Do u know specifically what he has ur friend do to get off the SSRI and get his libido back? Mostly curious if pregnenolone/ DHEA played a role
Exactly. At the end of the day it’s all about trial and error and seeing what works and what doesn’t. Sometimes we have to experiment on ourselves, with labs, to figure these things out. A lot of the experimenting I’ve done throughout my time on HRT has been for me to learn and see what works for me obv, but also to figure out things that haven’t really been explored by many on HRT, and to hopefully help guide others better. I wish all this work had already been done prior to me starting HRT, but at the same time it is kind of cool working together with everyone to figure this stuff out. But again, would MUCH prefer to have all this stuff already figured out by other people prior to me starting this journey lol
SubQ can work for some, but IM will work for everyone. If ur having trouble dialing in, I would just switch to IM to at least have one less variable to worry about, in regards to why ur not feeling optimal yet
I think the regimen included a bunch of supplements in changing doses, I dont think there was preg and dhea, but some other stuff I dont remember, I can recall only melatonin.
I would sum this the same way, just to open a bracket - by IM I guess we both mean real deep old school IM(not meaning to use a harpoon), but also not this half inch IM that leaks into the fascia and maybe outside or will turn into a pure sub q depending your body fat level.
Hahah I won’t. My girl got off her SSRI just with testosterone alone. I’m sure optimizing his testosterone probably had the biggest effect, in regards to being able to get off his SSRI. Quality sleep I’m sure played a huge part thoI think the regimen included a bunch of supplements in changing doses, I dont think there was preg and dhea, but some other stuff I dont remember, I can recall only melatonin.
But my friend had very specific issues, when he stopped his SSRIs he got pain all over the muscles on the body and one night he got to go to the ER to get pain killers. So please dont take this as "Dave Lee stops SSRIs with melatonin"
Do u mind linking the syringes u get? I would love to use a 3/4” 27 gauge, but I didn’t know they made them. I’ve only been able to find 27 gauge in 1/2”. 27 gauge is my favorite tho. I’ve tried 28 and 29 guage, and 27 gauge is the perfect sweetspot for me
Yawns
To be honest I buy them from the pharmacy, they are very common here but now a bit harder to find because they use them for vaccination.
I live in the u.s. Oh ok, that makes sense. I was only looking at syringes with non-detachable needles. Does any of the oil get lost in the needle with attachable needle tips?
it does, but why should I care? I use the same type of syringes and needles for all my injections so the amount of oil that gets lost is always the same
This is a pretty poor example for the point being argued. On the one hand you have published, peer-reviewed studies measuring objective parameters and performed under controlled conditions. On the other hand you have a few random subjective reports from guys on the Internet, without even a plausible hypothesis to support the varying claims. Even if there are subjective differences they in no way undermine the studies, which are merely showing that absorption with SC is comparable to IM.
In what way did subq disagree with you? What issues did it cause?
The studies showing that is why the fail epicly in this specific case. For me and other guys there was a huge difference in blood levels on the same dose between sub q and IM. With me it was approximately 1/3 of the total t value.
@ivkonst2017 and others on IM, do you mind sharing your experience with IM vs. SC? Was there a difference in the subjective experience? If so, would you tie the problems with SC specifically to lower levels?
Or maybe the failure is yours. Did you take multiple blood samples to ensure an accurate computation of area under the curve? Did you studiously inspect your injection sites to ensure no leakage? Can you be completely certain the testosterone concentrations were the same? Did you simultaneously measure SHBG to ensure it didn't change, thus altering total testosterone?
Great point. Ur 100% correct. As long as ur using the same exact syringe and needle each time u get labs and adjust ur dose it doesn’t matter one bit
Ime, it’s more than just a few random guys. I’m part of this forum, a few other HRT forums, and about 6 HRT related fb groups. Over the 8 years that I’ve been doing research on HRT, I’ve definitely seen hundreds and hundreds of men that had to switch back to IM after trying subQ. Most of them backed up via bloodwork. There’s just something causing some people to have pretty drastic differences in labs when going to subQ from IM. Not sure exactly what it is. I never considered switching to subQ, so it’s not something I’ve personally delved into a great deal.
