TRT doubts 8 weeks in

[M!ck]

Hi guys,

I am 8 weeks into trt, enanthat 40mg e3.5d subQ.

Started low, as I was having a history 6 years ago with trt and elevated hematocrit.

My results came in and I was shocked. HCT already came back at 52.2 and total T at 11.8ng/ml which was surprisingly high as well for that low dose. Bloods were taken around 68 hours after last injection.

The reason that I have started trt at all was tanked energy, brainfog, loss of libido.
When I went to the gym I felt tanked after. No stress in my life, diet clean. Bf around 16% with 81kg. I hoped for more energy, but yet after 8 weeks it’s not that much better honestly. A little bit maybe.

My total T in the last 5 years had been around 3.8 and shbg low around 23. So there was still some production ongoing.

Not sure if it was a goood call for me to start honestly and if I’m doing More harm than good.

Love to hear your ideas to my situation. I am hesitate to stop and recover my own production at the moment.
Thanks.

 

[Cataceous]

In spite of popular belief, 80 mg of testosterone enanthate per week is not a low dose. It's providing more testosterone than most men would ever make naturally. Your lab results are not surprising. It sounds like your pre-TRT Vermeulen calculated free testosterone was around 9 ng/mL. This is considered borderline, low enough to cause problems for some men. In view of your symptoms it wasn't unreasonable to trial TRT. I would have preferred to see it done initially with a less disruptive fast-acting form, such as testosterone nasal gel or buccal troches. But given where you are, it would be sensible to lower your dose and give it some more time. Going to 60 mg TE per week is reasonable with your numbers, but it would be better with three injections per week, or every-other-day if you could manage that.

If you still don't see improvements in another eight weeks then you may need to rethink this. I assume you've had lab testing to rule out other potential reasons for your symptoms—thyroid issues, etc.? Because TRT suppresses and disrupts other hormones, men often get better results by adding hCG to the protocol. However, I haven't seen many guys referencing improvements in energy and cognition with this.

Unfortunately TRT is not a panacea, and it is possible that your original testosterone level was not low for you as an individual. You will find opinions contrary to mine, with encouragement to try even higher doses. If you are tempted then at least try the lower-dose route first. You should experience levels that are likely closer to what was healthy and natural for you before you increase your risk with higher doses—higher HCT at a minimum.

 

[M!ck]

In spite of popular belief, 80 mg of testosterone enanthate per week is not a low dose. It's providing more testosterone than most men would ever make naturally. Your lab results are not surprising. It sounds like your pre-TRT Vermeulen calculated free testosterone was around 9 ng/mL. This is considered borderline, low enough to cause problems for some men. In view of your symptoms it wasn't unreasonable to trial TRT. I would have preferred to see it done initially with a less disruptive fast-acting form, such as testosterone nasal gel or buccal troches. But given where you are, it would be sensible to lower your dose and give it some more time. Going to 60 mg TE per week is reasonable with your numbers, but it would be better with three injections per week, or every-other-day if you could manage that.

If you still don't see improvements in another eight weeks then you may need to rethink this. I assume you've had lab testing to rule out other potential reasons for your symptoms—thyroid issues, etc.? Because TRT suppresses and disrupts other hormones, men often get better results by adding hCG to the protocol. However, I haven't seen many guys referencing improvements in energy and cognition with this.

Unfortunately TRT is not a panacea, and it is possible that your original testosterone level was not low for you as an individual. You will find opinions contrary to mine, with encouragement to try even higher doses. If you are tempted then at least try the lower-dose route first. You should experience levels that are likely closer to what was healthy and natural for you before you increase your risk with higher doses—higher HCT at a minimum.

Thanks for your reply, really appreciate it.
Yeah my testosterone levels 16 years ago were likely the same than 8 weeks ago, so I didn’t see a massive drop. 7 years ago it went down to 200 but I was likely overtraining and carrying more bodyfat with me.

My free t were likely what you calculated. I did some measurements for it as well. They came back mostly around 8.x. Even during the afternoon. I did full bloodwork’s like a lot, tested for everything I could think of. Also vitamins. My thyroid, my testicles, my heart got ultrasounded, everything is fine. Have seen different Endos, Uros. They all say I’m in range I don’t need therapy, my problems are elsewhere. Did 2 sleep studies, negative for apnea. What I could think of is that my nose is not that straight and I might have kind of UARS which messes up with my sleep cycles. My sleep is fine, I measure it religiously with a tracker, sometimes my deep sleep and REM is lowish but other than that I always score 80-95 points.

I’m living in Germany so my hormone treatment is limited and no nastesto or troches is available. I only have my pcp on hand who is willing to treat my symptoms and he has no clue of it but gives me what I need.

I’ll attach a bloodwork for you, so you could take a look at some values if you would like to. It’s not the newest one, I have seen an internist who did a comprehensive scan for my thyroid, my t3 came back much higher than that.

Currently I don’t really feel a big difference between a total T of 3.8 or 11.x to be honest. Maybe even worse, my heart is giving out some extra systoles, might be due to elevated hematocrit, was having it couple of month ago as well.

