Recently changed from testogel to tostran as I was getting general anxiety. First week was good but now the anxiety is back very strong ! Was on one sachet of testogel but found halfing the dose helped my anxiety.now on 4 pumps of tostran which gives me a little less testosterone but still anxious !! Was hoping to switch to shots but don't want to risk it if it will make me feel worse ! Have pretty much felt worse on trt than natty except energy and libido is higher !!Bloods in 2 weeks but they only ever check my test level ! So trying to understand what is causing the anxiety !! If anyone can help ! Last bloods came back with rest at 8-10 nmol !Natty was 8 and felt better !
Testosterone & anxiety
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lowe2sucks
Member
testosterone helps a lot with anxiety something is wrong here.. some guys who are hairy get high DHT conversion on topical testosterone (I am one of these) so maybe that's the issue. The only time I have anxiety on TRT is when my e2 gets too low that's when I am anxious 24/7 and one coffee gives me panic attack lol
I am not too hairy but no apply a small amount of gel to scrotum once a week , can't see that it's converting to too much dht. It's interesting you say about low estrogen though ! Something I haven't thought about but not sure I have the symptoms for that . More along the lines of high estrogen but still the symptoms don't fully match that ! Can't touch caffeine at the moment !!! Jittery as it is ! Unfortunately I am not getting the testosterone benefits like most
lowe2sucks
Member
topicals usually result in more dht then injection with same level of total and free t.. if you are high converter to DHT you may actually feel bad and have low e2 symptoms the more testosterone you will use the more pronounced this effect will be.. in this case you will need to use injectable testosterone.
here some low e2 symptoms you may want to look:
dry skin, dry hair, anxiety, social anxiety, urinating more water then you drink, sweating, night sweats, maybe joint pain (not always), fatigue, depression, loss of motivation, brain fog, hot flashes, dehydration, dry lips, loss of libido, ED, nasty smelling sweat (this is when e2 is crashed), panic attacks, mood swings, fat gain (on abdomen with skinny arms and legs) im pretty sure there are more and you don't have to experience all of them.. high e2 shares some of these but depression, brain fog and anxiety are much worse with low e2
here some low e2 symptoms you may want to look:
dry skin, dry hair, anxiety, social anxiety, urinating more water then you drink, sweating, night sweats, maybe joint pain (not always), fatigue, depression, loss of motivation, brain fog, hot flashes, dehydration, dry lips, loss of libido, ED, nasty smelling sweat (this is when e2 is crashed), panic attacks, mood swings, fat gain (on abdomen with skinny arms and legs) im pretty sure there are more and you don't have to experience all of them.. high e2 shares some of these but depression, brain fog and anxiety are much worse with low e2
The ones I highlighted in red are the main symptoms I get from what you describe. Bloods showed I was dehydrated, I get hot in bed and sweat but I have always done that ! Since TRT my weight has not changed ! which suggests no water retention although sometimes my hands feel swollen when I grip stuff also had some acne on arms / shoulders mainly
So symptoms I have are anxiety ( pretty bad ) Constant thinking ( possibly the anxiety ) Low mood , irritable.
other things I have noticed
Sometimes puffy hands, libido is ok and sometimes high ! Looking slightly leaner ( don't go with puffy hands !! ) getting slightly stronger in the gym but not a single Lbs of weight put on or off since TRT 4 months ago.
on testogel my balls shrunk a bit and scrotum was high , felt weird !! but noticed balls seem slightly bigger and hanging lower now on tostran ! also on testogel I had a bought of painful abdomen , increased urination and slow stream along with lightheaded and anxiety. Nipples were real sensitive on testogel and seem ok on tostran . no gyno, no increased body hair, no male pattern baldness
I recent weeks I have noticed that anxiety is greater for me. I think it has something to do with elevated E2 levels. It might not be the case with you though since you just started but then again maybe your body is not used to increase E2 levels. For the first few months (5 months or so) on T my anxiety issues that I had completely diminished.
23TH MAR 2017 11:53 1 MONTH INTO TRT 22 HOURS AFTER 50MG TESTOSTERONE FROM 5 G TESTOGEL
SERUM OESTRADIOL LEVEL 170 pmol/l (0.0 - 172.0 )
SHBG 29 nmol/L ( 13.0 - 90.0 )
FREE ANDROGEN INDEX 31.2 ( 15.0 - 102.0 )
SERUM TESTOSTERONE LEVEL 10.5 nmol ( 6.0 - 27.1 )
SERUM TOTAL PROTEIN LEVEL 75 g/L ( 60.0 - 80.0 )
SERUM ALBUMIN LEVEL 47 g/L (60.0 - 80.0 )
SERUM GLOBULIN LEVEL 28g/L ( 21.0 - 37.0 )
SERUM TOTAL BILIRUBIN LEVEL 16 umol/L ( 0.0 - 20.0 )
SERUM ALANINE AMINOTRANSFERASE LEVEL 24 U/l ( 10.0 - 40.0 )
SERUM ALKALINE PHOSPHATASE LEVEL 61 U/L ( 30.0 - 130.0 )
This was the last time my Estrodial was checked ! I am not expert and have no clue really about hormones but it seems it was at the higher end whilst my t was still at the lower end.
