Tadalafil (Cialis) minimum effective dose...

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Sergel

Member
Excuse my enthusiasm, I just had my first Cialis experience... I am like a kid this morning... darn...

TLDR: I only took 2 to 2.5 mg of Cialis at 1pm, made love at 11pm and had a hell of a stiffie and great orgasm... Any one else get by with such a small dose...

Now the full story:

But, darn, such a small dose being so efficient? On trt (100 mg / week, 50mg e3.5d, enanthate) I feel real good. Low SHBG makes my free T high at that dose... so with T I had to learn the hard way that less is better for me... I have good morning wood most mornings, am 63 ...

Now in discussing erection with my doc, he suggested Cialis... at 63, I though maybe it was time... although I could have an erection during intercourse, the quality or durability of it often fell short (excuse the pun)... many times I could not get to climax, I would start with a stiffie, play... it would go away, come back, go away, come back... and had a terrible time climaxing... like I was anorgasmic... quite frustrating.

So he suggested 20mg on demand... but having read here a lot about Tadalafil, I asked him to give me the 5mg variety so I could modulate... and try daily ... basically I like to experiment. But being allergic to quite a few things, I wanted to try out a small dose (I took the small half of a 5mg split in two)... question to see if the congestion, headaches and all those aweful things they plaster all over the internet would show their heads.... I did not expect anything from such a small dose (probably between 2 and 2.5 mg... !)

So my girlfriend came to dinner, I had no boose... (I like wine a lot...) ... and we went to bed...Oh boy... My girlfriend was not in on the secret yet... lol We were basically just kissing and she said, oh! Look at this! ... I was as surprized as her...

Damn, I did not have an erection like that in my 20s ... It lasted from arousal to orgasm...like I was 20 again! Holy moly Batman... that was something... and the orgasm was so intense, sensitivity was good... damn... Again, excuse my enthusiasm... Tadalafil newbie here...

My question is: ... Am I hyper sensitive to this thing? Are other guys getting good effect from such a small dose? Will I build a resistance? Anyone else using 2.5mg on demand and getting results?
 
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Golfboy307

Active Member
There might be a bit of the placebo factor at play. That is a really low dose to have that dramatic effect. But, hey, its the result that counts! If you really do respond that well, PDE-5 inhibitors will be great to have in your arsenal. The lower the better so their effectiveness won't wane. I take 2.5 -3mg daily with generally good results. But it doesn't work on demand for me like that. (Viagra does..)
 

Sergel

Member
That's what I thought too... I was not expecting anything... but it was surnatural... if it's placebo, I need to find the place in my head where I was... but I was thinking of 2.5 daily... I will continue to experiment, but even morning wood this morning was a little persistant... I was just surprized by my response...

I am fully opened to the possibility that it was all in my head... but somehow think it was too much to be natural... at least unseen since my 20s
 

Sergel

Member
Wow, I found the reviews on Drugs.com ... for Cialis... Seems like many are like me, one 2.5mg the get hard for a couple of days... So I guess I am not that special! ... lol A lot of enthusiasm in those reviews... really a wonder pill, I am truly flabergasted.

 

madman

Super Moderator
Excuse my enthusiasm, I just had my first Cialis experience... I am like a kid this morning... darn...

TLDR: I only took 2 to 2.5 mg of Cialis at 1pm, made love at 11pm and had a hell of a stiffie and great orgasm... Any one else get by with such a small dose...

Now the full story:

But, darn, such a small dose being so efficient? On trt (100 mg / week, 50mg e3.5d, enanthate) I feel real good. Low SHBG makes my free T high at that dose... so with T I had to learn the hard way that less is better for me... I have good morning wood most mornings, am 63 ...

Now in discussing erection with my doc, he suggested Cialis... at 63, I though maybe it was time... although I could have an erection during intercourse, the quality or durability of it often fell short (excuse the pun)... many times I could not get to climax, I would start with a stiffie, play... it would go away, come back, go away, come back... and had a terrible time climaxing... like I was anorgasmic... quite frustrating.

