Does Iron do more with thyroid than help convert T4 to T3?

Anonymon

Active Member
I read someone in another thread mention that without enough iron, T3 can’t get into the cell. I’m familiar with the usual things you’d read on Thyroid and iron levels, and am wondering if anybody would know if it was involved in more than just helping convert T3 to T4 in an abstract way, and allowing for high enough cortisol to make the dance work. Any insights would be helpful.
 
Iron is needed for myogoblin which is similar to hemoglobin, but myogoblin is found in muscle tissue and provides muscles with oxygen.

Myogoblin binds oxygen more tightly than hemoglobin.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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