Cessation Advice

cowhow

New Member
I'll try to keep this short. A little over a year ago my GP put me TRT at 300mg/wk. This was after an initial blood test and a second to confirm the first. I was left on that dosage for a year until this past November when I had a yearly physical and my labs revealed my testosterone level was over 2300. During that year's time there was not a single blood draw. Not one. So since December my GP has been having panic attacks trying to get my level down. He had lowered my dose to 200mg/wk in December but because of a lack of communication out of his office I was never made aware of that and continued the 300mg dose until March. At that time the dose was lowered from then until now. The GP and I had agreed that at this time we would do more lab work and that was not done. Instead he continues with knee jerk reactions and decided based on lab work that was now 5 months old that he would put me on 125mg every four weeks to bring my test levels down. So, basically I'm going from 1200mg/month to only 125mg/month.

What can I expect basically going cold turkey like this? Because it seems that such a drastic drop like this is about the same as going cold turkey. I mean, 125mg a month is nothing. Any advice is great appreciated. And for the record I'm booking an appointment with a urologist ASAP. And another thing for the record my GP is worthless.
 
The GP and I had agreed that at this time we would do more lab work and that was not done. Instead he continues with knee jerk reactions and decided based on lab work that was now 5 months old that he would put me on 125mg every four weeks to bring my test levels down.
The proposed protocol of 125 mg is typically prescribed as a weekly dosage, not monthly!

The Endocrine Society recommends 75 to 100 mg weekly. It would seem your doctor isn’t even pay attention to the half-life of the medicines he’s prescribing.

Testosterone cypionate has a half-life of 5 to 7 days, so by the end of week two, 75% of the medicine is out of your system, and you’re hypogonadal before the end of week two, with two more weeks to go with abysmally low levels.

Your GP is operating outside his scope of practice.
 
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The proposed protocol of 125 mg is typically prescribed as a weekly dosage, not monthly!

The Endocrine Society recommends 75 to 100 mg weekly. It would seem your doctor isn’t even pay attention to the half-life of the medicines he’s prescribing.

Testosterone cypionate has a half-life of 5 to 7 days, so by the end of week two, 75% of the medicine is out of your system, and you’re hypogonadal before the end of week two, with two more weeks to go with abysmally low levels.

Your GP is operating outside his scope of practice.
Agreed. And what really gets under my skin is my own ignorance at the onset of therapy. I was admittedly naive about TRT and if he had told to go home and drink a gallon of testosterone I probably would have. Because had I known then what I know now I would have asked to be referred to a specialist. Because you are absolutely correct that he is totally outside his scope of practice. As an aside to that I have caught him in other errors of application with medications he has prescribed me. I'm certainly no doctor but I can read and even I know things he doesn't. So, I guess it's on me for making such a poor choice of GPs.
 
I'll try to keep this short. A little over a year ago my GP put me TRT at 300mg/wk. This was after an initial blood test and a second to confirm the first. I was left on that dosage for a year until this past November when I had a yearly physical and my labs revealed my testosterone level was over 2300. During that year's time there was not a single blood draw. Not one. So since December my GP has been having panic attacks trying to get my level down. He had lowered my dose to 200mg/wk in December but because of a lack of communication out of his office I was never made aware of that and continued the 300mg dose until March. At that time the dose was lowered from then until now. The GP and I had agreed that at this time we would do more lab work and that was not done. Instead he continues with knee jerk reactions and decided based on lab work that was now 5 months old that he would put me on 125mg every four weeks to bring my test levels down. So, basically I'm going from 1200mg/month to only 125mg/month.

What can I expect basically going cold turkey like this? Because it seems that such a drastic drop like this is about the same as going cold turkey. I mean, 125mg a month is nothing. Any advice is great appreciated. And for the record I'm booking an appointment with a urologist ASAP. And another thing for the record my GP is worthless.
Glad you made it over here from TID, you will get a lot of good advice here. I already made my comments on TID so I won't repeat.
 
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Predict estradiol, DHT, and free testosterone levels based on total testosterone

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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