. Defy prescribed it as kind of a "hold me over" until I get back on TRT, if I do. Lastly, is everyone taking the ODT's (Oral Disintegrating Tablets) or a normal pill you swallow?

 

[Sergel]

Always glad to hear when something works for us older guys. Makes me sad, too. Even the tiniest dose(less than 2 mg) of tadalifil gives me gastro discomfort, mild headache and significant nasal congestion. I've tried the liquid version from BSP. Same sides. My wife, the few times she has been in the mood, thinks I should just get an erection the way I did, years ago. She has no interest in understanding male physiology.

So sorry it does not work for you... My girl is so sweet, never complained always played the hand she had... I have a great life companion... So imagine the giggles we have with this new renewed stiffy... I take it after lunch and no gastro issues... I take the original Lilly version if that makes a difference.

 

[Sergel]

Defy has me taking 1/4 of a 25MG pill (6.25mg) daily, I wonder if this is too much? But I'm also currently off TRT, so maybe they boosted it up to help me out. I do l think it's helping, as I'm able to have decent sexual encounters and orgasms even with low T in the 200-300 range. Defy prescribed it as kind of a "hold me over" until I get back on TRT, if I do. Lastly, is everyone taking the ODT's (Oral Disintegrating Tablets) or a normal pill you swallow?

My short research found that many guys will work well with small doses, like 2.5 or 5mg... so I guess you would still be considered in the small doses... I mean a full dose is like 10 or 20 or 25 in your case...

I could not imagine being off TRT ... hope you can go back on soon...

I take the original Lilly Cialis, so regular swallow pills. My doc gave me 5mg that I cut in two..

 

[Sergel]

Glad to confirm that just 2.5mg works wonders for me on demand... Darn... This is a very powerful drug... I am just amazed... Little context maybe. I am in good physical shape, good cardiovascular health, no health condition to speak of my only other medication is TRT ... So I guess that probably plays a role in why such a small dose works... It just gives me the little boost I need to perform better...
Anyhow, hope this thread helps someone...

I am so grateful for this forum...

 

[Willyt]

A belated thank you to @Sergel.
Over the last several years, I would sporadically use PDE-5 inhibitor at game time and got popped by the usual side effects every time (stuffy nose, wicked headaches, hangovers, backaches, etc.). I gave low dose daily Cialis/Tadalafil a shot at 2.5mg per day, but still had same side effects.

About 2 months ago, I decided to give daily Cialis one more shot after re-reading this thread. However, this time I tried microdosing at 0.62mg per day (1/4 of 2.5mg pill). To my surprise, I started reaping the benefits without the usual Cialis hangover. Eventually I got tired of trying to quarter the pills so I moved to 1.25mg (1/2 pill) every other day (EOD) with very similar results (despite the supposed 36 hour duration of Cilalis). I try to take each dose sublingually for better absorption although this is not always easy with such a small split pill.

This 1.25mg EOD dose is laughably low for many of you. The caveat is that I am sensitive to most medications. But the results have been promising so far (jinx). While microdosing does not provide the same intense experience as a normal dose, the effect has been consistently noticeable and without the nasty sides (as of yet).

The post-script is that I am starting to also appreciate the ancillary non-sexual benefits that many attribute to daily Cialis, some of which may be placebo effect. That topic goes beyond scope of this thread, but its something to explore (along with the potential downsides of long-term use)!

 

[TXLongHorn55]

A belated thank you to @Sergel.
Over the last several years, I would sporadically use PDE-5 inhibitor at game time and got popped by the usual side effects every time (stuffy nose, wicked headaches, hangovers, backaches, etc.). I gave low dose daily Cialis/Tadalafil a shot at 2.5mg per day, but still had same side effects.

About 2 months ago, I decided to give daily Cialis one more shot after re-reading this thread. However, this time I tried microdosing at 0.62mg per day (1/4 of 2.5mg pill). To my surprise, I started reaping the benefits without the usual Cialis hangover. Eventually I got tired of trying to quarter the pills so I moved to 1.25mg (1/2 pill) every other day (EOD) with very similar results (despite the supposed 36 hour duration of Cilalis).