SERUM OESTRADIOL LEVEL 170 pmol/l (0.0 - 172.0 )
SHBG 29 nmol/L ( 13.0 - 90.0 )
FREE ANDROGEN INDEX 31.2 ( 15.0 - 102.0 )
SERUM TESTOSTERONE LEVEL 10.5 nmol ( 6.0 - 27.1 )
SERUM TOTAL PROTEIN LEVEL 75 g/L ( 60.0 - 80.0 )
SERUM ALBUMIN LEVEL 47 g/L (60.0 - 80.0 )
SERUM GLOBULIN LEVEL 28g/L ( 21.0 - 37.0 )
SERUM TOTAL BILIRUBIN LEVEL 16 umol/L ( 0.0 - 20.0 )
SERUM ALANINE AMINOTRANSFERASE LEVEL 24 U/l ( 10.0 - 40.0 )
SERUM ALKALINE PHOSPHATASE LEVEL 61 U/L ( 30.0 - 130.0 )
This was the last time my Estrodial was checked ! I am not expert and have no clue really about hormones but it seems it was at the higher end whilst my t was still at the lower end.
lowe2sucks
Member
your estradiol bloods are not senstinive lc/ms right?
No they are not :-/
lowe2sucks
Member
thing is regular e2 bloodtest doesn't really tell you much.. pretty often it may show different number then sensitive lc/ms.
all of us use sensitive, somebody on this forum even travels from Canada to USA to get his sensitive e2 assay so he knows where his e2 really sits
all of us use sensitive, somebody on this forum even travels from Canada to USA to get his sensitive e2 assay so he knows where his e2 really sits
Unfortunately for me that's not really an option :-/
lowe2sucks
Member
honestly I think your symptoms are little lower then optimal e2 but without proper labwork ofcourse it's just speculation..
especially - quote: So symptoms I have are anxiety ( pretty bad ) Constant thinking ( possibly the anxiety ) Low mood , irritable.
also your total T is "barely" in range so the cause of symptoms also can be that your T dose is not enough
especially - quote: So symptoms I have are anxiety ( pretty bad ) Constant thinking ( possibly the anxiety ) Low mood , irritable.
also your total T is "barely" in range so the cause of symptoms also can be that your T dose is not enough
Like you said my T is low ! If it was higher I am sure it would counteract any negative feelings I am getting . Another thing I have noticed if real shortness of breath ! Will get my blood pressure checked and just hold tight I guess for blood work although I feel the endo is not that clued up !! And even if I switch to shots I am sure I will take on the same sides as he's not helping to clear that up !
If your weight is generally very steady, and you aren't consuming a ton of water(intentionally) I sure would expect to see a few lbs gained with high e2.
At at the beginning of my treatment I wasn't getting full relief from anxiety I was having prior. The dose was a little low. Test was mid range, and e2 was the very low end of the range. Upping the dose solved the problem.
At at the beginning of my treatment I wasn't getting full relief from anxiety I was having prior. The dose was a little low. Test was mid range, and e2 was the very low end of the range. Upping the dose solved the problem.
Just incase anyone wants to know ! My symptoms have eased loads over the last week or so ! The anxiety had got real bad but now nearly all gone !! I started Zma again as it helps me sleep ! Maybe coincidence ! But it's eased since then ! So was it low E2 ? Anxious, sensitive nipples ( not too bad ) low mood constant thinking , delay before peeing. Hands feel swollen when clenched. Now elbows ache a bit. Libido and erection still spot on. Strength in gym going up weight or budged and actually looking good ! Few spots on shoulders. From what I have read this seems like mixed sides !!
So....Blood test coming up, is there anything I should ask endo to check ? Otherwise he will just check the T. If it does turn out to be low T what can be done ?
Also what's people's thoughts on phytoestrogens like green tea ? Can these help with low estrogen and even high estrogen ??
So....Blood test coming up, is there anything I should ask endo to check ? Otherwise he will just check the T. If it does turn out to be low T what can be done ?
Also what's people's thoughts on phytoestrogens like green tea ? Can these help with low estrogen and even high estrogen ??
Vince
Super Moderator
There was a time when I supplement ZMA but when I started supplementing zinc balance I stopped using ZMA. Maybe I should start ZMA again.
Vince
Super Moderator
Does anyone supplement with ZMA?
https://www.excelmale.com/forum/showthread.php?11277-Does-anyone-supplement-with-ZMA
CoastWatcher
Moderator
I would certainly want to know about total and free testosterone, DHT, and estradiol (even with the imperfect test at your disposal). When was your thyroid fully evaluated?
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