Why do i need to keep increasing my t4 and t3 dose? Endogenous production?

Robotics

Active Member
it seems like after a dose increase i get my levels balanced (t4,t3) but then slowly my levels fall again. I am guessing that it is because endogenous production reduces due to a negative feedback loop similar to that of testosterone?

Does my endogenous production have to be completely shutdown to reach a balance? (TSH 0?) or can i find and stay at a balance of say tsh 1? because with testosterone, if endogenous production is still going that means that the exogenous dose is likely not high enough. can someone explain this system to me?
 

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