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  1. M

    TMAO finally conquered

    To cut to the quick: Only when I completely eliminated all exogenous oral supplementation of both choline and carnitine and started using injectable forms of both in the last 45 days did my TMAO levels finally normalize. Even cutting back on oral form did little to change my levels. Not only...
  2. M

    Normal creatine kinase enzymes, but moderately elevated total CK

    Those more familiar with CK. Results below. Liver and kidney markers all within range. How can totals CK be elevated if the CK enzymes are within range? Perhaps a high protein diet and dehydration from fasting for the test can cause elevated total but normal enzymes? If it was from heavy...
  3. M

    Super low iron, ferritin, CBC markers off, elevated PSA

    Friend of mine on 200mg/week test cyp (50mg eod subq) + nandrolone 50mg/week. Age: 55. Cannot understand why his iron/ferritin and CBC markers are drastically off, but suspect it has to do with his HRT. He is negative for any internal bleeding and claims to be asymptomatic Also, his PSA...
  4. M

    Anyone have gallbladder issues?

    An abdominal ultrasound showed an incidental finding of gallbladder sludge and trace gallstones. Followed up with a HIDA scan done with ejection fraction. EF was only 25%. Normal is 35% and above. Diagnosis: biliary dyskinesia which means not enough bile is able to exit the gallbladder and...
  5. M

    Anyone have Covid and measure their coagulation/clotting factors?

    I am trying to makes sense from my latest bloodwork. My main concern is whether these elevations (see attached) are likely due to the Covid infection I had 30 days prior to the blood draw and not due to my 3 mo.of 25mg/day enclomiphene regimen. Of note: I had a clot of unknown original form in...
  6. M

    FIRST MONTH on ENCLOMIPHENE – NO CHANGE

    Started on 12.5mg/day on July 26. Rx from Empower Pharmacy. Took my dose first thing in the morning with water only. After 27 days, no change at all in total (443), free or bioavailable T nor any change in E2, FSH/LH. I also expected to see a drop in IGF-1 since enclomiphene is supposed to...
  7. M

    Severe Diastasis Recti + multiple hernias confirmed

    Update: I've come a long way since my initial post when I had no clue what was going on with my abdomen. Thanks to BigTex for calling it out at the get go. I finally found my answers and hopefully the expert surgeon to correct these defects. I didn't want to report back until I had my...
  8. M

    Blood clots and Enclomiphene?

    https://support.maximustribe.com/en/articles/6325759-are-blood-clots-a-side-effect-of-enclomiphene-king-protocol Since it is the zuclomiphene isomer in clomid that accounts for many of the unwanted side effects, including blood clots (as detailed in this paper), why would there even be a...
  9. M

    Why low ferritin, high normal iron, saturation?

    Can anyone hack these values and tell me how one can continue to have normal-high serum iron levels, occasional high % sat, low normal hct/hgb/rbcs and low normal ferritin? Not on TRT, negative for any internal bleeding. I do seem to fit the description of "iron avidity" as described here, but...
  10. M

    Anyone taking PCSK9 inhibitors (i.e. Repatha)?

    I have a scrip for Repatha but haven't yet started. Covered by insurance so cost not an issue. Was concerned that LDL would go too low and cause issues. Also, side effects. Read that it can cause hyperglycemia (diabetes). Any input would be greatly appreciated.
  11. M

    WORSE CARPAL TUNNEL-TRIGGER FINGER-PAIN & SWELLING

    For those with experience with GH, peptides, IGF-1... Some quick background: First signs of trigger finger, carpal/cubital tunnel (numbness) started in early 2019. Had TF surgery (percutaneous release) in June, 2020 - successful outcome. Slow progression in a few other digits since, but no...
  12. M

    TRIGGER FINGER is OUT OF HAND (no pun intended)

    Prior post: https://www.excelmale.com/forum/threads/anyone-have-experience-with-trigger-finger.21215/#post-180384 The warning signs started in 2019. Had first surgery in 2020. Thought it was a one and done. 3 years later and I am plagued with the worst trigger finger and pain in the rest of my...
  13. M

    CCTA vs CAC scan to detect atherogenic plaque

    Has anyone done a CAC scan and CCTA and observed a wide difference in results? My recent CCTA (coronary computed tomography angiography; see below) showed "no evidence of coronary atherosclerotic plaques or coronary artery stenosis". This is in direct contrast to the CAC scan I had done in 2021...
  14. M

    PEPTIDE RESULTS IN: IGF-1, testosterone, etc.

