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  1. Gianluca

    If endogenous thyroid peaks at night/early am, why do we take exogenous during the day?

    According to this study, Thyroid level are at the highest between 10pm and 10am, why then everyone takes it during the day? wouldn't make sense to take the first dose at night before bed, and second right after waking up? I may want to try this actually. Free Triiodothyronine Has a Distinct...
  2. K

    Blood test results - TRT and Hypothyroidism

    Recently I have done my blood work and my doctor told me that everything is ok... However, after doing my own research on thyroid hormones, low t, prolactin etc I know that there is something wrong with my body. Now I know that I might have subclinical hypothyroidism and that may be the cause...
  3. K

    Blood Work Help

    Recently I have done my blood work and my doctor told me that everything is ok... However, after doing my own research on thyroid hormones, low t, prolactin etc I know that there is something wrong with my body. Now I know that I might have subclinical hypothyroidism and that may be the cause...
  4. K

    Blood Work - Please Help

    Recently I have done my blood work and my doctor told me that everything is ok... However, after doing my own research on thyroid hormones, low t, prolactin etc I know that there is something wrong with my body. Now I know that I might have subclinical hypothyroidism and that may be the cause...
  5. W

    Men on NDT, what dose are you taking?

    Hi guys, I’m curious how much NDT you are taking. I’m sure it varies somewhat per individual but nonetheless I’m trying to get a “ball-park” estimate. Please mention the brand of NDT too. Thanks.
  6. S

    Armour thyroid dose

    Is it possible to take take much armour thyroid? At four grains daily my levels are still low.
  7. W

    Do I have T3 pooling?

    I have been taking 2 grains (120mg) of NDT and recently got lab work done. The STTM (Stop the Thyroid Madness) community said I have T3 pooling going on because my Free T4 is low while Free T3 is high, indicating higher Reverse T3 not allowing the Free T3 to enter into the cells. Hence, the...
  8. S

    DHEA supplementation for hypothyroidism DHEA supplementation may exert a beneficial effect on thyroid autoimmunity and hypothalamic-pituitary-thyroid axis activity in men with autoimmune thyroiditis and subclinical hypothyroidism.
  9. A

    Excessive sweating on thyroid medications

    Hi guys. I've been doing well so far with the introduction of thyroid medications to my regimen. It seems TRT alone was slowly killing my already lazy thyroid and I was feeling always tired and in a low mood state, despite proper androgens numbers on paper. I then started adding T4 first, but...
  10. M

    Low cortisol

    I have been on trt for many years, last few years just not feeling well, thought it was my trt dose or estrogen, ran many blood tests and found out recently my cortisol has been consistently low, went to the Hospital and they ran the Cortrosyn stimulation test on me and my adrenals did not...
  11. T

    is thyroid meds similar to TRT ?

    hello, with TRT, you take a smidge of testosterone, your own production goes awol completely, it's like an all or nothing effect. is taking thyroid meds like this? thinking of starting it up and making my life even more complicated since the shitshow that trt produces clearly isnt enough for me...
  12. T

    Weird reaction to Levothyroxine and reverse T3 issues

    I was diagnosed with sub clinical hypothyroidism around 6 months ago, I was very much symptomatic despite only having a TSH of 3ish and low but in range T3 and T4 levels. I was initially put on NDT (NP thyroid but that did little to change any of my symptoms, doctor put me on Levothyroxine...
  13. B

    B12, thyroid, and best calcium supplement

    How's it going everyone? I have 2 concerns. I want to double check my knowledge. My first understanding is that vitamin b12 does not interfere with thyroid testing - only biotin does. Is this true or should all b vitamins be avoided to have accurate thyroid testing? Secondly, I currently have...
  14. B

    Supplementing T4 with thyroid Labs

    Hey guys. I got my thyroid numbers today. In my country we get levothyroxine without prescription in pharmacies. I am thinking about supplementing T4 to bring my TSH between 1-2. What dose should I start with. 25 mg or better 50. Since starting TRT my TSH is climbing continuously. TSH: 2.23...
  15. W

    Optimal Thyroid Numbers

    I been looking around trying to find what optimal thyroid numbers are. Not having any luck, everything just gives what's considered in range. Which is a pretty wide gap. Has anyone seen in info on this before?
  16. A

    Question about dosage of T3/T4 dosing and Thyroid values.

    63 years of age and have struggled with fat loss for decades. I walk 70,000+ steps per week, lift weights 5 days per week. I eat a very strict diet consisting of: oatmeal, chicken breast, salmon, lean pork, vegetables, yogurt. I weight the meat for correct portion control. I am...
  17. K

    How does Thyroid hormone effect Estrogen and Aromatase?

