I’m in hell

[diegoamartin7]

Low SHBG issues dialing in,

So I started TRT again after taking a year off from it, pre try my leveled where 402 TT, 9FT, e2 24
had issues with libido , ED and morning wood nonexistant, plus some bad crash when i took proviron a couple times, felt horrendous like low T and low E2,
Tried clomid, gave me permanent eye floaters but i felt good on it, despite getting my test to just 710 and free test of 13, but ed and libido where not perfect

now I’m trying to do a simpler approach, enanthate only, sub q every day, 120mg a week
But there is a very poor reponse
My shbg is low at 13.5
e2 mildly elevated at 34
prolactin at 7
totally test is 560
free test is 13,2

I’m having very bad ED issues, that are causing extreme depression, i’m feeling really bad guys, so bad i have considered suicide at times, because it’s so frustrating no being able to see the benefits of try and only making things worse.

My glycosilated hemoglobin is 4.8
tsh is at 2 (take 50mcg t4

Why proviron crashes me? why is my shbg is low and yet my free testosterone is also low? i feel like a ruined my life, any support would be appreciated

 

[FunkOdyssey]

The ED problem should be addressed directly with ED meds. ED is easily fixed with those medications and should not be causing you any major distress. Start with PDE5 inhibitors - if they don't work well enough, move on to intrapenile injections which certainly will.

What was your baseline TSH, free t3 and free t4 prior to starting thyroid meds? The 50 mcg T4 is a sub-replacement dose, which in most cases will not result in any net increase of thyroid hormone, but instead will reduce your free t3 level relative to baseline. This means there's a good chance you are functionally in a worse hypothyroid state than your unmedicated baseline. Most people who think they need thyroid meds don't.

You should not be concerned with your response to proviron. I, and many other people, do not feel good on proviron. It's not a natural hormone and it has strong anti-estrogenic effects, at least subjectively speaking. There's no use stressing about it, or trying to troubleshoot that further. Just file your experience away as a data point, and move on.

Your poor response to subcutaneous injections is not uncommon. I would suggest trying at least shallow IM with 1/2" needles instead, using delts and/or ventroglutes.

Also, you don't want to change too many variables at once, but daily injections of long esters are often not optimal for libido and sexual function. If your dose response and free T level improves with IM, but the sexual symptoms are still present, the next thing to try would be lower injection frequency.

The depression you are dealing with sounds serious, and needs to be addressed independently of the TRT. Depression alone can cause all of your sexual symptoms BTW. You should be doing everything within your power here to address it, including daily exercise, eating only clean whole foods (keto diet in particular is powerful for mental health), disciplined sleep schedule to maintain a healthy circadian rhythm, disciplined mental hygiene (rejection of runaway rumination, critical examination of cognitive distortions), and ample social interaction. Seek professional help if you are struggling to implement these in your life, if you've succeeded and are still suffering, and especially if you continue to experience suicidal thoughts.

Best of luck to you.