    Big n-1 results update. With all the gym bros telling me for the last 10 years that GH secretatgogue peptides are a scam and a waste of $$$$ - and that good ol' GH is superior and the only way to go - - - Let me preface this post by saying that these peptides do work. I repeat. THESE PEPTIDES...
  15. M

    Carpal tunnel symptoms and peptides

    Anybody experience carpal tunnel syndrome symptoms (i.e. numbness in index finger, thumb and middle fingers) and body aches from GH peptides (tesamorelin, ipamorelin, etc.) especially when waking? I understand that CTS is a very common side effect with GH itself. What did you do to remedy it? I...
  16. M

    Lean mass loss on GLP-1 receptor agonists: a downside of the “miracle drugs”

    Has anyone done a DEXA scan before and during use of any GLP-1 agonists (semaglutide, tizepatide) to assess body composition? In Peter Attia's recent blog, he eludes to the fact the GLP-1 agonists can cause loss of lean mass (in addition to fat loss), of particular concern in non-obese persons...
  17. M

    Bubble gut – VAT, SAT, both - or something else

    Somehow I've developed a distended abdomen/hard belly and umbilical hernia (inverted navel) similar to the attached photo. I cannot tell if it's visceral adipose tissue (VAT) or subcutaneous abdominal adipose tissue (SAT) - perhaps both. I cannot see my abs even when I flex so there's SAT. It's...
  18. M

    Anyone using T2 as a fat burner?

    A few doctors have touted the little-known thyroid hormone T2 to be used to help burn brown fat. Since there is only a tiny amount (8mg) in my NDT, I was thinking of adding it for the purported benefits...
  19. M

    TOO MUCH T3 FROM NDT = JOINT PAIN?

    Latest labs (last dose of 2.50 grains (162.50mg) NDT taken only about 6h prior to draw): TSH:1.23 ref range: 0.450-4.500uIU/mL FT3: 5.00 ref range: 2.0-4.4pg/mL FT4: 1.60 ref range: 0.82-1.77ng/dL Anyone notice that too much T3 from desiccated thyroid causes a flareup in joint pain? Is a 5.0...
  20. M

    GH SECRETAGOGUE PEPTIDES & IGF-1

    Anyone have data showing that if one's natural IGF-1 level is high normal for one's age as in my case (see below), would GHRH/GHRP peptides be contraindicated since they raise IGF-1 over time? The concern is not as bad as with straight GH, but is still an issue for long-term (cancer, CV disease...
  21. M

    Upped dose of NDT and my TSH went up!

    How is it possible that I can take a higher dose of NDT and do my labs at the same time as prior and come out with lower TSH and T3? Prior labs (NDT dose @ 2.00 grains - 130mg): TSH: 2.03 FT3: 3.70 FT4:1.40 Current labs: (NDT dose @ 2.25 grains - 146.25mg): TSH: 3.29 FT3: 3.5 FT4: 1.5 No...
  22. M

    METFORMIN - no change in glucose readings

    I've been on Metformin for a month now. I am not diabetic and am taking it for the anti-aging and cardiovascular benefits, etc. I eat the same diet (low carb). I have not seen any difference in my fasting or postprandial readings. Same issue with taking berberine (which I still take with...
  23. M

    Has anyone tried Tirzepatide (Mounjaro) - supposedly more effective than Semaglutide

    The new GLP-1 + GIP all-in-one, Mounjaro. More here.
  24. M

    Defy shipping costs

    Has anyone been able to find an alternative supplier that doesn't overcharge for shipping? I realize they are not the actual pharmacy, but charging as much or more than the cost of the item itself is insane. That is on top of an already marked up full retail price item.
  25. M

    EXTENDED-RELEASE NIACIN & GLUCOSE LEVELS

    Anyone notice impact on fasting and post-prandial glucose levels and a1c from taking high-dose ER niacin to manage lipids? I was on 1.5g per day and increased to 2g per day and now I'm noticing glucose levels about 10 points higher. Wondering if this will subside over time. I know some are...
  26. M

    ADVANCED LIPIDOLOGY PRACTITIONER

    Although I am a member of Dr. Davis's Undoctored Inner Circle group, I feel the need for more extensive intervention from a live coach/practitioner. ER-niacin + other lipid-lowering supps do definitely work and perhaps the LC diet, but it's the APOB, pattern B and small LDL that continue to be...
  27. M

    FAT LOSS DIFFICULTY - PART II

    Original thread here. Updated observations: • Only positive out of all the slow gain in weight/bf is in strength increase of between 20-25% • Workouts just keep me toned at this point, slow to recomp (add or retain LBM/losing fat) • Calorie restriction/deficit does work – am losing...
  28. M

    Has anyone seen low HDL while on DHEA or pregnenolone?

    The low HDL dilemma (lowest ever @ 39) - labs here. As you can see, a dramatic decrease in total cholesterol and LDL-C on my standard lipid test from prior labs. But why did my HDL sink along with the other lipid markers? I check all the boxes for doing things to raise it (fish oil, niacin...
  29. M

    Anyone done a GH stimulation test?

    Has anyone done a GH stimulation test to determine pituitary response before starting GH secretagogue peptides? Some of us may have empty sellas that we may not even be aware of and that may or may not affect pituitary function in which GH secretagogues will be a waste of money.
  30. M

    Standing vs seated lateral raise machine

    As far as lateral movement with a machine - what do you think would be best for deltoid hypertrophy? Seated: Standing:
  31. M

    Revisiting the digit ratio (2D:4D) and TRT

    Is the digit ratio an indicator to personal optimal testosterone level? So, I have the unfortunate higher digit ratio, meaning I had reduced prenatal androgen exposure. A blessing when it comes to BPH and a curse when it comes to everything else. At the end of the day, does it have any...
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