High Hematocrit

Iron Supplementation Protocol to Raise Ferritin FAST While on TRT: The Vorck Protocol
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The Vorck Protocol Summary Background: The protocol was developed by a TRT user since 2001 who had difficulty recovering ferritin levels after blood donations. After conducting personal research and consulting with a hematologist in May 2021, he...
Elevated Hematocrit from Testosterone Therapy vs High-Altitude Adaptation: A Comparative Analysis
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From this thread: WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT - Excel Male TRT Forum Underlying Physiological Mechanisms Testosterone Replacement Therapy (TRT) and Erythrocytosis: Exogenous...
WARNING: Do not believe Internet "gurus" proclaiming no need to manage hematocrit on TRT
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Debunking the Myth About High Hematocrit in Men on TRT I know many of you want to feel reassured that managing hematocrit isn’t necessary. However, misinformation is spreading, with some "bro science" videos and even a few so-called expert...
Testosterone Therapy Induced High Hematocrit- Can Therapeutic Phlebotomy Be a Double-Edged Sword?
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https://ec.bioscientifica.com/view/journals/ec/aop/ec-24-0283/ec-24-0283.xml Therapeutic Phlebotomy: A Double-Edged Sword? Current Guidelines: "Several endocrine organizations mention therapeutic phlebotomy as a means of treating TTh–induced...
New Drug Rusfertide: Managing Polycythemia Vera to Reduce Risks and Improve Lives
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Polycythemia vera is a classic myeloproliferative neoplasm and a chronic type of leukemia, which often leads to overproduction of various blood cells. Summary: Managing Polycythemia Vera to Reduce Risks and Improve Lives Polycythemia vera (PV)...
Controversies with Testosterone Replacement Therapy: Lecture by Dr Khera
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As usual Nelson's Excel is where it's at! Mohit Khera, MD, MBA, MPH, Professor of Urology, F Brantley Scott Chair in Urology, Medical Director of the Laboratory for Andrology Research, Medical Director for the Scott Department of Urology...
Rises in Hematocrit is Associated with An Increased Risk of Cardiac Events in Men Starting Testosterone Therapy
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ABSTRACT Objective Elevated hematocrit (Hct) can result in increased risk of major adverse cardiac events(MACE) in men receiving testosterone therapy (TTh). However, the impact of the magnitude of the change in Hct from baseline after starting...
High hematocrit in men receiving testosterone therapy (Pellets, Nasal, and Injections)
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Prevalence of secondary erythrocytosis in men receiving testosterone therapy: A matched cohort analysis of intranasal gel, injections, and pellets (2023) Rohit Reddy*, Parris Diaz*, Ruben Blachman-Braun, Justin Loloi, Farah Rahman, Jesse Ory...
Management of Erythrocytosis in Men Receiving TRT
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Management of Erythrocytosis in Men Receiving Testosterone Therapy: Clinical Consultation Guide (2022) Pranjal Agrawal, Sajya M. Singh, Taylor Kohn 1. Introduction Testosterone deficiency, previously known as male hypogonadism, affects...

Minimizing Erythrocytosis during TRT (Daily injectable Testosterone vs. Gels vs. Kyzatrex)

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All, I react very badly to injectable T (56 hematocrit @ 100 mg split 3x per week SubQ). My ferritin suffers greatly here and sits in the 20's to low 30's. I want it to be above 70. Testosterone have given me a severe case of periodic limb...
Beyond Testosterone: The Illustrated Guide is Now on Amazon
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"Beyond Testosterone" is a comprehensive 427-page guide authored by Nelson Vergel, a seasoned expert in the realm of hormone therapy. With a vibrant full-color layout and extensive illustrations, this book stands as an essential resource for both...
Oral Testosterone Kyzatrex Did not Affect Semen Parameters & Hematocrit in Hypogonadal Men: Pilot Study
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Hot off the press! * No significant changes in semen parameters or other reproductive hormones were observed after 3 months of treatment. Larger scale studies are needed to fully evaluate the effects of oral testosterone formulations on semen...
TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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