Gene's Nitric Oxide Stack

Many have used this stack for massive hard pumps in the gym, significant vascularity and excellent erectile function not discounting the health benefits. If you're looking for any of these benefits and more...give it a try!

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)

Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)

More Than a Muscle Pump: The Surprising Science of the Nitric Oxide Stack​

In the biohacking world, we often chase complex peptides or experimental compounds, but we frequently overlook the most fundamental currency of life: blood flow. In the quest for longevity, systemic vascular efficiency is the baseline upon which all other health markers are built. As we age, our ability to maintain vasodilatory capacity diminishes, impacting everything from cognitive sharpness to metabolic health. "Gene’s Nitric Oxide Stack," a protocol born and refined within the ExcelMale community, has emerged as a definitive solution for men seeking to optimize this system. This isn't just a gym supplement routine; it is a sophisticated approach to anti-aging that leverages amino acids and targeted pharmaceutical interventions to restore the body’s most vital delivery mechanism.

Beyond the Mirror: The Science of the Sustained Pump​

For the average gym-goer, the "pump" is a transient aesthetic goal—a fleeting moment of muscle fullness. However, for a longevity specialist, a "harder pump" and increased vascularity are indicators of high-functioning endothelial health. The Nitric Oxide Stack is engineered to produce a state of vasodilation that doesn't simply vanish when you rack the weights.

By optimizing the nitric oxide signaling pathway, this protocol facilitates a sustained pump that carries through your daily life. This is a critical distinction: the visual vascularity is a proxy for your body’s ability to keep its "pipes" open. When you maintain that fullness hours after a workout, you are essentially providing proof of concept that your circulatory system is operating at peak efficiency, ensuring constant nutrient delivery to peripheral tissues.

The Foundation of Performance: Hard Science for Sexual Vitality​

One of the most immediate benefits of systemic vasodilation is the restoration of sexual function. From a clinical perspective, erection quality is often the "canary in the coal mine" for cardiovascular health. Because the Nitric Oxide Stack focuses on the root physiological requirements of performance—blood flow and retention—it provides a robust alternative to temporary fixes.

A Serious Solution for Erection Quality and Duration

This stack addresses both the quality and the duration of erections with clinical precision. For men navigating the aging process, this is not a matter of vanity, but of maintaining vital physiological function. By ensuring the vascular system can respond effectively to neurological signals, the protocol allows for a level of performance that many mistakenly believe is lost to time.

The Ultimate Nootropic: Future-Proofing the Neocortex​

Perhaps the most compelling argument for nitric oxide optimization is the "bodybuilder to brain health" pipeline. While most men start this stack for its physical benefits, they are unknowingly deploying a powerful shield against age-related cognitive decline. As we age, the micro-vasculature within the brain tends to narrow and tighten, a process that starves the brain of oxygen and is a primary driver of age-related dementia.

The stack acts as a nootropic by ensuring that the brain's smallest vessels remain dilated and resilient. This ensures that the neocortex and other critical regions receive a constant supply of the nutrients required for cognitive longevity. As the source material highlights:

"by increasing nitric oxide and getting that vascular dilation we're getting oxygen blood and nutrients in the areas of the brain that can provide us with a great anti-aging benefit in terms of neurological health."

The irony is profound: a protocol often associated with the bicep curl may actually be one of your most effective tools for protecting your mind.

Systemic Management: Blood Pressure and Prostate Function​

The benefits of the stack extend into the deeper mechanics of men’s health, specifically regarding the relaxation of smooth muscle tissue. This is particularly relevant for Benign Prostate Hyperplasia (BPH) and blood pressure management. Nitric oxide serves as a signal for these tissues to relax, directly easing the "inability to ease the problems" that typically characterize age-related prostate issues.

The secondary physiological advantages of this systemic relaxation include:

• Vascular Tension Reduction: Significant support for maintaining healthy blood pressure levels by reducing resistance within the arterial walls.
• Prostate Relief: Improvement in quality of life by relaxing the prostatic smooth muscle, easing the mechanical symptoms of BPH.
• Reduced Cardiac Load: By improving systemic flow, the heart is not required to pump against the same level of resistance, preserving cardiovascular longevity.

The Future of Your Vascular Health​

"Gene’s Nitric Oxide Stack" is far from a theoretical exercise; it is a "living protocol" backed by years of community peer-review within the ExcelMale community. The "enormously long" and widely viewed thread on ExcelMale.com serves as a testament to the real-world efficacy of this stack, offering a repository of shared experiences and optimization strategies.

This multi-front approach to anti-aging represents the best of biohacking: using fundamental biological pathways to solve complex aging problems. By focusing on the delivery system itself, we can protect our brains, our hearts, and our vitality simultaneously.

If blood flow is the delivery system for every nutrient your body needs, what happens to your longevity when you finally optimize that system?


More on Nitric Oxide in Men:

Nitric Oxide Pages

 

Oh, by the way, on the sleep problems - you might want to inventory everything that you ingest after, say, 5pm, as some of them disturb sleep:

* Definitely caffeine
* CoQ10
* ALCAR
* large doses of sugar

are just the ones I can think of at the moment.