So he suggested 20mg on demand... but having read here a lot about Tadalafil, I asked him to give me the 5mg variety so I could modulate... and try daily ... basically I like to experiment. But being allergic to quite a few things, I wanted to try out a small dose (I took the small half of a 5mg split in two)... question to see if the congestion, headaches and all those aweful things they plaster all over the internet would show their heads.... I did not expect anything from such a small dose (probably between 2 and 2.5 mg... !)

So my girlfriend came to dinner, I had no boose... (I like wine a lot...) ... and we went to bed...Oh boy... My girlfriend was not in on the secret yet... lol We were basically just kissing and she said, oh! Look at this! ... I was as surprized as her...

Damn, I did not have an erection like that in my 20s ... It lasted from arousal to orgasm...like I was 20 again! Holy moly Batman... that was something... and the orgasm was so intense, sensitivity was good... damn... Again, excuse my enthusiasm... Tadalafil newbie here...

My question is: ... Am I hyper sensitive to this thing? Are other guys getting good effect from such a small dose? Will I build a resistance? Anyone else using 2.5mg on demand and getting results?

Of course, you can!

Although most would look at sildenafil as the on-demand pde5i believe it or not when taking tadalafil blood levels will reach the Tmax 0.8-1.2 hrs after you take it.

Top it off that the effects can last for 36 hrs.

Daily is the way to go and you will notice stronger/firmer/longer-lasting erections when erect and the penis will be fuller/plumper when flaccid let alone sensitivity/orgasms will increase due to improved blood flow and top it off that you will notice an increase in the quality of erections achieved during sleep NPT (nocturnal penile tumescence).

When you wake up in the middle of the night during NPT you will know what I mean.

Ones underlying vascular health will play a strong role in how well you respond to a said dose.

2.5-5 mg is the dose used when taking daily.

Many are using 5 mg/day but others may experience the beneficial effects when using a dose on the lower end of 2.5 mg/day.















 

Sergel

Member
Of course, you can!

Although most would look at sildenafil as the on-demand pde5i believe it or not when taking tadalafil blood levels will reach the Tmax 0.8-1.2 hrs after you take it.

Top it off that the effects can last for 36 hrs.

Daily is the way to go and you will notice stronger/firmer/longer-lasting erections when erect and the penis will be fuller/plumper when flaccid let alone sensitivity/orgasms will increase due to improved blood flow and top it off that you will notice an increase in the quality of erections achieved during sleep NPT (nocturnal penile tumescence).

When you wake up in the middle of the night during NPT you will know what I mean.

Ones underlying vascular health will play a strong role in how well you respond to a said dose.

2.5-5 mg is the dose used when taking daily.

Many are using 5 mg/day but others may experience the beneficial effects when using a dose on the lower end of 2.5 mg/day.















Wow that is a lot of info, thanks...

I did not take any yesterday but will try again tonight... although I feel achy this morning... legs back... Hmm... side effects? Will try again to see if the achyness returns or worsens... I read that for some the sides go away with use eventually...

This is a very powerful drug... I had no idea...
 

tropicaldaze1950

Active Member
Always glad to hear when something works for us older guys. Makes me sad, too. Even the tiniest dose(less than 2 mg) of tadalifil gives me gastro discomfort, mild headache and significant nasal congestion. I've tried the liquid version from BSP. Same sides. My wife, the few times she has been in the mood, thinks I should just get an erection the way I did, years ago. She has no interest in understanding male physiology.
 

LakeGuy81

Member
2.5-5 mg is the dose used when taking daily.

Many are using 5 mg/day but others may experience the beneficial effects when using a dose on the lower end of 2.5 mg/day.
Defy has me taking 1/4 of a 25MG pill (6.25mg) daily, I wonder if this is too much? But I'm also currently off TRT, so maybe they boosted it up to help me out. I do l think it's helping, as I'm able to have decent sexual encounters and orgasms even with low T in the 200-300 range. Defy prescribed it as kind of a "hold me over" until I get back on TRT, if I do. Lastly, is everyone taking the ODT's (Oral Disintegrating Tablets) or a normal pill you swallow?
 

