Really Need Help - Low Estrodial

Johnny Test

Active Member
Hey everyone. I’ve been on TRT for years. I’m dialed in at 902 ng/dl. Two shots per week (60mg on Monday and 60mg on Thursday for a total of 120mg). Done Sub-Q

I’ve had three different Estrodial blood tests and they have come back 1 pg/ml, 0.6 pg/ml and 0.8 pg/ml. How is this possible? I’m not on any aromatase inhibitor. I do take Calcium D-Glucarate daily though. What do you make of this?

Am I reading unit conversion wrong or something?
 
This is the info from tests. Has to be wrong right guys?

ESTRADIOL FREE​

pg/mL
Value
0.8

INTERPRETIVE INFORMATION: Estradiol, Free by Dialysis No reference intervals have been established for prepubertal females or for cisgender males. For a complete set of all established reference intervals, refer to ltd.aruplab.com/Tests/Pub/2006160. This test was developed and its performance characteristics determined by ARUP Laboratories. It has not been cleared or approved by the US Food and Drug Administration. This test was performed in a CLIA certified laboratory and is intended for clinical purposes. Performed By: ARUP Laboratories 500 Chipeta Way Salt Lake City, UT 84108
 
What’s the range? And ur strictly testing for free E2, not total E2 as well?

what company do u get ur labs done through?

I can’t remember off the top of my head which company I used to get free E2 done at. It was either labcorp or quest diagnostics. Probably labcorp back then. But I used to get free E2 tested all the time. The range was (0.2-1.5). If that’s the same range for ur free E2 tests, then ur not low at all. Ur actually perfectly within range
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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