Nelson Vergel
Founder, ExcelMale.com
TRT Resources Hub
Your Complete Guide to Testosterone Replacement Therapy
Your Complete Guide to Testosterone Replacement Therapy
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Welcome to ExcelMale's TRT Resources Hub!
This thread consolidates our best educational content into one easy-to-navigate guide. Whether you're just starting to research TRT or you're optimizing an existing protocol, you'll find organized, evidence-based information here.
How to use this guide:
• Scroll to find your topic of interest
• Click any link to open the detailed discussion thread
• Bookmark this page for quick reference
• Reply below with suggestions for additions
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QUICK NAVIGATIONNew to TRT? • Injections • Creams & Gels • Oral TRT
Lab Testing •
Side Effects • Hormones • Videos • Special Topics───────────────────────────────────────────────────
SECTION 1: New to TRT? Start Here
Essential reading for anyone considering or just starting testosterone therapy.
What is a Normal Testosterone Level?
Understanding lab ranges, reference values, and what clinical guidelines recommend
Potential Causes of Low Testosterone
Medical conditions, lifestyle factors, medications, and diagnostic considerations
Pre-TRT Checklist
Everything to complete before starting therapy - labs, baseline measurements, questions
Top Facts Before Starting TRT
Critical information every man should understand about testosterone therapy
What to Expect When Starting TRT
Timeline of effects, realistic expectations, and common early experiences
How Long Does TRT Take to Work?
Week-by-week breakdown of when different benefits typically appear
How Low is Too Low?
Health consequences of untreated low testosterone
Learn Quickly About T Deficiency
Featured comprehensive overview for beginners
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SECTION 2: Injectable Testosterone
The most common and cost-effective TRT delivery method.
Overview & Products
Testosterone Products Guide (110K+ views)
Complete overview of all available testosterone formulations
Evolution of T Products (1935-2025)
Historical development of testosterone therapies
Carrier Oils Analysis
Cottonseed, grape seed, sesame - formulations and clinical implications
Injection Techniques
Where to Inject: IM vs SubQ
Comparison of injection sites and methods
SubQ Injections Complete Guide
Comprehensive 2025 guide to subcutaneous technique
IM vs SubQ: Clinical Comparison
Effects on TT, hematocrit, E2, and PSA
Shallow IM Injections
Technique for reduced pain and better absorption
SubQ Injection Studies
Research supporting subcutaneous administration
Dosing & Protocols
SteroidPlotter Guide
Understanding dosing, ester weights, and blood level curves
Why 200mg/Week Upper Limit? (220K+ views)
Dosing rationale explained
Dose Response Study
Effects of different doses on body composition, strength
Heavier Men May Need Higher Doses
Body weight considerations in dosing
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SECTION 3: Topical Testosterone (Creams & Gels)
Improving Gel Absorption (59K views)
Tips for maximizing topical testosterone effectiveness
Atrevis Hydrogel Cream (Empower)
Experience reports and results with new formulation
Scrotal Testosterone Cream
Benefits for libido and DHT conversion
Successful Cream Protocol
Member experience with optimization
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SECTION 4: Oral Testosterone
New oral options approved since 2019.
Oral TRT Complete Guide
Jatenzo, Tlando, Kyzatrex, and emerging options
Oral TRT Products Comparison
Side-by-side analysis including DITEST native T
Kyzatrex Updates
Latest news and experiences with Kyzatrex
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SECTION 5: Other Delivery Methods
Pellets, Sublingual & Buccal
Alternative delivery methods explained
Nasal Testosterone (Natesto)
Pre-workout experiment and results
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SECTION 6: Lab Testing & Monitoring
TRT Monitoring Lab Tests
What to test, when to test, interpreting results
Top 10 Monitoring Tips
Expert guidance on tracking your progress
Monthly Testosterone Variations
Study results on natural fluctuations
Order Lab Tests (DiscountedLabs)
Affordable blood testing without a doctor visit
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SECTION 7: Side Effects & ManagementTRT Side Effects: Prevention & Reversal
Comprehensive guide to common issues and solutions
Testosterone Drug Interactions
Medications that affect testosterone or are affected by it
Alcohol and Testosterone
Impact on blood levels and therapy effectiveness
Tolerance to TRT?
Myth vs reality on long-term effectiveness
Getting Off TRT: HPTA Recovery
Protocol for discontinuing testosterone therapy
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SECTION 8: Understanding Your Hormones
SHBG (Sex Hormone Binding Globulin)
SHBG: Complete Guide for TRT
Comprehensive 2025 guide to understanding SHBG
What is the Purpose of SHBG?
Function, importance, and role in hormone balance
SHBG Function Explained
Detailed discussion of SHBG mechanics
How to Increase Low SHBG (109K views)
Strategies and interventions
Other Hormones & Sexual Health
Factors in Libido & Erections
Beyond testosterone - all the variables that matter
HCG and Libido
Studies and prescription guidance
TRT and Clomid Together
Combination therapy discussion
TRT + GLP-1 Medications
Combining with semaglutide, tirzepatide
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SECTION 9: Video Resources
TRT Products Video Review
Nelson Vergel's comprehensive overview
Testosterone Controversies & Myths
Lecture by Dr. Mohit Khera
Hypogonadism Lecture
In-depth educational presentation
Hypogonadism 101
Video series for beginners
All ExcelMale TRT Videos
Complete video library
ExcelMale YouTube Channel
Subscribe for new content
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SECTION 10: Books & Guides
TRT Clinical Guide (Free)
ExcelMale's comprehensive downloadable guide
Beyond Testosterone (427 pages)
Nelson Vergel's illustrated comprehensive guide
Testosterone: A Man's Guide
Available in 197 countries
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SECTION 11: Special Topics
Travel & Legal
Traveling with T and HCG (38K views)
Domestic travel guide
International Travel with TRT
Country-specific considerations
U.S. State Laws
State-by-state legal considerations
Insurance Coverage Issues
Navigating denials and appeals
Special Populations
TRT for Elderly (80+)
Special considerations for older men
TRT in Trans Men
Hormone replacement considerations
Natural Approaches & Weight
Boost Testosterone Naturally (47K views)
Non-TRT interventions
Testosterone and Weight Loss
Evidence for T's effect on body composition
Testosterone Dose for Muscle (61K views)
Dosing considerations for hypertrophy
Other Topics
TRT and Immune System
Effects of testosterone on immunity
Declining T Levels in Population
Evidence of generational testosterone decline
Questions for Your TRT Doctor
What to ask at your appointment
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SECTION 12: Tools & Resources
Testosterone Tools Website
Comprehensive calculator and tool suite
TRT Hormone Predictor Widget (see sidebar)
Estimate E2, DHT, Free T from Total T
HCG Mixing Calculator (see sidebar)
Protocol calculator for HCG reconstitution
Where to Find Supplies
Affordable syringes, labs, ED drugs, HCG, Trimix
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QUICK REFERENCE LINKS
Find a TRT Doctor • Order Lab Tests • YouTube Channel
Nelson's Books • Join Forum •
About ExcelMale
Find a TRT Doctor • Order Lab Tests • YouTube Channel
Nelson's Books • Join Forum •
About ExcelMale───────────────────────────────────────────────────
About This Hub
Last Updated: January 2026
Maintained by: @Nelson Vergel and the ExcelMale team
Have a suggestion? Reply below with threads that should be added to this hub. We update this resource regularly to ensure it reflects the best information available.
Looking for something specific? Use the forum search function or ask in a new thread - our community is here to help!
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This hub consolidates content from dozens of individual threads. All original threads remain accessible for detailed discussion.
