Believe progesterone messed me up, need some advice on what might be going on.

Tylurnt

New Member
Ive been on TRT for about 6 months but a few weeks ago decided to try a low dose progesterone to see how it would help anxiety and sleep. I got it from a compounding pharmacy in only 1mg capsules. I took 1-2mg per day for 5 or 6 days and thought it was helping but on the last day, an hour after I took it my anxiety shot up and I just havent felt right since, and its been 2 weeks. My sleep is messed up, im very anxious and lost libido and everything else TRT got for me. Does anyone know what might be happening and how to fix it?
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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