Sergel

Member
Always glad to hear when something works for us older guys. Makes me sad, too. Even the tiniest dose(less than 2 mg) of tadalifil gives me gastro discomfort, mild headache and significant nasal congestion. I've tried the liquid version from BSP. Same sides. My wife, the few times she has been in the mood, thinks I should just get an erection the way I did, years ago. She has no interest in understanding male physiology.
So sorry it does not work for you... My girl is so sweet, never complained always played the hand she had... I have a great life companion... So imagine the giggles we have with this new renewed stiffy... I take it after lunch and no gastro issues... I take the original Lilly version if that makes a difference.
 

Sergel

Member
Defy has me taking 1/4 of a 25MG pill (6.25mg) daily, I wonder if this is too much? But I'm also currently off TRT, so maybe they boosted it up to help me out. I do l think it's helping, as I'm able to have decent sexual encounters and orgasms even with low T in the 200-300 range. Defy prescribed it as kind of a "hold me over" until I get back on TRT, if I do. Lastly, is everyone taking the ODT's (Oral Disintegrating Tablets) or a normal pill you swallow?
My short research found that many guys will work well with small doses, like 2.5 or 5mg... so I guess you would still be considered in the small doses... I mean a full dose is like 10 or 20 or 25 in your case...

I could not imagine being off TRT ... hope you can go back on soon...

I take the original Lilly Cialis, so regular swallow pills. My doc gave me 5mg that I cut in two..
 

Sergel

Member
Glad to confirm that just 2.5mg works wonders for me on demand... Darn... This is a very powerful drug... I am just amazed... Little context maybe. I am in good physical shape, good cardiovascular health, no health condition to speak of my only other medication is TRT ... So I guess that probably plays a role in why such a small dose works... It just gives me the little boost I need to perform better...
Anyhow, hope this thread helps someone...

I am so grateful for this forum...
 

Willyt

Well-Known Member
A belated thank you to @Sergel.
Over the last several years, I would sporadically use PDE-5 inhibitor at game time and got popped by the usual side effects every time (stuffy nose, wicked headaches, hangovers, backaches, etc.). I gave low dose daily Cialis/Tadalafil a shot at 2.5mg per day, but still had same side effects.

About 2 months ago, I decided to give daily Cialis one more shot after re-reading this thread. However, this time I tried microdosing at 0.62mg per day (1/4 of 2.5mg pill). To my surprise, I started reaping the benefits without the usual Cialis hangover. Eventually I got tired of trying to quarter the pills so I moved to 1.25mg (1/2 pill) every other day (EOD) with very similar results (despite the supposed 36 hour duration of Cilalis). I try to take each dose sublingually for better absorption although this is not always easy with such a small split pill.

This 1.25mg EOD dose is laughably low for many of you. The caveat is that I am sensitive to most medications. But the results have been promising so far (jinx). While microdosing does not provide the same intense experience as a normal dose, the effect has been consistently noticeable and without the nasty sides (as of yet).

The post-script is that I am starting to also appreciate the ancillary non-sexual benefits that many attribute to daily Cialis, some of which may be placebo effect. That topic goes beyond scope of this thread, but its something to explore (along with the potential downsides of long-term use)!
 
Last edited:

TXLongHorn55

New Member
A belated thank you to @Sergel.
Over the last several years, I would sporadically use PDE-5 inhibitor at game time and got popped by the usual side effects every time (stuffy nose, wicked headaches, hangovers, backaches, etc.). I gave low dose daily Cialis/Tadalafil a shot at 2.5mg per day, but still had same side effects.

About 2 months ago, I decided to give daily Cialis one more shot after re-reading this thread. However, this time I tried microdosing at 0.62mg per day (1/4 of 2.5mg pill). To my surprise, I started reaping the benefits without the usual Cialis hangover. Eventually I got tired of trying to quarter the pills so I moved to 1.25mg (1/2 pill) every other day (EOD) with very similar results (despite the supposed 36 hour duration of Cilalis).

