Erectile Dysfunction

Pregnenolone in Men: Help determining proper dosage and frequency

Jun 21

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Hi all, I've been experimenting with pregnenolone for over a year now, with varied success. I seem to get benefits at 100mg (such as higher libido, more pronounced nighttime erections and better sleep); however, I don't get these results...

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The hormonal regulation of men’s sexual desire, arousal, and penile erection

Jun 21

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Briefing Document: Hormonal Regulation of Male Sexual Desire, Arousal, and Penile Erection Source Rastrelli, G., Antonio, L., Carrier, S., Isidori, A., & Maggi, M. (2025). The hormonal regulation of men’s sexual desire, arousal, and penile...

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Erection Supplements- Do They Work to Improve ED?

Jun 18

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Briefing: Erection Supplements and Erectile Dysfunction (ED) This briefing reviews information from the "Erection Supplements- Do They Work to Improve ED?" discussion on the Excel Male TRT Forum, focusing on the efficacy, safety, and regulatory...

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Erectile Dysfunction Therapies: Testosterone, PD-5 Inhibitors, & Beyond

Jun 17

Can we do more than prescribe pills to address men’s sexual health complaints? In this episode of the BackTable Urology Podcast, men’s health expert Dr. Mohit Khera from Baylor College of Medicine joins guest host Dr. Amy Pearlman for a deep dive...

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Best HCG Dose for Men on TRT: Two Studies That Used HCG with Testosterone

Jun 15

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Note:HCG mimics LH but it is not LH and it's not picked up by the LH blood test. In fact, it suppresses LH like endogeneous testosterone does. But the amazing thing that the study below found is that HCG can increase sperm production and quality...

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Why Men’s Fertility Is Declining: The Truth About Testosterone

Jun 13

In an insightful interview from the "Dr. Gabrielle Lyon" YouTube channel, Dr. Larry Lipshultz, a renowned expert in male reproductive health, discusses the alarming global decline in male fertility, attributing it to factors such as obesity...

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High Estradiol in Men on TRT: What to Do

Jun 11

Briefing Document: Estradiol in Men on TRT Source: Excerpts from "High Estradiol in Men on TRT: What to Do" by Nelson Viegel (excelmale.com) 1. The Role and Importance of Estradiol in Men Core Idea: Estradiol, often misconstrued as a solely...

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Research Advances in Stem Cell Therapy for ED

May 30

Stem Cell Therapy for Erectile Dysfunction: Current Evidence and Future Directions Erectile dysfunction (ED) is a prevalent condition affecting men worldwide, particularly those between the ages of 40 and 70. While conventional treatments such...

Erectile Dysfunction Men's Health

Managing the Testosterone-to-Estradiol Ratio in Men on TRT

May 29

Managing the Testosterone-to-Estradiol Ratio in Men on TRT Introduction Testosterone replacement therapy (TRT) in hypogonadal men often leads to an increase in estradiol (E2) levels due to the aromatization of testosterone. This alters the...

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The TRT Guide from ExcelMale.com

May 17

Understanding the Symptoms, Diagnosis, and Treatment of Hypogonadism in Men Hypogonadism, a condition characterized by low testosterone levels, can significantly impact a man's quality of life. ExcelMale.com offers a comprehensive guide to help...

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What Every Man Needs to Know | Testosterone 101

May 17

Testosterone is a key hormone for men's health, but what happens when levels drop? In this episode, Dr. Alex Tatem and KG break down everything you need to know about testosterone—what it is, signs of deficiency, when to get tested, and the best...

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Overcoming Premature Ejaculation

May 06

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In this episode, we discuss premature ejaculation, a problem faced by 30-40% of men at some point in their lives. *But what defines premature ejaculation and, for that matter, what is considered a normal time to ejaculation? *10 minutes? 5...

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TRT Hormone Predictor Widget

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038