Help me make up my mind about a change in protocol

Gianluca

Well-Known Member
Hi guys,

After trying subQ injection for my 3rd time with no success, I think I'm left to go back to IM injections. I just don't absorb subQ as well as IM.

I'm debating if I should go back again to either EOD or ED as injection frequency.

I would choose ED as a peace of mind about having more stable levels and less mood/emotional swings, (my SHBG is at 10). However, I think about scar tissues build up in the muscles. I also noticed 2-3 times already, that every time I add the ventrogluteal injection site, my T level drop, so I would be left injecting into quads and delts, basically rotating 4 injection sites.
I noticed when doing ED IM I would see often a lump developing on my delts, I use 29G 1/2in insulin syringe.

I thought about scrotal cream, but I'm not convinced about the excessive conversion into DHT, otherwise that would be a winner.

What do you guys think? do you perhaps have some better tips on how to rotate IM injection sites? @FunkOdyssey @Cataceous
 

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Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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