Testosterone

Oral Testosterone Therapy: A Complete Guide to Jatenzo, Tlando, Kyzatrex, and Emerging Options
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Oral Testosterone Therapy: A Complete Guide to Jatenzo, Tlando, Kyzatrex, and Emerging Options By Nelson Vergel | ExcelMale.com | Updated December 2025 For decades, men requiring testosterone replacement therapy faced a limited menu of options...
Sexual Function on TRT: Why Testosterone Alone May Not Be Enough for Erectile Function
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Many men begin testosterone replacement therapy expecting their sexual function to improve across the board—better libido, stronger erections, enhanced satisfaction. And while TRT often delivers significant benefits for desire and overall sexual...
Fewer than half of HIV+ men found to have low testosterone are treated with TRT
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This nationwide study examines the prevalence of testosterone deficiency and the subsequent use of replacement therapy among men living with HIV. By analyzing data from over 100 million patients, researchers discovered that healthcare providers...

US Federal and State Regulations on Testosterone and HCG

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Testosterone is a controlled substance in the US, specifically a Schedule-III controlled substance (in all but one State), and this includes any form of testosterone including injectable, transdermal, patches, pellets, and any compound or product...
Key Historical Failures and Lessons Learned from Attempts to Get a Testosterone Product FDA-Approved for Women
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FDA Approval of Testosterone Therapy for Women: An Analysis of Historical Failures, Regulatory Hurdles, and a Path Forward Executive Summary The landscape of testosterone therapy presents a stark gender disparity: while over 31 FDA-approved...
HCG Use in Men on TRT or as Monotherapy: Over 200 Questions and Answers
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I collected questions and answers posted on ExcelMale.com in the last 10 years about the use of human chorionic gonadotropin in men who want to prevent loss of testicular size and fertility while on testosterone replacement therapy or that want...
Upcoming FDA Expert Panel on Testosterone Replacement Therapy for Men
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@Nelson Vergel We need you here! https://www.fda.gov/patients/fda-expert-panels/fda-expert-panel-testosterone-replacement-therapy-men-12102025 Location: FDA White Oak Campus, 10903 New Hampshire Ave., Building 31, Great Room, Silver...
Practical Clinical Summary on Testosterone Therapy in Women
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Practical Clinical Summary on Testosterone Therapy in Women (From ExcelMale.com) Based on the ExcelMale forum threads and related clinical literature, here's a comprehensive extraction of practical content for a clinical article: Physiological...
FDA Removes Black Box Warning: What the New HRT Guidelines Mean for Women’s Health and HRT
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Dr. Rachel Rubin and Dr. Kelly Caspersen discuss with FDA Commissioner Dr. Marty Makary the significant impact of hormone replacement therapy (HRT) on women's health, particularly in the context of recent FDA changes to black box warnings. They...
How to Find a Good Doctor that Prescribes Testosterone Plus hCG: TRT Near Me
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Looking for a qualified TRT doctor who prescribes testosterone and HCG? Finding the right physician can make or break your hormone optimization journey. Many doctors are poorly trained in testosterone replacement therapy—they under-dose, skip...
Dr. Shalender Bhasin: Optimizing the Diagnosis and Treatment of Hypogonadism 2025
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Nelson's house u heard it here first! Dr. Shalender Bhasin! * over the past 4 decades he has become a global leader in the biology of androgens, sarcopenia and aging related functional decline, his research has shaped clinical guidelines, its...
Best HCG Dose for Men on TRT: Two Studies That Used HCG with Testosterone
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What's the optimal HCG dose to preserve fertility and testicular size while on testosterone replacement therapy? Two landmark studies provide critical guidance for men seeking to maintain reproductive function during TRT. Research from Baylor...
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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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