Levels

[scguy2020]

just had a question i was getting 240 a week and i was dropped to 200 a week due to severe Acne. then i got really sick and depressed and lost my sex drive i felt like i was going crazy. the kept the lover does for two weeks now i'm back on the 240 but still dont feel the best. was wondering if my body was going into shock due to the drop in dosage. i just was wondering if that is why i stated feeling bad. i went to a urgent care doctor and he said that was most likely my issue. any insight would be great.

 

[MarkM]

Welcome to the forum scguy.........

Your body is more than likely "going into shock" over the large doses of testosterone it is getting, 200 mg a week or 240 mg a week. We don't have any labs to look at but 200 mg is a high does for TRT and 240 mg is an extremely high TRT dose.

Those doses are probably spiking your E2 to levels that most people can't handle. The acne is likely due to excessively high DHT levels.

Are you seeing a doctor or self medicating? How long have you been on the 200 mg or 240 mg dosages? Are you taking one injection a week or multiple injections per week? Any idea what your testosterone levels are (Total Testosterone and Free Testosterone), Estradiol Sensitive, and SHBG? Any idea what your hemoglobin and hematocrit levels look like on this protocol? Can you post current lab work?

 

[scguy2020]

i am seeing a doctor. i was on the 240 for about 5 mo i was dropped to the 200 for two weeks then i was brought back to 240 last week. i take injections once a week.they were at 700 before i was dropped.i will have to get that from home currently at work.

 

[Vince Carter]

YOu have a very poor Dr. that's factual based on the (over) dosing and this up and down he's putting you through.

Acne has much more to do with E than DHT ever will but you need to have bloods pulled on both but it's across the board that acne is E related.

 

[Systemlord]

Everytime you increase or decrease the dosage you upset your testosterone blood levels, everytime you change dosages it take 6 weeks for your testosterone blood levels to reach a stable state. So by changing your dosage 2 weeks after decreasing makes no sense because you had 4 more weeks before you reach a stable state.

If you keep messing around with your dosages you'll NEVER reach a stable state. Your doctor doesn't even understand how this TRT game is played. Once weekly injections isn't idea unless you have very high SHBG, large infrequent injection produces large testosterone peaks followed be lows at the end of the week, this cause a hormonal roller coaster that never ends and gets worse as time goes on until you feel no relief after each injection.

Your SHBG will dictate injection frequency, the majority of doctors aren't properly trained on how to replace a man's hormones. I was force to seek private care because none of my endocrinologists knew what they were doing.

200mg is at the upper end of the limit for weekly doses, for most men it would simply be too much testosterone and you should expect to see ache and high estrogen symptoms at these dosages.

 

[Systemlord]

YOu have a very poor Dr. that's factual based on the (over) dosing and this up and down he's putting you through.

Acne has much more to do with E than DHT ever will but you need to have bloods pulled on both but it's across the board that acne is E related.

I thought DHT was responsible for acne, as I understand it DHT is related to skin therefore acne.

 

[Vince Carter]

when my E was astronomical I was all broken out, E much lower, not broken out. And that's using cream to the nuts to RAISE my DHT. DHT is incorrectly by the uninformed to be demonized when it's ESTROGEN. Same applies to Prostate, too...ESTROGEN.

added: basic verbatim from convo with Dr Saya

 

[MarkM]

................Acne has much more to do with E than DHT ever will but you need to have bloods pulled on both but it's across the board that acne is E related.

I agree that high E2 can create acne issues for men but we shouldn't discount the impact of DHT on acne. Since men naturally have more testosterone related hormones in their bodies, it is more likely that more of those analogs, such as DHT, may be found in the free form leading to an increased risk of acne. DHT can stimulate over-activity of the sebaceous glands, which causes your skin to produce more sebum. Therefore, one could conclude that increased levels of DHT result in greater acne formation.

So I do agree that a high estradiol level can create acne but I believe the preponderance of acne problems arise from excessive DHT. Everyone's body chemistry is different and everyone reacts differently to hormonal changes.

 

[MarkM]

when my E was astronomical I was all broken out, E much lower, not broken out. And that's using cream to the nuts to RAISE my DHT. DHT is incorrectly by the uninformed to be demonized when it's ESTROGEN. Same applies to Prostate, too...ESTROGEN.

added: basic verbatim from convo with Dr Saya

I don't believe Systemlord or I are demonizing DHT at all. Just stating our belief. I am actually a big fan of DHT and have levels over the top of the range. Like I said, all of us have differing body chemistry and hormones impact us all differently. Speaking for myself, I may not have your level of knowledge but I don't consider myself uninformed.

 

[scguy2020]

thank you guys i'm so frustrated right now with all this such a head ach

 

[MarkM]

thank you guys i'm so frustrated right now with all this such a head ach

You might want to consider a new doctor. Your current doctor set you up all wrong which is why you are so frustrated. He hasn't given you very good care at all. Defy Medical and Prime Body are two groups that have members that participate on this forum. They offer a tele-med service which is really the future of a lot of medical care. They are very knowledgeable and are experts at testosterone therapy. Here are links to their websites:

https://www.defymedical.com/
http://www.primebody.com/

 

[Systemlord]

Testosterone increases, estrogen will follow and DHT will likely increase as well. Testosterone is converted into estrogen and DHT, so if estrogen is elevated then so to is DHT.

I believe estrogen it gets a bad rap when there are other factors at play.