enclomiphene

  1. madman

    Enclomiphene Explained: Is It Better Than TRT?

    19:11 Why Enclomiphene Is So Unpredictable * the response is widely variable! Enclomiphene has quietly become one of the most prescribed men's health medications in America. It's marketed as the perfect alternative to testosterone replacement therapy (TRT): an oral medication that increases...
  2. madman

    Enclomiphene vs Clomiphene for Low Testosterone: Do They Work the Same for Boosting Testosterone, LH, and FSH?

    Abstract INTRODUCTION AND OBJECTIVES: Clomiphene citrate has been used off-label to treat male hypogonadism by stimulating endogenous gonadotropin secretion. Enclomiphene, the trans-isomer of clomiphene, is increasingly prescribed, but comparative data remain limited. We aimed to assess whether...
  3. E

    HCG + Enclomiphene - Helping, but need an added boost

    41 Years old I was on TRT for 8+ years without additional HCG or sperm production support. I tapered off last July and it wasn't near as bad as I thought it was going to be. The good news - I've been seeing a fertility specialist while following the following protocal: HCG- 3000iu's , 3X a...
  4. madman

    BSSM: Position Statement for the Potential Use of Enclomiphene in the Treatment of Male Hypogonadism

    * Enclomiphene is one of two stereoisomers of clomiphene, the other being Zuclomiphene. Whilst zuclomiphene is more oestrogenic, enclomiphene is more anti-oestrogenic. Zuclomiphene is generally antigonadotropic due to its effects on oestrogen receptors, which leads to a subsequent reduction in...
  5. madman

    Enclomiphene vs TRT: Where Does It Really Fit in Today’s HRT Landscape?

    Mohit Khera's personal experience with enclomiphene HPTA Conclusion
  6. M

    Advice on PCT Protocol After 3 Years on TRT?

    Hi everyone, I’m looking for advice on the best way to structure my PCT after being on TRT for about 3 years, specifically whether enclomiphene should overlap with HCG or only after HCG is discontinued. Here’s my full background and current plan: TRT History On TRT for ~3 years total Started...
  7. R

    Can enclomiphene or tamoxifen have favorable effects on intratesticular testosterone

    Background to question: There are primarily 2 indications for using medication to increase LH stimulation of the testes during TRT: 1. Preservation of spermatogenesis (Fertility) 2. Preservation of intrinsic testicular production of testosterone (and estradiol) (avoidance of testicular...
  8. D

    Switched from TRT to Enclomiphene...surprising results

    So I was on TRT recently for the last 2.5 years and decided to do a re-start and try Enclomiphene. I have been on & off TRT about 4x over past 15 years so and I did clomid when not on TRT...rather no get into all that though as it's a complicated story. So after 6 weeks of doing Enclomiphene...
  9. O

    Trouble Finishing (GLP-1 & TRT protocol discussion)

    Newly joined member here but have been lurking for 6mo learning and absorbing as much as I can here. Appreciate what an incredible resource this site is and the members contributing. I fell into the trap of eating poorly, drinking often, and spiraling my weight out of control in the last few...
  10. M

    DHEA and Pregnenolone best times to take

    I am taking 25 mg of DHEA and 5 mg of pregnenolone. My DHEA levels have lowered over time and my latest labs showed it was significantly low and decided I wanted to give it a try. I am on enclomiphene 12.5 EOD. I was taking DHEA and Pregnenolone after dinner and the other night I had a panick...
  11. D

    Enclomiphene price from Empower Pharmacy?

    Does anyone know what the price per pill for 25mg Enclomiphene is from Empower when ordering direct with a script?
  12. madman

    The Testosterone Revolution: Affordable Oral TRT, Enclomiphene, and Personalized Low T Care

    * Starting today, providers will be able to prescribe tailored doses of compounded enclomiphene4 through the Hims & Hers platform and, for men experiencing sexual symptoms, offer personalized testosterone care that combines enclomiphene with tadalafil in a single dual-action treatment. *...
  13. M

    From enclomiphene to TRT cream - where do I stand?

    Hey all, I’ve been on topical TRT compounded cream (100 mg/day) for 52d now. No prior exogenous T before this. 50mg twice daily (AM/PM), rotating between behind knees, deltoids, and inner thighs. Chose to avoid transscrotal application as I didn't want to spike DHT/E2. I was on enclomiphene at...
  14. Nelson Vergel

    Can Clomiphene / Enclomiphene Reverse Testicular Atrophy? Review of Limited Data.

    Below is a synthesis of what the literature presently shows about clomiphene (and its trans-isomer enclomiphene) and reversal of testicular atrophy in men. What hard data exist? Setting Study design (n) Testicular-volume result Time to observation Secondary hypogonadism, enclomiphene 25...
  15. T

    High E2 (~50 pg/mL) on HCG/Enclomiphene/Anastrozole: Mood, Acne, Fog

    I'm 38, on a fertility protocol/hormone optimization (HCG 250 IU 2x/week, Enclomiphene 12.5 mg daily, Anastrozole) for 80 days. Latest blood work (May 16th 2025): T level at 1376 ng/dL, E2 at 50-55 pg/mL. Doc said E2 was high, so they increased Anastrozole to 0.25 mg 2x/week ~2 weeks ago...
  16. J

