estradiol

I had a question regarding the side effects of AI’a and can’t seem to find a consistent consensus regarding side effects. I am aware that there can be side effects from the usage of AIs, from my understanding the sides are from crashing estradiol to an unhealthy level. Most of the negatives...

So, funny story. (For those that aren’t me lol) I keep my Arimidex on the left, viagra on the right. Evidently during cleaning my wife swapped them not knowing. I took 3 and thought man, I’m getting low. (I wasn’t but hindsight - wrong bottle) so I’m aware the dosage for full blown cancer...

I have been on TRT for 2.5 years and have had textbook levels - TT around 1000, FT in the 20's, SHBG fluctuates between 45-50 and E2 typically matches SHBG. I have never had any E2 symptoms though I will admit that my regimen would create an E2 nightmare for most - test cyp 60 mg every 3.5, HCG...

We know that men in the modern age are bombarded with estrogens and estrogenic chemicals from every direction in food, water, medications, environment, and products. Which leads me to wonder: what is actually an acceptable testosterone and estrogen level for men? Testosterone levels have been...

I often have a few surprises in my blood test results. Today's surprise was estradiol. I attached the last couple of blood test results, one from 1-7-2020 and one from 11/15/2019. Today, the surprise was pretty low E2 levels of 8.9 pg/mpwith a Total T of 650. (I tend to do blood test just...

Before I started testosterone my erections were weak. Viagra was my best friend. When I started injecting testosterone my erections and libido increased. But is there a way to make it better? I keep hearing people say that high estradiol increases libido/erections. Other places say high...

I was on propionate for a year till I got tired of it so talked to my doctor and now my protocol is Cypionate 32mg EOD plus 300IU of HCG once a week. Doctor suggested EOD to keep my levels stable because I'm not using much HCG now. I wonder if this is really necessary. Twice a week is more...

Been on TRT for about 10-12 weeks now. Started off great, but now feel like death. Insomnia, terrible libido, freezing cold, joint pain, etc. My guess is due to my low estrogen levels, which I had confirmed. On my recent blood work, my free T was slightly over normal range, as was my total T...

I’m 57 yr male, in great shape, lift weights 3 times weekly. I’ve been on clomid self prescribed hrt for 4 years. 25mg 4 days a week. Last time I had my testosterone checked it came back over 1500 so the free was inaccurate. Estrodiol was 64.9. I have felt really good. I decided to start using...

I'm just wondering how many of you feel better on the higher end, like 30-40, 40+, or even higher. And also what your total T and shbg are. I want to run higher levels of test for my trt and also avoid using an AI but I kind of fear the higher estrogen mainly for potential libido and ED sides...

Seeking advice on my protocol and go forward recommendations given the following: Just started TRT 4 weeks ago, did a baseline blood work on T & E: TT = 454 FT = 4.7 E = 17.2 My protocol: 100mg T-cyp 2 times per week (Mon & Thurs). 200mg total for the week Plan to add HCG and AI's (as...

What is the best starting protocol for a 34 y/o with total T between 300-500, high SHBG, and wanting to have kids within the next 1-3yrs? Background: 34 y/o, 6'3", 203lbs, <10%bf, workout a lot One doc recommend 50mg Clomid and HCG. After reading here it seems clomid isn't a great choice for...

So far we’ve only looked at splitting the dose equally vs taking the full dose at 1 shot...but what if we split 100mg, for example into 60/40mg or 70/30mg? Could that provide a little more e2 but still stable enough total T levels without an increase in Hematocrit? Anyone have any thoughts...

not talking about the blood test, I know I can get that, but a calculator similar to the one used to calculate free testosterone. If so, can anyone post the link? I have tried to find it with no luck. I have low SHBG and my E2 needs to be managed at very low levels, so this tool may be useful...

Hi, I am a low SHBG guy who has managed to increased it to around 14-15 while on TRT. It has been years trying to fine tune my protocol and after several lab tests and anaztrozole dosing, I have confirmed I feel best when my E2 is around 10ish. At that level my libido is very good, no bloating...

