Help me dial in my protocol Nebido

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Chrander

Member
I most certainly will.

Btw. my T3 and T4 have always been very low. I do now, more than ever, want to take a closer look on those levels and see if they have contributed to me not feeling "optimal". Any thoughts?
 
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Cataceous

Super Moderator
I had lowish free T3 and free T4 along with upper-range reverse T3. It seems likely these were causing feeling of fatigue, which have resolved with low daily doses (5-10 mcg) of liothyronine.
 

Chrander

Member
Hi.

I have now skipped 2 shots of Nebido. Felt ok, but little libido.

Startet 40 iu today and will continue this dosage and test again in mid July.

Started taking 1 Brazil nut ED in the morning to check if it can help my t4/t3.

I want to dig deeper into my possible hypothyroidism. Low t3 and t4 and high TSH.

If ANYONE can help me with this, its very much appreciated.

Have a great day.
 

DragonBits

Well-Known Member
Hi.

I have now skipped 2 shots of Nebido. Felt ok, but little libido.

Startet 40 iu today and will continue this dosage and test again in mid July.

Started taking 1 Brazil nut ED in the morning to check if it can help my t4/t3.

I want to dig deeper into my possible hypothyroidism. Low t3 and t4 and high TSH.

If ANYONE can help me with this, its very much appreciated.

Have a great day.

I posted what you should do about your T3/T4, mainly test for thyroid antibodies, it's possible you have hashimoto. And less important test for Rt3 if possible.

The selenium / iodine isn't likely a cause, but it's certainly possible and easy to just eat a brazil nut or supplement to see how it works.

hypothyroidism or low T3 can negatively affect libido and energy levels.

I am not a fan of "optimising " T3 to the upper part of the range, but you are below normal, which is more significant.

First, I would make sure you get enough selenium and iodine in your diet. Be very careful about supplementing iodine, high levels suppress thyroid function. I try and eat 1 brazil nut a day for selenium, since I use iodized salt and sometimes eat seaweed, I expect I get enough iodine from that. Once I did supplement too much iodine and my TSH started to climb and T3 fall.

If you can test Reverse T3 and thyroid antibodies I suggest you discuss that with your doctor and see if they can test for them, especially thyroid antibodies. I don't recall if you said what country you live in, reverse T3 may not easily be available and it's controversial if it's all that important. Some docs say yes, many don't think it's important. Though my reverse T3 is 14.6 which most people think is good, so that is another reason I don't think much about it.

I am a little surprized you doctor hasn't mentioned this, and why haven't you done any thyroid antibody testing?
 

Chrander

Member
Hi.

Little unsure who this was meant to, but I can say for me that 0,5ml is too much. I decreased my dosage to 0.4ml. Will test again in 3 months.
 

Chrander

Member
I posted what you should do about your T3/T4, mainly test for thyroid antibodies, it's possible you have hashimoto. And less important test for Rt3 if possible.

The selenium / iodine isn't likely a cause, but it's certainly possible and easy to just eat a brazil nut or supplement to see how it works.



I am a little surprized you doctor hasn't mentioned this, and why haven't you done any thyroid antibody testing?

Yes, me too. In my country the expertise in this field is very low. Sadly.. I have to do some research regarding this test. I really want to test for it.

I do test for free t3 and t4 every time. My list of test should look like this?

Free T3
Free T4
rT3
Thyroid peroxidase antibodies (TPO)
Thyroglobulin antibodies (Tg)
Thyroid-stimulating hormone (TSH) receptor (I do test for this)

Anyone else? I hope I can get them tested.

Have a great day and thanks a lot for helping out. Much appreciated.
 

Chrander

Member
Hi.

Got some of my newest labs in. Was supposed to only take the above mentioned (t3,t4, TPO ++), but I also checked the hormones I usually test for as well.

Please see the picture attached.

The test was taken on a Friday, after I skipped two Sundays of injecting, and injecting once 40iu the previous Sunday.

You can see my testosterone has fallen a lot and into a more healthy number. I imagine it will increase some the next following weeks.

TPO was in normal range. Anyone that has anything to comment regarding my thyroids? I do some values is a little late and not arrived yet.

Libido is bad and I now feel a little "down", but that was to be expected after dropping the dose a bit (from 54iu to 40iu). I do hope to feel better..
 

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arynne

New Member
Hi.

A little over 30y old and prescribed Nebido as trt from my doc. No guidance at all, so I want to get help from you nice guys:)
  • 87-91kg
  • 8% +- fat (3,2 mm: 12 point caliper test)
  • 2800-3200 calories. Slowly reverse dieting.
  • Moderate to high activity. Training 5 days a week. 10-15k steps a day.
  • Strength training + mtb
  • Engineer
  • Melatonin 3mg ED
  • L-tyrosine 750mg in the morning
  • 5000iu Vit D3 (levels always normal)

TRT:

I started Nebido 17w ago. A little unconventional protocol, but here we go; 4ml split into two injections sites: w0, w3 and w6, followed by an injection at w11.
  • Took some Tamoxifen along the way (about two weeks in total) du to development of tissue behind the nipples. All gone.
Now I am testing my levels every week (Thursdays) (done so from of week 15).
  • Started 20mg tamoxifen Friday in week 15 due to new gyno development and S-estradiol-17beta: 0.20 (ref: 0-0,17) tested in w15, so a little high estrogen.

w15 (no tamoxifen, started the day after when labs came back with 0.2 estrogen):
F-test: 9.1 2,3- 9,9
S-test: >50 8- 35 nmol/l
Prolactin 137 <700
TSH: 3.1 0,2-4
Free t3: 3,8 3,5- 6,5
Free t4: 11,7 11-23
SHBG: 55 8-60
S-estradiol-17beta: 0.2* 0-0,17


w16:


F-test: 9.4 2,3- 9,9
S-test: >50 8- 35 nmol/l
Prolactin 77 <700
TSH: 2,5 0,2-4
Free t3: 3,5 3,5- 6,5
Free t4: 11,9 11-23
SHBG: 53 8-60
S-estradiol-17beta: 0.13 0-0,17

Got down to 10mg tamoxifen Friday w16.