As far as melatonin, it works well, but I only take it if I lie awake for more than 10-15 minutes (then I take one).

 

Great info in this thread. I'm 55 and in great health but 6 months post prostrate removal (nerve sparing)PSA is still 0.0 and can get non drug assisted erections with massive stimulation in 10 minutes but not what I want to use with the wife. (Masturbation in front of the leading lady is not romantic.)I can barely tolerate the side effects of cialis (reflux) but Viagra is a bit better. The question I have is I have now been prescribed Trimix and have fantastic results( saying it was like a hard piece of wood was an understatement) but I like the natural way for erections because of the romantic spontaneity it allows. Would you think this stack is something I should try or go with the Trimix for a while and then start using the stack as my penis rehabilitation is more advanced? Also, where is the best place to get most of these supplements in the stack?

 

That sounds way too medical to be answered by anyone other than a doctor.

The supplements in the stack are either by prescription, or else available at any "vitamin" source - online includes Amazon, vitacost, vitaminshoppe, iHerb, netrition.

 

Great info in this thread. I'm 55 and in great health but 6 months post prostrate removal (nerve sparing)PSA is still 0.0 and can get non drug assisted erections with massive stimulation in 10 minutes but not what I want to use with the wife. (Masturbation in front of the leading lady is not romantic.)I can barely tolerate the side effects of cialis (reflux) but Viagra is a bit better. The question I have is I have now been prescribed Trimix and have fantastic results( saying it was like a hard piece of wood was an understatement) but I like the natural way for erections because of the romantic spontaneity it allows. Would you think this stack is something I should try or go with the Trimix for a while and then start using the stack as my penis rehabilitation is more advanced? Also, where is the best place to get most of these supplements in the stack?

Nelson had posted this: "· NEVER take Tri-Mix or any ICP injection within same 24hr period as Viagra/Cialis/Levitra or other ED meds."
because of the danger of priapism, in this thread: Trimix Injections for Hard Erections- Part 2

 

No caffeine (tea, soda, nothing) after 3, but i drink tons of coffee all morning and day until then.
No sugar, desserts or things like that.
No other supps except what I listed.

I do drink a lot. and smoke. Had another rough night, waking every two hours. But... felt good waking at about 6.30, no alarm. Feels like the theanine is really that good in helping process out alcohol and keeping me relaxed even though i wake.

So about that liquid cia... part of my waking last night had to do with getting boners all night. Today is a new day. I haven't felt so good, haven't had such a positive outlook, haven't ever felt so confident. The stuff should be OTC. And crap like artificial cooking oils should be banned as poisons.

Day 2: Win!

 

Gene

I have purchased

L-Arginine
L-Citrulline
Pycnogenol

In powder form so in order to get the quantities you outline should I simply weigh it out in grams and can I then mix the powder into any liquid from water to juice to a smoothie to milk or a protein powder drink?

I dont want to cancel the effects by mixing it with the wrong liquid or ingredient.

 

I can give you my answer. I mix my powered L-Ag and L-Cit with POM juice about 4 oz and cold water. It works just fine and should be no downside to this.
I am sure others will comment too.

By the way the company DEFY which is a HRT company and more knows about Gene's Stacker. I am a patient of DEFY and my physician mentioned(reading my background info) that I was taking Gene's Stacker and I asked if he saw a problem with it and he said no the NO is a great.

 

I can give you my answer. I mix my powered L-Ag and L-Cit with POM juice about 4 oz and cold water. It works just fine and should be no downside to this.
I am sure others will comment too.

By the way the company DEFY which is a HRT company and more knows about Gene's Stacker. I am a patient of DEFY and my physician mentioned(reading my background info) that I was taking Gene's Stacker and I asked if he saw a problem with it and he said no the NO is a great.

Do you weigh or measure the ingredients?

 

Great info in this thread. I'm 55 and in great health but 6 months post prostrate removal (nerve sparing)PSA is still 0.0 and can get non drug assisted erections with massive stimulation in 10 minutes but not what I want to use with the wife. (Masturbation in front of the leading lady is not romantic.)I can barely tolerate the side effects of cialis (reflux) but Viagra is a bit better. The question I have is I have now been prescribed Trimix and have fantastic results( saying it was like a hard piece of wood was an understatement) but I like the natural way for erections because of the romantic spontaneity it allows. Would you think this stack is something I should try or go with the Trimix for a while and then start using the stack as my penis rehabilitation is more advanced? Also, where is the best place to get most of these supplements in the stack?

Ed - I use the stack along with Trimix and have no problems whatsoever...in fact, I think it enhances it and makes the post semi erection last almost into the next day...and it's very impressive to say the least.

Many many health benefits for the aging male in the stack so give it a try.

I use Vitamin Shoppe for most of my supplements including workout supplements so give them a try.

Of course Cialis needs a prescription if you intend to include it in your stack.

 

Gene

I have purchased

L-Arginine
L-Citrulline
Pycnogenol

In powder form so in order to get the quantities you outline should I simply weigh it out in grams and can I then mix the powder into any liquid from water to juice to a smoothie to milk or a protein powder drink?

