Testosterone

Why Use hCG With TRT?- A Clinical Review
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Using hCG in Men on Testosterone Replacement Therapy (TRT) – A Clinical Review Introduction Exogenous testosterone replacement therapy (TRT) can profoundly suppress the hypothalamic-pituitary-gonadal (HPG) axis through negative feedback. By...
The Evolution of Testosterone Products in the U.S. (1935-2025)
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Thanks to Dr Sun for this diagram. Timeline details (left → right) YearProduct (image above/below the line)Form & delivery 1935-1937No product image—text block below the line: “Testosterone first synthesized” with a bullet list of early...
Shifting the Testosterone Treatment Paradigm with Oral Testosterone (Kyzatrex)
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Again you heard it here first! Nelson's domain the one and only! Very informative webinar on the use of the newer oral TU formulations. Testosterone therapy has long been dominated by injectable and topical formulations, but the landscape...
Testosterone Replacement Therapy (TRT) Facts Every Man Should Know
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Testosterone Replacement Therapy (TRT) can be life-changing for many men suffering with low testosterone symptoms. However, there are crucial facts that most men are not told by their physicians before they start TRT. Here are the top facts that...
Smoking Cessation's Effects on Male Hormonal Levels
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This scientific paper investigates the effects of smoking cessation on hormonal levels in men, specifically focusing on steroid hormones like testosterone, DHEA, DHEAS, cortisol, and sex hormone-binding globulin (SHBG). The researchers aimed to...
The hormonal regulation of men’s sexual desire, arousal, and penile erection
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Briefing Document: Hormonal Regulation of Male Sexual Desire, Arousal, and Penile Erection Source Rastrelli, G., Antonio, L., Carrier, S., Isidori, A., & Maggi, M. (2025). The hormonal regulation of men’s sexual desire, arousal, and penile...
Erectile Dysfunction Therapies: Testosterone, PD-5 Inhibitors, & Beyond
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Can we do more than prescribe pills to address men’s sexual health complaints? In this episode of the BackTable Urology Podcast, men’s health expert Dr. Mohit Khera from Baylor College of Medicine joins guest host Dr. Amy Pearlman for a deep dive...
Best HCG Dose for Men on TRT: Two Studies That Used HCG with Testosterone
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Note:HCG mimics LH but it is not LH and it's not picked up by the LH blood test. In fact, it suppresses LH like endogeneous testosterone does. But the amazing thing that the study below found is that HCG can increase sperm production and quality...
Where to get Testosterone prescriptions?
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Been on TRT for almost two years. It's been life changing. I take .9 to 1cc per week of Enanthate injected. Took a while to dial it in, but 800 to 1000 seems to be the sweet spot for me. Then primary care physician retired, new guy want's it to...
Eating More Live Microbes May Boost Testosterone: What a New Study Found
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A new study published in Scientific Reports (Nature Publishing Group) has found a potential link between eating foods rich in live microbes—like those found in yogurt, kefir, kimchi, and other fermented foods—and higher testosterone levels in...
Where to Inject Testosterone: Intramuscular vs. Subcutaneous Injections
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No matter what kind of TRT your doctor has given you, a common question is where to inject testosterone. For decades, most men have injected their testosterone intramuscularly (IM), primarily into the glutes, quadriceps, or deltoids, using a 1 to...
Testosterone blood level is correlated with immune cell abundance in transgender young people on gender affirming hormones
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Sex hormones like estrogen and testosterone don’t just affect things like body shape or voice—they also play a role in how the immune system works. This is especially important for transgender people who take these hormones as part of their...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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