low shbg means high free E2 ?

[locutus]

I thrive at 470-550 and have low SHBG. These Total T levels produce Free T in the 20-25 pg/mL ranges.

My E2 runs 50+ at these levels and I feel fine.

I am very similar to this, total T ~500, free T ~30, E2, ~50, low SHBG, good igf1
feel good.

 

[Charliebizz]

I am very similar to this, total T ~500, free T ~30, E2, ~50, low SHBG, good igf1
feel good.

What’s your protocol look like ?

 

[tonino]

Hello there i am new here .My TT is 1000-Estradiol 58-High FT and Low Shbg.
Should i lower T dose or should take some arimidex?
.25ml T x 2 weekly. Thanks

 

[Systemlord]

Hello there i am new here .My TT is 1000-Estradiol 58-High FT and Low Shbg.
Should i lower T dose or should take some arimidex?
.25ml T x 2 weekly. Thanks

Just lower your T dosage.

 

[tonino]

Thanks, will try that.

 

[TestQuest22]

As a guy with low SHBG, I'm tracking you guys to see what I should do next. All I know is I think I might be exhibiting issues of too much DHT and/or estrogen sensitivity (slight balding, hair thinning, lots of back acne, and some water retention 8 months into this), so I wonder if my "daily injection because of low SHBG" protocol makes that better or worse. I'm injecting 16mg a day right now, and the acne seems to have no intentions of slowing down.

 

[JA Battle]

As a guy with low SHBG, I'm tracking you guys to see what I should do next. All I know is I think I might be exhibiting issues of too much DHT and/or estrogen sensitivity (slight balding, hair thinning, lots of back acne, and some water retention 8 months into this), so I wonder if my "daily injection because of low SHBG" protocol makes that better or worse. I'm injecting 16mg a day right now, and the acne seems to have no intentions of slowing down.

I would try to work that down to 8mg. Also systemlord has had great success with jatenzo

 

[tonino]

Just lower your T dosage.

I forgot to ask how much should i lower it?

 

[Systemlord]

I forgot to ask how much should i lower it?

Normally if you're not too far off the mark, I would say subtract 10-20mg, but in your case reduce 30mg off your total weekly dosage.

The one thing I noticed about TRT dosing, is it's not linear and you don't subtract 50% of your dosage and end up with half the levels. There is a threshold where levels start climbing exponentially.

 

[Anonymon]

Also usually better to lower things gradually and not all at once if it’s a big change. I recently reduced my dose by 30% and it got real rough real quick. I’ve been at that same dose before without issue, the main thing being the big change.

 

[Cataceous]

...
The one thing I noticed about TRT dosing, is it's not linear and you don't subtract 50% of your dosage and end up with half the levels. There is a threshold where levels start climbing exponentially.

There must be some confounding factors in your observations. Free testosterone is generally going to be linear with dose. More details here. With unchanging SHBG total testosterone should also appear to be fairly linear in dose. My own data, for example:

 

[tonino]

Normally if you're not too far off the mark, I would say subtract 10-20mg, but in your case reduce 30mg off your total weekly dosage.

The one thing I noticed about TRT dosing, is it's not linear and you don't subtract 50% of your dosage and end up with half the levels. There is a threshold where levels start climbing exponentially.

Thanks again

 

[equel]

Any new thoughts on this?

 

[Omi7276]

Basically by increasing insulin sensitivity. Keto and carnivore diets are both notorious for raising SHBG

DNP is king of improving insulin sensitivity, yet it does so little to bring up SHBG

 

[BillyJ03z]

How does one increase shbg?

Taking Thyroid meds raises SHBG and improves lipids.

 

[GreenMachineX]

Taking Thyroid meds raises SHBG and improves lipids.

Oh ok, I'm already on thyroid meds.

 

[t_spacemonkey]

my shbg is 11 or so. my total T usually around ~500ng/dl. e2 60. free T 20-40ng depends on the day of measurement.
overall I feel pretty good on those levels. my optimal dose is somewhere between 140-200mg. if i go lower I feel like I am on not T at all

 

[BillyJ03z]

Maybe larger daily doses might be better for low SHBG. I'm on 20mg Cyp ED/SQ, but maybe I should bump higher to 25 or 30 for trial run... but then my E2 and DHT would sky rocket probably...