This 1.25mg EOD dose is laughably low for many of you. I am admittedly sensitive to most medications. But the results have been promising so far (jinx). While microdosing does not provide the same intense experience as a normal dose, the effect has been consistently noticeable and without the nasty sides as of yet.

The post-script is that I am starting to also appreciate the ancillary non-sexual benefits that many attribute to daily Cialis. That topic goes beyond scope of this thread, but its something to explore (along with the potential downsides of long-term use)!
Can you comment on the manufacture of the 2.5 mg tadalafil you are usin?. Some pills are round and some are oval. The oval ones are impossible to cut in 1/4. Trying to locate a manufacturer that has 2.5 mg in the round shape. Thanks.
 

Willyt

Well-Known Member
Can you comment on the manufacture of the 2.5 mg tadalafil you are usin?. Some pills are round and some are oval. The oval ones are impossible to cut in 1/4. Trying to locate a manufacturer that has 2.5 mg in the round shape. Thanks.
The oval ones. You highlighted exactly why I moved from .62mg Daily to 1.25mg EOD - I couldn't quarter the oval pill with any precision. As I mentioned above, the results subjectively feel more or less the same.

One thing to note is that I originally had Empower 25mg pills which are very difficult to break down to a microdose with any degree of accuracy. I had to order the 2.5mg Tadalafil from my regular doctor. I cannot tell who the manufacturer is, but Walgreens fills the prescription if that helps.
 

TXLongHorn55

New Member
The oval ones. You highlighted exactly why I moved from .62mg Daily to 1.25mg EOD - I couldn't quarter the oval pill with any precision. As I mentioned above, the results subjectively feel more or less the same.

One thing to note is that I originally had Empower 25mg pills which are very difficult to break down to a microdose with any degree of accuracy. I had to order the 2.5mg Tadalafil from my regular doctor. I cannot tell who the manufacturer is, but Walgreens fills the prescription if that helps.
Thanks for the response. In the 5 mg option Walgreens has dispensed the round ones as well as the oval ones. Have been on the search for the round ones in the 2.5 mg option. It looks like Costco may have the round 2.5 mg option. Will follow up once confirmed.
 

TXLongHorn55

New Member
Thanks for the response. In the 5 mg option Walgreens has dispensed the round ones as well as the oval ones. Have been on the search for the round ones in the 2.5 mg option. It looks like Costco may have the round 2.5 mg option. Will follow up once confirmed.
Following up - can confirm that the 2.5 mg pills from Costco are round which make splitting easier. The pills are from NorthStar.
 

TXLongHorn55

New Member
The oval ones. You highlighted exactly why I moved from .62mg Daily to 1.25mg EOD - I couldn't quarter the oval pill with any precision. As I mentioned above, the results subjectively feel more or less the same.

One thing to note is that I originally had Empower 25mg pills which are very difficult to break down to a microdose with any degree of accuracy. I had to order the 2.5mg Tadalafil from my regular doctor. I cannot tell who the manufacturer is, but Walgreens fills the prescription if that

the 2.5 mg pills from Costco are round which make splitting easier. The pills are from NorthStar.
The oval ones. You highlighted exactly why I moved from .62mg Daily to 1.25mg EOD - I couldn't quarter the oval pill with any precision. As I mentioned above, the results subjectively feel more or less the same.

One thing to note is that I originally had Empower 25mg pills which are very difficult to break down to a microdose with any degree of accuracy. I had to order the 2.5mg Tadalafil from my regular doctor. I cannot tell who the manufacturer is, but Walgreens fills the prescription if that helps.
FYI - the 2.5 mg pills from Costco are round which make splitting easier. The pills are from NorthStar.
 

Willyt

Well-Known Member
FYI - the 2.5 mg pills from Costco are round which make splitting easier. The pills are from NorthStar.
What dose have you been taking daily? What are your observations so far?

I was doing well on microdose of 1.25mg EOD for number of weeks, but then started experiencing some acid reflux which I rarely get normally.
 
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