Lates test (w17, yesterday):

Test was done in the morning not fasted (shake ++)

F-test: 7* 2,3- 9,9
S-test: 47 8- 35 nmol/l
Prolactin 152 <700
TSH: 3,5 0,2-4
Free t3: 3,7 . 3,5- 6,5
Free t4: 13,7 . 11-23
SHBG: 67* . 8-60
S-estradiol-17beta: 0.12
  • 5mg tamoxifen starting today (Friday w17) for one week. Tapering down from the 20mg.
So my total testosterone is now below 50 and "detectable" for the labs. Free test is a little lover and SHBG is higher. Could this be due to the usage of tamoxifen?
  • Low libido. My penis is "dead". I can get it hard, but I am not horny..
  • Many huge ups and downs (mood swings). Might even think it is a depression I am feeling.
    • Maby due to estrogen and the amount of testosterone in my body. Nebido is working slow, so I am just starting..
  • Not feeling great.
My Q:
  • When to add my next Nebido injection? This week or next? More labs? In need for my total test to lover more?
    • I want to be at upper level testosterone
  • What to do regarding high SHBG (could it only be tamoxifen?)
  • Libido..
  • Do not want to use an AI if I do not need one
All other input is very well tolerated..

Thank you:)
This is para-obsessional stuff. Either you feel better on TRT 1000 Q 10 weeks or you don't. End of. Blood levels are neither here nor there. But I'm probably wasting my breath on the desert ait!
 

Chrander

Member
Hi.

Today I received this Friday blood samle results.

Short recap;

To high testosterone back in April (see attachment). So I skipped two dosings (two Sundays) and went down to 40 iu every Sunday. Se sample in May (just wanted to see how low it became before the new adjusted dosage, not stable values jet off corse).

Then I waited and took a sample 9. July. My values was then starting to stabilised I think. But I waited even longer and took a sample yesterday (Friday morning) and as you see It had risen a bit.

I usually take sample on Thursdays or Fridays every time.

So as you all see my levels is still quite high after only taking 40 iu Nebido every Sunday.

Notes (40 iu);
Energy is great.
Muscle is coming great.
Hematocrit is a little high.

Libido; Little to NO at all. Ejaculation volume is low (if I wait some days in between, the volume creeps up).

My ONLY concern now is LIBIDO. Very frustrating:( And it keeps me "waiting" for life.. Have tried Cialis, but its not a symptom fixer and my dick can easily lose its hardness, especially if I have sex in the dark and not in the correct sexual mood. I am a visual guy.. hehe. My dick feels"numb" and little sensitive. I have to really look at something "perfect" when it comes to porn to get in the right mood. I do think of sex often and I like girls A LOT, but still..

Have I waited long enough from last adjustment to say its ok to adjust once more? Nebido is a horrible product when it comes to getting dialed in:( But its my only possibility.

Is the lack of "peaks" a reason for little libido?

I am looking forward hearing from you all. What to do next. Tomorrow is Sunday and injection time.. Should I skip one dosage, adjust lover? ++ Please give your two cents.

Everything is great,
 

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Last edited:

Nik

Member
Hi.

Today I received this Friday blood samle results.

Short recap;

To high testosterone back in April (see attachment). So I skipped two dosings (two Sundays) and went down to 40 iu every Sunday. Se sample in May (just wanted to see how low it became before the new adjusted dosage, not stable values jet off corse).

Then I waited and took a sample 9. July. My values was then starting to stabilised I think. But I waited even longer and took a sample yesterday (Friday morning) and as you see It had risen a bit.

I usually take sample on Thursdays or Fridays every time.

So as you all see my levels is still quite high after only taking 40 iu Nebido every Sunday.

Notes (40 iu);
Energy is great.
Muscle is coming great.
Hematocrit is a little high.

Libido; Little to NO at all. Ejaculation volume is low (if I wait some days in between, the volume creeps up).

My ONLY concern now is LIBIDO. Very frustrating:( And it keeps me "waiting" for life.. Have tried Cialis, but its not a symptom fixer and my dick can easily lose its hardness, especially if I have sex in the dark and not in the correct sexual mood. I am a visual guy.. hehe. My dick feels"numb" and little sensitive. I have to really look at something "perfect" when it comes to porn to get in the right mood. I do think of sex often and I like girls A LOT, but still..

Have I waited long enough from last adjustment to say its ok to adjust once more? Nebido is a horrible product when it comes to getting dialed in:( But its my only possibility.

Is the lack of "peaks" a reason for little libido?

I am looking forward hearing from you all. What to do next. Tomorrow is Sunday and injection time.. Should I skip one dosage, adjust lover? ++ Please give your two cents.

Everything is great,
Como se arregla para divir su dosis , nebido tengo entendido viene en ampollas de 4ml al menos en mi pais .
 
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