    I have searched for the answer endlessly and only got conflicting reports . Does Thyroid hormone ( T4,t3) reduce Estrogen or raise it ? What is their effects on the aromatase enzyme ? Thank you . All seems very confusing and I think the TRT/testosterone community could benefit from the correct...
  18. M

    Thyroid or T - Problems?

    Hi, not sure where to go. Symptoms: low energy, fatigue are my biggest. followed by no libido, cold hand & feets + brainfog. labs show following: TSH - 0.79 ( Ref 0.3 - 3.18) fT3 - 4.65 (Ref 4.09 - 6.65) fT4 - 16.8 ( Ref 13.1 - 21.3) Testosteron 3.86 ( Ref 2.49 - 8.36 ) SHBG 23.5...
  19. T

    Pregnancy disrupts the accuracy of automated fT4 immunoassays Are we having fun yet?
  20. I

    Thyroid Blood Work Experiment: Do Beef Thyroid Supplements do something?

    For a long time, I've seen many experts say TSH should be around 1-2 or 1-1.5. In my blood work, my TSH is always higher and I have a tendency to gain fat easily. Before messing with meds, I decided to try Beef Thyroid supplements a shot, to try to see if this could make any difference to get...
  21. Gianluca

    My labs on 2 grains Armour, looking for feedback on FT4

    I was surprised to see these results, as based on Stop The Thyroid Madness, I really thought optimal would be achieved with over two grains. I wasn’t able to hold the dose for a full month before labs due to traveling, but actually a bit less than 4 weeks. My GF also on the same dose, but held...
  22. Gianluca

    Thyroid/Adrenal Optimization slides by Dr John Crisler

    Dr Crisler (RIP) slides on thyroid health.
  23. T

    Low libido - subclinical hypothyroidism? Iodine deficiency?

    Hello, is it possible have low libido and poor erection due to low iodine? And I also have symptoms as hypothyroidism (hair loss, dry skin, cold intolerance, poor memory and concentration)? My blood results: TSH varies from 3.7 to 1.98 (0.350 - 4.94) Ant TG: <15 (0 - 115) FT4: 12.45 (9.01 -...
  24. M

    Anyone using T2 as a fat burner?

    A few doctors have touted the little-known thyroid hormone T2 to be used to help burn brown fat. Since there is only a tiny amount (8mg) in my NDT, I was thinking of adding it for the purported benefits...
  25. USMC

    My Recent Thyroid Blood Test Results

    Glad they appear to be normal: TESTS FLAG UNITS RESULTS PREVIOUS RESULTS Thyroid Stimulating Hormone Normal uIU/mL 3.770 NORMAL Ref Range: 0.270-4.200 uIU/mL NOTES: N/A Triiodothyronine, Free (FT3) Normal pg/mL 3.34 NORMAL Ref Range: 2.50-4.30 pg/mL NOTES: N/A...
  26. Gianluca

    The hypoglycemic side of hypothyroidism

    Hypoglycemia is a not so infrequent condition encountered in endocrine practice. Considered an inevitable (though modifiable) part of diabetes therapy, hypoglycemia occurs fairly often, in both type 1 and type 2 diabetes, in patients on oral hypoglycemic agents and insulin, and in indoor as well...
  27. Gianluca

    Thyroid Hormone Promotes Insulin-induced Glucose Uptake by Enhancing Akt Phosphorylation and VAMP2 Translocation in 3T3-L1 Adipocytes

    Abstract The purpose of this study was to test a hypothesis that T3 promotes glucose uptake via enhancing insulin-induced Akt phosphorylation and VAMP2 translocation in 3T3-L1 adipocytes. T3 significantly enhanced insulin-induced phosphorylation of Akt, cytoplasma to cell membrane translocations...
  28. S

    Swollen Thyroid

    Hi everyone I'm 46 and i've been suffering from decreased sex drive since I turned 40("Life begins at 40 eh?") before that I always considered myself to have a very healthy sex drive. Three months ago I was travelling and decided to get one of all these comprehensive medical checks, it was...
  29. G

    Testosterone causing hypo symptoms

    Fellas, often do you inject? Has it had a impact on your thyroid? I started in April of 2020, and last year around October I started having problems, and now I can connect them to TRT. It seems it somehow Impacting my thyroid function. I just went up to 112 mcg, and I dont have a problem with T3...
  30. D


    I've been popping half a gram of l-tyrosine with my t4 each morning, temperature rises much faster. Reading 98.x most mornings by 7:30. Any drawbacks to this?
  31. D

    T4 helps me sleep. Anyone else?

    Most nights I wake after a good nap. Last night about 2:30 woke right up. Maybe most people wake but return to sleep quickly perhaps. I was up until 4ish. Theanine wasn't enough to go back down. I decided to take T4(50ug) at that time. Takes about an hour I guess but woke sleeping like a baby...
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