Efficacy of same site injections

Building up scar tissue doing:
  • 25 gauge x 1" needle
  • glutes, alternating
  • 2x per week
So I switched to:
  • 27 gauge 1/2" needle
  • delts, thighs, alternating
  • 2x per week
Do you think TRT efficacy will increase by not injecting into the same spot all of the time (scar tissue)? Please don't respond with "The only way to find out is with a blood test". I plan on doing that. I'm curious of other people's experiences.
 
I do daily injections so I have six areas I inject. I inject in my VG, sub q in love handles and shoulders..

 
Been doing IM injections now for 42 years now. I have so much scar tissue that I can bend a 27g. Have you tried sub-q? I use a 31g insulin syringe, warm the test cyp in the microwave for 10 seconds and do 35mg x 2 and 30mg x 1 every 10 days. I have a friend that does 10mg every day.

 
Building up scar tissue doing:
  • 25 gauge x 1" needle
  • glutes, alternating
  • 2x per week
So I switched to:
  • 27 gauge 1/2" needle
  • delts, thighs, alternating
  • 2x per week
Do you think TRT efficacy will increase by not injecting into the same spot all of the time (scar tissue)? Please don't respond with "The only way to find out is with a blood test". I plan on doing that. I'm curious of other people's experiences.

Forget the 25s.

Good to alternate injection sites.

Even then trauma/scar tissue will be minimal when using a 27-29G insulin syringe injecting strictly IM let alone 30-31G strictly sub-q.

Most on trt are injecting IM or sub-q using LDS fixed insulin syringes 27-31G various needle lengths.
 
I was going to start a new thread but I'll just ask for opinions here.

I pin .32 ml EOD and alternate between the glutes and delts using a 1/2" 29 G needle. My problem is that I often have a hard time pushing the plunger down when I inject the delts. Sometimes there's so much resistance that I have to find a different spot because I literally cannot depress the plunger. Both shoulders have permeant lumps in the area I inject. Is this scare tissue and is that why I'm having difficulty? Can I break down the scare tissue?
 

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⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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