Recently diagnosed with Low Testosterone. I'm doing my best to get into the High Normal Range of Testosterone with the Estradiol in the normal range. It's very hard to do without the use of Anastrozole (in which even the lowest dose makes me sick.) My mind gets very foggy and unstable even...

I just had some labs done - my Seum Estrone came back high at 126! The range is 15-65. Meanwhile, my Estradiol is also high at 44.2 (range is 7-42). What the heck is the difference between Estrone and Estradiol? I'm on hCG mono - I had crashed my E by taking Letro, so I've cut back on that to...

Hi everyone: My estradiol is high at 65 pg/ml. I am gonna see my endo asap. Should I ask him to start me on aromatase inhibitor meds?? I am very concerned about it. Thanks

All, I love how aromasin (exemestane) makes me feel, much more than arimidex (anastrazole). Anastrazole feels harsh and slightly poisonous, where exemestane feels smooth and mild. I have been using it on and off for years as a stand-alone, to both increase testosterone, lower SHBG and control...

SOOO, I added HCG to my TRT the end of may 2019;.. the first 4 weeks was 500iu a week .....i wasnst sure how my body was going to react .... so i jumped it up to 800iu the last 2 weeks of the first 6 weeks of it before my first Labs to check E2 and hema it was fine... so I jumped it up to...

30 y/o male - good health/ diet/ sleep etc. New here and no former TRT/ AAS use. Key results from two different blood tests (5 weeks apart) are below. Today I went and saw a private hormone specialist (leger clinic - Dr Savage) who advised that I may benefit from TRT due to relatively low Free...

I have been reading this forum obsessively for the last few weeks. What an incredible group of guys you all are. I have only been on TRT for about 3 months so I am figuring things out. At 2 months my bloodwork looked good and I decided to add HCG because the doc recommended it. So I have...

I searched and I can't seem to get a answer. Question with LOW SEX HORMONE BINDING GLOBULIN = 8 Range: 10-50 Will Everyday or Every Other Day injections work to raise or lower E2 and bring SHBG up. I was under the impression that ED injections will actually cause E2 to be higher and bring up...

For those who don’t know my history, I have a consistent lowish estrogen problem because I can’t raise my testosterone dose high enough to aromatize enough e2, due to erythrocytosis. Using 60mg twice per week right now and that has my Hemoglobin at 17 and hematocrit at 50.9 so far. Going to...

Adding supplemental scrotal T cream seems to be the trend lately, and personally I've definitely seen some benefit. Based on information from some doctors and other board members it seems the DHT:E2 ratio is improved, which gives a better sense of well being and libido. However, couldn't the...

I've struggled with estrogen management since I began trt about a year ago. I've always injected Sub-Q and the research supports T levels through Sub-Q. However, at my Wit's end I decided to begin injecting in my deltoid about 2 weeks ago. It's really made a big difference in my estrogen side...

Hey guys, can high e2 cause anxiety? I know it can cause one to be more emotional which I have been and have been crying but my anxiety is through the roof!!! I am prone to anxiety and have been since I was little. There is alot of big changes going on in my life....bought a new house and...

GUYS. I need some advice HCG is all new to me... 1. Sorry this is so long , just trying to get all the info in here. so please glance at it 2. I have just Gotten a prescription for HCG (Pregnyl ) after almost 3 years on TRT ..50mg 2x a week I got the arimidex as well 3. I have not...

I was on TRT for about 18 months. Decided to stop and attempt a restart using toremifene. The restart was a success! I haven’t had any injection or any SERM since October 2018. My current labs are: Total T: 694 E2: 12.8 I’m concerned that my E2 is too low. Is it actually too low? Is this...

When I inject test cyp, I know levels rise then fall a bit several days later. What happens to E2? Say I inject twice a week and take .125 anastrozole each time. Does my E2 drop the first day or two due to the anastrozole then rise on day 3? I guess I am asking in this case if test and e2...

I was looking for something else, when I came across this study: Estradiol stimulates cortisol production by adrenal cells in estrogen-dependent primary adrenocortical nodular dysplasia. - PubMed - NCBI It's an old study and it has been performed on a single patient with ACTH-independent...