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  1. 1

    TRT question for female

    Hi All! I am female 34 yrs old. I got a full lab testing with hormone panel because I am mainly dealing with low libido and pre-menstrual anxiety. Before my cycle I just go thru a dark phase, I feel im in a weird head space and life is so gloomy. Its cyclical happening almost every month. All...
  2. N

    Controlling Estrogen with Arimidex while pinning once a week?

    Hi guys, A lot happened since my previous thread so I decided to start a new one. It turned out that I have some issues with the SHBG and the more frequent injections I take, the higher it becomes and it's affecting my FreeT a lot. Daily Enanthate injections were the worst, E2D slightly better...
  3. M

    Low cortisol

    I have been on trt for many years, last few years just not feeling well, thought it was my trt dose or estrogen, ran many blood tests and found out recently my cortisol has been consistently low, went to the Hospital and they ran the Cortrosyn stimulation test on me and my adrenals did not...
  4. S

    The best method of dialling in Aromasin dosage

    Dialling in your AI dosage can feel a bit like walking a tight rope, especially with Aromasin as crashing your E2 with it is more unforgiving than with Arimidex due to Aromasin's suicidal nature. A study Pharmacokinetics and Dose Finding of a Potent Aromatase Inhibitor, Aromasin (Exemestane)...
  5. N

    Controlling Estrogen with Arimidex?

    Hi guys, I was on a 500mg test-e cycle for 12 weeks and I have decided to continue on a TRT from now on. I switched to 125mg for a few weeks but I was feeling down, slept like 12 hours a day so I switched to 150mg. It's been a week, I'm feeling great, but I'm starting to feel gyno. I was...
  6. B

    My solution for high estrogen after years of troubleshooting

    This is a bit wordy but I want to share what is working for me take get estrogen under control. I've been on TRT for over 6 years and estrogen has been my challenge. If you have battled this issue while on TRT, maybe this will work for you. And maybe I'm a slow learner and most of solving the...
  7. K.pietera

    Iron overload

    Hi there , So my blood results came back and you can see them in the attachment. As you all can see my serum iron levels are way to high also my ferritin is to much. I tought it was strange because I don't consume red meat that often...( 2 times a week) But I think I have found an awnser...
  8. L

    Dealing with finasteride rebound?

    Hello lads. I stopped taking fin a while back (weaned off) but seem to be dealing with rebound effects almost a year later and not sure where to turn. I saw an endo on the UK/NHS health service but they were rather clueless and gave me tame suggestions of eating more vegetables etc which I...
  9. M

    My dose has been too high?

    Try and keep this short...5 years ago felt bad, Dr put me on 100 mg of Test cyp 1x a week, did ok for a while, HCT HGB got too high, told to donate every 4 months, still didn't feel right, test levels were great, high in fact around 1000, after another year still felt rough (Yes tested for...
  10. B

    Having a rough time since I lowered my Test dose....

    I lowered my dose from 120mg (was on for over a year) slowly down to 90mg a week over a few months, just recently (2 weeks ago) split it into 3 times a week MWF 30 mgs per. SInce then I feel more emotional, depressed, anxious, my nipples are really sore, I am more TIRED and ACHY all over...
  11. Drug350

    Need Help Suggestions For My Numbers - Advice Appreciated

    I'll try to condense this. Many already know my story. 54 yrs old. Started TRT in late November as my repeated totals were all below 200 NGDL. I was put on 100 MG's Testosterone Cypionate weekly. First three weeks I felt amazing. Morning wood, great erections, libido off the charts, great sleep...
  12. K

    In Desperate Need for Advice | 8 months on TRT

    Hello, been lingering on this forum for some time, just now looking to get more involved. I am a 21 y/o male, been on TRT for 8 months and have had little success. I've had a couple different protocols and personally suspect estrogen to be causing TRT to fail me. So what I'm asking: Does...
  13. R

    How can I raise my SHBG fast?

    I need help. I am on TRT for two years. Since last year my experience was being extreme bad. Anxious and started to have ED. My SHGB is 7 now. Yes, 7. I need to raise it really fast. I am not diabetic nor have metabolic sindrome. I am very atletic and slim. It because of TRT and for some reason...
  14. D

    Blood Work opinion. Estrogen and Total T - Anxiety

    Lab TESTOSTERONE, TOTAL, MS 1174 High range - 250-1100 ng/dL TESTOSTERONE, FREE 284.1 High range - 35.0-155.0 pg/mL ESTRADIOL,ULTRASENSITIVE, LC/MS 69 High range - < OR = 29 pg/mL EZ Current symptoms. Cant lose belly fat High Anxiety that I haven't felt...
  15. S

    Hot flashes are unlikely to be a symptom of increasing or increased E2, and more likely to be a symptom of decreases in E2 levels or low E2.