This 1.25mg EOD dose is laughably low for many of you. I am admittedly sensitive to most medications. But the results have been promising so far (jinx). While microdosing does not provide the same intense experience as a normal dose, the effect has been consistently noticeable and without the nasty sides as of yet.

The post-script is that I am starting to also appreciate the ancillary non-sexual benefits that many attribute to daily Cialis. That topic goes beyond scope of this thread, but its something to explore (along with the potential downsides of long-term use)!

Can you comment on the manufacture of the 2.5 mg tadalafil you are usin?. Some pills are round and some are oval. The oval ones are impossible to cut in 1/4. Trying to locate a manufacturer that has 2.5 mg in the round shape. Thanks.

 

[Willyt]

Can you comment on the manufacture of the 2.5 mg tadalafil you are usin?. Some pills are round and some are oval. The oval ones are impossible to cut in 1/4. Trying to locate a manufacturer that has 2.5 mg in the round shape. Thanks.

The oval ones. You highlighted exactly why I moved from .62mg Daily to 1.25mg EOD - I couldn't quarter the oval pill with any precision. As I mentioned above, the results subjectively feel more or less the same.

One thing to note is that I originally had Empower 25mg pills which are very difficult to break down to a microdose with any degree of accuracy. I had to order the 2.5mg Tadalafil from my regular doctor. I cannot tell who the manufacturer is, but Walgreens fills the prescription if that helps.

 

[TXLongHorn55]

The oval ones. You highlighted exactly why I moved from .62mg Daily to 1.25mg EOD - I couldn't quarter the oval pill with any precision. As I mentioned above, the results subjectively feel more or less the same.

One thing to note is that I originally had Empower 25mg pills which are very difficult to break down to a microdose with any degree of accuracy. I had to order the 2.5mg Tadalafil from my regular doctor. I cannot tell who the manufacturer is, but Walgreens fills the prescription if that helps.

Thanks for the response. In the 5 mg option Walgreens has dispensed the round ones as well as the oval ones. Have been on the search for the round ones in the 2.5 mg option. It looks like Costco may have the round 2.5 mg option. Will follow up once confirmed.

 

[TXLongHorn55]

Thanks for the response. In the 5 mg option Walgreens has dispensed the round ones as well as the oval ones. Have been on the search for the round ones in the 2.5 mg option. It looks like Costco may have the round 2.5 mg option. Will follow up once confirmed.

Following up - can confirm that the 2.5 mg pills from Costco are round which make splitting easier. The pills are from NorthStar.

 

[TXLongHorn55]

The oval ones. You highlighted exactly why I moved from .62mg Daily to 1.25mg EOD - I couldn't quarter the oval pill with any precision. As I mentioned above, the results subjectively feel more or less the same.

One thing to note is that I originally had Empower 25mg pills which are very difficult to break down to a microdose with any degree of accuracy. I had to order the 2.5mg Tadalafil from my regular doctor. I cannot tell who the manufacturer is, but Walgreens fills the prescription if that

the 2.5 mg pills from Costco are round which make splitting easier. The pills are from NorthStar.

The oval ones. You highlighted exactly why I moved from .62mg Daily to 1.25mg EOD - I couldn't quarter the oval pill with any precision. As I mentioned above, the results subjectively feel more or less the same.

One thing to note is that I originally had Empower 25mg pills which are very difficult to break down to a microdose with any degree of accuracy. I had to order the 2.5mg Tadalafil from my regular doctor. I cannot tell who the manufacturer is, but Walgreens fills the prescription if that helps.

FYI - the 2.5 mg pills from Costco are round which make splitting easier. The pills are from NorthStar.

 

[Willyt]

FYI - the 2.5 mg pills from Costco are round which make splitting easier. The pills are from NorthStar.

What dose have you been taking daily? What are your observations so far?

I was doing well on microdose of 1.25mg EOD for number of weeks, but then started experiencing some acid reflux which I rarely get normally.