I dont want to cancel the effects by mixing it with the wrong liquid or ingredient.

That sounds like a good plan.

Those three are very good for increasing vascularity just make sure to take this three times a day for optimal results.

 

That sounds like a good plan.

Those three are very good for increasing vascularity just make sure to take this three times a day for optimal results.

Well you really know you are hitting rock bottom when you start answering your own questions in forums but here I go,
: )

OK my objective was to hit the numbers on Genes supplements three times a day without swallowing a million pills or breaking the bank and being able to break the portions up quickly and easily.

The first thing I did was to by the supplements in powder form from Bulk Supplements

http://www.bulksupplements.com/

At first I was going to weigh the ingredients but talk about time consuming.

So I bought the citrulline for instance and the package actually displays dry measurement equivalents

[TABLE="class: us-spoons, width: 309"]
[TR]
[TH="class: a-center, colspan: 2, align: center"]US Standard Measuring Spoons[/TH]
[/TR]
[TR]
[TH="align: left"]Spoon Size(level)[/TH]
[TH="class: a-right, align: right"]milligrams[/TH]
[/TR]
[TR]
[TD="align: left"]1/4 teaspoon[/TD]
[TD="class: a-right, align: right"]699[/TD]
[/TR]
[TR]
[TD="align: left"]1/2 teaspoon[/TD]
[TD="class: a-right, align: right"]1400[/TD]
[/TR]
[TR]
[TD="align: left"]1 teaspoon[/TD]
[TD="class: a-right, align: right"]2800
[/TD]
[/TR]
[/TABLE]



so for 1500 MG you simply measure a bit more than 1/2 a teaspoon

The measurements are different for each ingredient so you simply look them up on the bulk supplements web site and portion accordingly

The tough one was the pine bark or 50 mg of Pycnogenol.
You can buy this in powder form but the measurement of 50 MG is 1/64 of a teaspoon but believe it or not there is such a thing and the technical term is a "drop" and for all of you wondering 1/32 of a teaspoon is a "smidgen"

The arginine measures out to a bit more than 3000 MG per teaspoon. So i simply measure all of the ingredients and blend them with milk use liquid cia and you could have a stack milkshake at maybe a price closer to a grande rather than a venti each day.

Hope this helps

 

I been exited to start Gene´s stack but only to 50%, L-Citrulline free form, L-Arginine, Beet root juice, DHEA, Q10 + vitamins etc.. with a daily dose of only 2,5mg Cialis. But to my sorrow I have to exclude Cialis now and only after a week due to pain in my lower back. Even such a small dosage has this effect on me. Could it be possible that my body get used to it after sometime or is it just forget about it? Anything that can substitute the Cialis?

 

I been exited to start Gene´s stack but only to 50%, L-Citrulline free form, L-Arginine, Beet root juice, DHEA, Q10 + vitamins etc.. with a daily dose of only 2,5mg Cialis. But to my sorrow I have to exclude Cialis now and only after a week due to pain in my lower back. Even such a small dosage has this effect on me. Could it be possible that my body get used to it after sometime or is it just forget about it? Anything that can substitute the Cialis?

After a week and a half muscle and back pain disappeared for me. Can you try and ride it out?

 

I will try, just some pain killers will do I´ll gues. By the way I have perfect BP now!

 

All the best.

 

After a week and a half muscle and back pain disappeared for me. Can you try and ride it out?

I had the same problem with back pain as well but rode it out and in a week or two it was gone as my body acclimated to the daily dose.

 

I still get the fleeting back back, some days yes, most days no, but I use this bootleg pill from India and I already have concerns that by the time I split a 20mg tablet in 1/4s that the potency is still there. As if the medication, which does work, is spread evenly through the tablet. If that makes sense. oh I take 5mg 2x day with the stack.

 

in considering Defy's Tri-Amino, it has Ornithine...what is the value there? Can it be added to Gene's "stack" with synergy to the other ingredients?

 

in considering Defy's Tri-Amino, it has Ornithine...what is the value there? Can it be added to Gene's "stack" with synergy to the other ingredients?

I use 1 ml of Tri-Amino each night before bed along with 500 mcg of Sermorelin and love the combo.

 

Does one need to cycle off and on any of the components of the stack? I decided to give l-citrulline a try, and it seems like it helps. Right now, 1 teaspoon with breakfast, and one with dinner, which I think is 3g 2x a day for a total of 6g.

I also decided to lower my dosage of weekly cypionate from 100 mg to 80 mg as my overall T, DHT, and estradiol were shooting up there and I was starting to see blood pressure spikes which were getting harder to control. I think I feel better - more relaxed, not having that feeling of intensity.

Last night my BP was the best I've measured in a while - and I also had frequent morning erections. Not a trend as yet, maybe just an one-time deal - but while I've been consistent as far as the morning erections, this was like continual on and off from about 1:30a on, and it kept waking me up. At one point I was thinking it was a case of priapism as it would not go back now. It was like - I'd wake up - Mr Percy was at attention, and "God, not again...".