    Enclomiphene on TRT for Fertility

    I think I saw a video a while back with @Nelson Vergel saying some men use Enclomiphene while on TRT and some inexplicably become fertile using that method. What are the cons of trying that? If I wanted to throw that Hail Mary, what dose of Enclomiphene should I use?
  17. M

    Enclomiphene dosages

    I am 4 weeks into enclomiphene, I made the switch from clomid after being on it for 2 years. Currently I am taking 12.5 mg ed. I am not getting labs until june. Curious on dosages, I hear EOD,every third day. So far no side effects that I know of. Thinking I stay on course until june before...
  18. RotnGun

    My blood test results on enclomiphene

    Okay, so 8 weeks ago I stopped taking my daily test cyp and HCG. For two weeks prior, I slowly tapered off the test cyp and HCG until I was injecting 3mg of test cyp and 30iu of HCG per day. After 4 days of being totally off the test cyp and HCG, I started to take 5mg of enclomiphene per day...
  19. M

    Long Term Clomid use experience

    Hello everyone, I am posting this simply to share my experience and would love for anyone to share theirs. I have been on clomid for almost 2.5 years now straight. I take 100 mg a week so 50 mg every 3 days. I have used 0 anabolics and I am 27 years old. My numbers have been fantastic. 1200...
  20. DixieWrecked

    Enclomiphene and it's uses

    Alright guys, was doing some thinking. People take serms to recover from TRT or their steroid cycles. I was thinking that this would actually be almost pointless. SERMS block the the hypothalamus' estrogen receptor which we all know stimulates the release of GnRH. But if you are shutdown...
  21. Nelson Vergel

    Compounded Hormone Products for Men: A Review by Shaun Noorian

    In this conversation, Nelson Vergel and Shaun Noorian discuss the various options available for men's hormonal treatments, focusing on hormone replacement therapy, the role of compounding pharmacies, and the importance of personalized medicine. They explore specific medications such as DHEA...
  22. M

    Maximus Native T: Gel vs Oral

    Hoping Dr. Cam can chime in here. 65 y/o male. 1st phase of my recomp via a cut accomplished. Was finally able to drop 30lbs and bodyfat from 26% to sub 10% with no loss in muscle mass. Will be lean bulking with the goal to add 20lbs of LBM w/o adding bf via lean bulk Enclomiphene update...
  23. K

    Higher heart rate on enclomiphene

    Anyone else have this experience? I'm taking 24mg/week for 2 months now.
  24. Nelson Vergel

    Enclomiphene versus clomiphene study results

    Among 66 patients, enclomiphene exhibited a median testosterone increase of 166 (vs. 98 ng/dL, P=0.20) with lower estradiol change than clomiphene (–5.92 vs. 17.50 pg/mL, P=0.001). Adverse effects were statistically significantly less frequent with enclomiphene, including decreased libido...
  25. T

    Enclomiphene advice 35 yr old man

    Ok so background first. I'm 35 was 34 when I lab tested found to find my test was very low about 300.(will attach some labs) sorry they are all out of order if you will look at collection dates. Now I've had test come back kinda all over threw the years some time low some time low/average but...
  26. T

    Can Enclomiphene replace HCG in PCT?

    My body does not tolerate HCG well at all. Nipples get sensitive, I bloat like a pufferfish, and overall just feel terrible. I used to be on TRT and blast and cruise for about 10 years, then came off all of it altogether. I did no PCT, just quit cold turkey and my levels returned to normal...
  27. B

    Enclomiphene dose

    I had at one point taken clomid 50mg 3x a week to resutls in 1000ng total test and above reference range free test. I had to stop due to eye floaters. Now i bought some enclomiphene and wonder what dose I should start with. Technically if clomid is a 50/50 isomer, then 25mg 3x a week would be...
  28. G

    Is depression along tiredness normal for a clomid restart after Trt? Almost 6 weeks in i believe. Really hoping for another baby

    questions in bold below for those who want to skip... Reddit is of no use and ive read through some stuff here but any encouragement or advice would be huge. Me and my wife just turned 37 and im sad we waited so long to try for our second. On trt for 3 and a half years and hcg didnt work. On a...
  29. madman

    Maximus: Oral TRT+ (native T + enclomiphene + pregnenolone)

    Today we’re excited to announce a breakthrough in men’s hormone optimization: Maximus' Oral TRT+ Protocol. Testosterone, without injections or messy creams, all while maintaining fertility markers. Timestamps: 0:00 - 0:09 - Introduction 0:10 - 3:54 - What is Maximus Oral TRT+? 3:55 - 4:44 -...
  30. B

    Doctors in San Diego

    I had a great setup, a ND that was working under an MD that did billing to my insurance co. The company dissolved and everyone went cash pay. I have Blue Shield PPO and have been getting extensive labs and TRT covered for over 3 years. Just need to find a doc that bills insurance. I hear that...
  31. G

    Enclomiphene restart - how long?

    38M who has been on TRT + HCG for ~5 years or so. I wanted to see if I could restart production with the help of enclomiphene, as prior to TRT I had a great response to clomid but could not handle the estrogen related sides. I started 12.5mg ED about a month ago, and just got back labs from a...

enclomiphene

enclomiphene

Members online

Beyond Testosterone Podcast

Back
Top