Fertility success! Now back to TRT

DRay

Member
Hello all!

Brief update, I recently stopped TRT and got on clomid therapy in hopes to increase fertility to get my wife pregnant. Success! My wife is now 6 weeks pregnant. I have attached links to my previous threads regarding my fertility journey:

Fertility help

Blood results for fertility

So here is my question, what is the appropriate protocol to returning to TRT? Immediately cease the clomid and return to TRT injections? I will also be adding HCG therapy to preserve fertility so I will not have to do this process again. Is there a recommended time to start the HCG as well?

My initial thoughts on restarting TRT:

Cease Clomid
Resume TRT injections 200mg/wk biweekly inj
In two weeks start HCG sq 350 iu m/w/f
Arimidex as needed

Suggestions??
 
Hello all!

Brief update, I recently stopped TRT and got on clomid therapy in hopes to increase fertility to get my wife pregnant. Success! My wife is now 6 weeks pregnant. I have attached links to my previous threads regarding my fertility journey:

Fertility help

Blood results for fertility

So here is my question, what is the appropriate protocol to returning to TRT? Immediately cease the clomid and return to TRT injections? I will also be adding HCG therapy to preserve fertility so I will not have to do this process again. Is there a recommended time to start the HCG as well?

My initial thoughts on restarting TRT:

Cease Clomid
Resume TRT injections 200mg/wk biweekly inj
In two weeks start HCG sq 350 iu m/w/f
Arimidex as needed

Suggestions??
I know this isn’t important since you’re going back to to TRT but how did you feel on the clomid? Worse than TRT? And did you go back to low t symptoms on the clomid ?
 
I know this isn’t important since you’re going back to to TRT but how did you feel on the clomid? Worse than TRT? And did you go back to low t symptoms on the clomid ?

My doctor prescribed me 100mg/day clomid which was a LARGE amount and the side effects were pretty bad. I titrated down to 25mg/day and that was tolerable. I got on clomid solely for the purpose of conception so I was okay with higher dosing and temporarily dealing with negative effects to achieve the outcome of pregnancy quicker.

My Total was in the 600’s on clomid with free T in normal range and E2 on the lower end. Still, I had no libido, fatigue, general dull mood, and I found myself losing strength and endurance as well as major soreness from training. It was easier to gain weight with relatively the same diet as when I was on TRT. So to answer your question, yes, I felt worse than on TRT but it was worth the outcome.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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