    After reading up a ton of literature on Estrogen effects on males, there's really a whole bunch of realisations about how extremely useful it is in male function and consequently how misunderstood and mishandled it is by men or TRT clinics. I'm glad Nelson seems to have a much better...
  16. K

    D-chiro-inositol raises testosterone significantly

    This study confirms that D-chiro-inositol raises Testosterone significantly and lowers E2 and Estrone : Why is this not talked about anywhere ? Is there something wrong with the study ? Am I missing something ?
  17. F

    Tetracyclines and Estrogen

    More and more, I believe I fall into the camp of those that feels better with E2 in the normal (non trt) range. Supposedly tetracyclines can raise estrogen levels. I know nothing about the mechanism. But, on two occasions, I have developed symptoms I believe to be E2 related while on Sarecycline...
  18. S

    Accidentally took a megadose of Estradiol in place of Testosterone

    I've been very foggy after dealing with a thiamine paradox reaction that won't go away (long story - I have CFS, so used thiamine to treat it). Hence this morning, instead of TRT I pinned Estradiol Valerate without realising. The dose was 20mg - which is roughly equivalent to 40 oral 2mg...
  19. Z

    FSH level on transdermal estrogen

    HRT regime Transdermal estrogen, Oestrogel, 2 pumps each morning, a total of 1500 micrograms Half the month also take Utrogestan (progesterone) 2 per night, a total of 200mg 50-year-old female, a few months on HRT, still having periods. Test Results Test was in the morning, during the...
  20. T

    I seem to disproportionately aromatize from alcohol - any suggestions?

    On TRT I'm not able to drink alcohol with what I would describe as an estrogen hangover. I haven't blood tested, but I have been on clomid before so feel like I can tell my E2 gets too high. My levels on TRT around 600 trough with EOD injections, with a good free T for that level. I also have a...
  21. T

    Experimenting with Arimidex when drinking alcohol

    I have been on TRT for 9 months (age 28), but have found that it doesn't mix with alcohol well. I've only drunk 3 times, but each time I get what feels like an estrogen hangover that lasts for a couple of days. I don't have blood tests to prove this, but when I drink I get acute bloating, acne...
  22. D

    Do I really have to take an AI like Arimidex during TRT? I think it makes me miserable.

    Given my estrogen levels below - what would happen if I stopped taking my Arimidex 2mg / week (taken for about like 10 months)?? I only ask this because many people on this forum say very nasty things about Arimidex... Is the only real possible side effect really just gynecomastia? P.S. - This...
  23. S

    Headaches TRT

    Just wondering if anyone gets headaches on there protocol. I have mild sinus disease , and I'm guessing estrogen may be causing it to flare up worse. I am on 150mg of enthenate a week and 0.5 of armidex. Any advice on how to tackle this would be much appreciated
  24. P

    Are E2 Tests Useless??

    I’m sure many here have seen a lot of the videos from the TRT Optimization guys, and I will say they put out a lot of good information. One thing I’ve wondered about lately is the claim that it’s pointless to check E2 due it being a paracrine hormone. I understand the desire to to move away from...
  25. D


    Funny, one website says things like cruciferous vegetables, soy, herbs etc lower estrogens, the next website assures one that these same things raise estrogens. One says lowers cancer risks, Next says raises cancer risks. Surely there's a way to basically test this sort of thing?
  26. J

    Anastrozole effects in the brain

    (Moving this to a new thread since it is a different topic) I am harping on this as I was doing pretty well on TRT with less than 100mg Testosterone Cypionate once a week plus 250IU HCG twice a week. Strong libido, good erections, etc. At that time, if I took 5mg cialis I could feel the effect...
  27. nodoctor

    High: Lipids, CO2, PH, E, creatine kinase, hct, low:Vit D and more!

    First of all--thanks for the amazing and science/data driven advice I've received from you guys! I totally agree with treating symptoms not labs, but I've got some results that I think warrant action. Latest labs attached. Any help or questions much appreciated! General background: strict...
  28. C

    Skin issues while on testosterone?

    Has anyone experienced eczema like skin issues while on TRT? I don't mean injection site issues like redness and inflammation but systemic hive like, extremely itchy raised lesions on the back, chest, right and left flank. I have been off TRT for a few months now and the issue has increased. The...
  29. T

    Estrogen Symptoms PLEASE HELP

    Here we go - I’m off on an estrogen trip again. I am getting labs tomorrow, but results have been taking 10-14 days. I don‘t think I can remain this miserable for that long. I am on .1 Enanthate daily, and .125 Anastrozole every other day. I was taking .125 every 3 days, and my e2 was at 31, so...
  30. T

    4 weeks off TRT - still needing AI to combat E2 anxiety

    Hey guys, Looking to get some input. I am 34 years old, low SHBG (17-19), 160lb, athletic build. I've spent the last year experimenting different protocols to find one where I feel good/normal. Surprisingly, the closest I can get to feeling fine is on a single injection frequency, with AI every...
  31. M

    Could progesterone use crash estrogen or cause joint pain?

    Hello, for the past 2 weeks I’ve been using progesterone cream, one pump scrotal application per day. Over this weekend I started to notice my joints were achy, felt sort of dry, popping a bit. I’ve actually been feeling pretty good (libido and mentally) but thinking I may have overdone it with...
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