pregnenolone

I tried 30mg pregnenolone this morning with breakfast, and about 2 hours later, was hit with such fatigue, I almost had to leave work. It was truly unbearable. Also had some dandelion tea, and I thought that might have been it - but I made some more and it doesn't seem to be the cause. Writing...

If I have natural DHEA-S levels at the top end of the range, sometimes slightly over, is it physiologically impossible for my pregnenolone levels to be low? DHEA can only be made from pregnenolone, correct? So in order for my DHEA to be high, I must have good levels of pregnenolone, right? What...

Is anyone taking Pregnenalone as part of the TRT protocol? do you mind sharing your experience with it? how long have you used it? were you levels low prior to starting supplementing it? what is your dose and how often? are you using capsules or in compounded cream? which one is best

I'm 61, and am not on TRT...yet. Would it be smart to have these other 2 hormones tested since they decline with age?

I've been using Douglas Laboratories brand Preg with great results for months now. 25mg in the morning and 25mg again in the late afternoon. This last week I started taking two pills in the morning instead. To see how I felt with a larger single dose. I like it more. As I was surfing around on...

I wonder if anybody doesn't take dhea and preg while on trt despite being low on labs?

I've been reading lots of information out there on "backfilling pathways" and how supplementing Pregnenolone and DHEA is good in order to supply some of the missing components that TRT will suppress. I am still weighing my options but its looking like HCG may be cost prohibitive at least at this...

Just trying to get a ball park figure of how many men here use pregnenolone in their protocol.

Height: 6ft (Lifetime underweight, never on any psych meds) Motivation (libido mainly): tried cialis Nov 2017 after a year long break and it wasn't working the same, sudden weak erections during porn use Feb 2018 (after 6 years of minimal porn use, nofap with relapses for 6 years), 10%...

Hi all. It was recommended by my Dr that I start 25mg of pregnenolone. Just curious what's a typical starting dose for most, and what have people noticed from it.

Dr. Saya just put me on Test Cyp + HCG and Pregnenolone/DHEA cream (my first consultation). But I forgot to ask him during the consultation if I should start Test / HCG first to feel it out, symptoms wise, before introducing another variable (pregnenolone cream - for low noon cortisol...

MY DHEA has reached a upper limit level and now I just want to supplement one of them. Which one would I benefit most from Pregnenolone or DHEA?

I started back up with Pregnenolone, with some interesting effects. I had taken pregnenolone in the past, (years ago) 50 mg, it seemed to have no effect at that time, but now it does. This is the problem with many supplements/hormones, they are syngeneic with other hormones supplements. I...

I've been on TRT for 6 months now with varying results. My main question is about high DHT levels, erections, and any possible serious side effects. My doctor, who is specializing in HRT for several years now, transitioned from being a surgeon to anti aging medicine. She has more experience...

So long story short, after my last bloodwork I realised that I probably had adrenal issues that had to be addressed. My cortisol was lowish, progesterone was low and so was DHEAS. I felt tired, irritated and I was considering coming off TRT. I crashed my E2 like 4 times this year, mostly because...

My DHEA levels are always at the top end of the normal range. Is this a good indication that my pregnenolone levels are good? I'm curious if there is a positive correlation between DHEA and pregnenolone. Thanks

Nelson Vergel from www.ExcelMale.com explains the benefits of human chorionic gonadotropin (hCG) use in men with low testosterone beyond fertility and testicular atrophy reversal. For more details go to:https://www.excelmale.com/showthread.... and watch https://www.youtube.com/watch?v=0uXoB...

If you have added DHEA, 7-keto DHEA or pregnenolone to your regimen, what has the effect been to (1) your sense of well being and (2) your labs. Thanks !!

Got bloodwork back. Total t is lower than I would have guessed but free t looks good. Estradiol is in line with the addition of arimidex. Prolactin has come down nicely since discontinuing zoloft. DHEA-S and IGF are above range from 50mg DHEA a day. PSA is half of what it was at initiation...

Those of you that have tested Pregnenolone, what are you aiming for level wise? What have you seen with and without supplemental Pregnenolone? I realize this may not be the most accurate or reliable test but seems to be the best we've got currently. Mine just came back at 42 ng/dL with...

" There are various hormones in our bodies, and many of them are made in the adrenal glands. One of them, specifically, is pregnenolone, and it is the one from which all the other adrenal hormones are made - about 150 of them.We've heard of estrogen and testosterone. We've heard of DHEA as the...

Serum Dehydroepiandrosterone, Dehydroepiandrosterone Sulfate, and Pregnenolone Sulfate Concentrations in Patients with Hyperthyroidism and Hypothyroidism by Tagawa, Noriko; Tamanaka, Junko; Fujinami, Aya; Kobayashi, Yoshiharu; Takano, Toru; Fukata, Shuji; Kuma, Kanji; Tada, Hisato; Amino...

Currently on TRT with Defy, doing great. My Pregnenolone level before supplementation was "11", very low. Life Extension recommends between 125-175. I started taking Life Extension Preg, 100mg tabs, once daily. Retested and I'm up to 59. I feel pretty good but I'm considering getting my level up...

I went on Arimidex 1 year ago because I was getting like freaky anxious and crazy emotional. It did help but I have been doing a lot of researching and I'm leaning towards Nelson's take on using an AI. I have been off Arimidex now for 3 months now. I did have some water gain after a few weeks...

A randomized, double-blind, placebo-controlled trial of pregnenolone for bipolar depression by Brown, E Sherwood; Park, John; Marx, Christine E; Hynan, Linda S; Gardner, Claire; Davila, Domingo; Nakamura, Alyson; Sunderajan, Prabha; Lo, Alexander; Holmes, Traci Neuropsychopharmacology. 2014...

Response of serum testosterone and its precursor steroids, SHBG and CBG to anabolic steroid and testosterone self-administration in man. Ruokonen A, et al. J Steroid Biochem. 1985. Abstract The influence of high doses of testosterone and anabolic steroids on testicular endocrine function...

Dr. John Crisler on Super Human Radio about : Pregnenolone , Adrenal fatigue and Anxiety! Discussion about PREGNENOLONE from min. 7.30 !! He is saying that people with adrenal fatigue and anxiety can get better with PREGNENOLONE!! (a study says that people with anxiety have low levels of...