anxiety spike on BPC157?

t_spacemonkey

Well-Known Member
anyone here? trying to exclude reasons. had some bad anxiety weeks in last 2 months.
the only changes I made were BPC157 ipamorelin blend. and a dose of 0.25 semaglutide (never again).
I found random reddit post people having anxiety on both.
 
It seems possible, BPC-157 has some weird effects in some people. I haven't seen anxiety reported as much as anhedonia though, particularly with the oral form.
 
I get bad anxiety from nearly everything.

None whatsoever on BPC from Canlabs
canlabs seems to be on the expensive side, but maybe it is worth it? I've seen it as low for 30usd for 5mg. I also get the sense that peptidesciences is legit (because I had a shitty reaction to semaglutide which matches that of brand name ozempic).
with its short half life BPC157 might be ok to take. I am starting to think that something else caused my issues
 
canlabs seems to be on the expensive side, but maybe it is worth it? I've seen it as low for 30usd for 5mg. I also get the sense that peptidesciences is legit (because I had a shitty reaction to semaglutide which matches that of brand name ozempic).
with its short half life BPC157 might be ok to take. I am starting to think that something else caused my issues

I went for canlabs as they seemed to have the most positive feedback on reddit. I'd rather pay more and be more confident otherwise thats another anxiety trigger! I bought another one off amazon for much less but never used it, didnt get great feedback online.

HGH gave me anxiety and that appears pretty rare, so guess we can all react differently
 
just if anybody is interested. last weekend I 'pulled' my back. i suspect a muscular issue. the pain was even worse the next day and I was like....well, BPC157? I took 2x250mcg injections. 1 subq + 1 IM in the buttocks. the next day....i woke up with 0 pain! absolutely nothing. but my anxiety ramped up definitely. it sort of felt like an all day adrenaline rush. it left in the evening but it was not pleasant. today is a bit better.
I definitely did not anticipate this. i don't think it is in my mind. not sure what the link is. I am reading that BPC157 acts on the brain somehow, but the studies are limited. there is some rat studies that it reverses benzo tolerance in rats somehow. so it must work on the GABA subsystem. also reading that it works on serotonin. there must be some link.
but what is also interesting, that despite my anxiety, i also felt much clearer mentally. as a chronic anxiety sufferer(with good periods as well), maybe my brain needs to go through some sort of reset. I will keep experimenting.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
2
Guests online
1,708
Total visitors
1,710

Latest posts

Back
Top