As I don’t feel any better after 8 weeks I strongly think about to jump off again and trt to optimize again wherever I could. I don’t know.

I

 

[madman]

Hi guys,

I am 8 weeks into trt, enanthat 40mg e3.5d subQ.

Started low, as I was having a history 6 years ago with trt and elevated hematocrit.

My results came in and I was shocked. HCT already came back at 52.2 and total T at 11.8ng/ml which was surprisingly high as well for that low dose. Bloods were taken around 68 hours after last injection.

The reason that I have started trt at all was tanked energy, brainfog, loss of libido.
When I went to the gym I felt tanked after. No stress in my life, diet clean. Bf around 16% with 81kg. I hoped for more energy, but yet after 8 weeks it’s not that much better honestly. A little bit maybe.

My total T in the last 5 years had been around 3.8 and shbg low around 23. So there was still some production ongoing.

Not sure if it was a goood call for me to start honestly and if I’m doing More harm than good.

Love to hear your ideas to my situation. I am hesitate to stop and recover my own production at the moment.
Thanks.

I am 8 weeks into trt, enanthat 40mg e3.5d subQ.

Started low, as I was having a history 6 years ago with trt and elevated hematocrit.

My results came in and I was shocked. HCT already came back at 52.2 and total T at 11.8ng/ml which was surprisingly high as well for that low dose. Bloods were taken around 68 hours after last injection.


You are hitting a very high TT 1180 ng/dL 68 hrs post-injection and seeing as you are injecting twice-weekly this is not your true trough (lowest point) before your next injection which would be 84 hrs post-injection so your true trough TT would still be high but lower than 1180 ng/dL.

Again although TT is important to know FT is what truly matters as it is the unbound active fraction of T responsible for the positive effects.

You are missing one of the most critical markers here.

You stated that you have always had somewhat lowish SHBG low 20s but on your most recent blood work you never even had it tested to see where it truly sits.

Was it driven lower?

If it is still 23 nmol/L then with a very high TT 1180 ng/dL it is a given that your FT would be high as in cFTV 35.1 ng/dL.

Keep in mind your peal TT and more importantly FT would be higher.

Even then without knowing where your SHBG truly sits with a very high TT 1180 ng/L 68 hrs post-injection so 16 hrs shy of your true trough even if you were one who had high SHBG 60 nnmol/L your cFTV 20.3 ng/dL would still be high-end!

Yes you would easily have room to lower your dose further and bring down your trough FT if need be.

As you can see from your thread 2021 that I posted below you already tried a lower weekly dose 50-60 mg T split twice-weekly and you were hitting a robust trough TT 595 ng/dL which would have had you hitting a healthy trough cFTV 15.6 ng/dL if your SHBG was 23 nmol/L.

Keep in mind your peak TT and more importantly FT would be higher.

You felt. good for 1.5 years other then your elevated hematocrit.

Seems to be an ongoing issue here.

M

Thread 'Expertise on my TRT needed'

Apr 11, 2021

Hi everybody,

I’m from Germany and struggling to find a good doc in my region, that’s why I’m looking for help online.

To my person, I’m 40, doing bodybuilding since 20 years, no cycle ever.
With age 30 I had my test checked and have been at the lowest end, but still in range. Since a couple of years my body composition changed to more belly fat and the main thing is, I am tired af and have no energy.

So I went to my doc who is not an expert and got my test measured again, it was 2,01 , so below range (2.49 - 8.36 μg/l)

another test 2 years ago showed 2,93. So I went to see my...

• M!ck
• trt
• Replies: 46
• Forum: Testosterone Basics & Questions

• 

i was still thinking that I need that damn trt and started with it with my home doc. I injected e3.5d about 50-60mg. No hcg, no ai. I felt good for 1.5 years, had energy, could feel my muscles again, my body comp changed, all good. Test on trough 5,95 (maybe too high)

But now my hematocrit was creeping up to .53 and I was having constant headaches and was short of breath. So I wanted to give blood which was denied of high hemoglobin. My doc and I did a phlebotomy 4 weeks ago where I collapsed. i developed a bad sleep apnea which made me gasping for air during the night.That all made wanted to stop injecting stuff and I stopped. After a week I started 20mg Ed tamoxifen to start my hpta again, but now 2 weeks later it’s hard for me to find energy for something, when my wife and I are on the couch I fall asleep at 9pm, think my restart is not kicking. My balls do not really grow.

Yesterday I was in a so damn mood that I injected 40mg test and immediately I felt better.
that was a mistake I guess. Next week I will see my doc to check where’s my hematocrit is at. And I have absolutely no idea about how to continue.

 

[M!ck]

I am 8 weeks into trt, enanthat 40mg e3.5d subQ.

Started low, as I was having a history 6 years ago with trt and elevated hematocrit.

My results came in and I was shocked. HCT already came back at 52.2 and total T at 11.8ng/ml which was surprisingly high as well for that low dose. Bloods were taken around 68 hours after last injection.


You are hitting a very high TT 1180 ng/dL 68 hrs post-injection and seeing as you are injecting twice-weekly this is not your true trough (lowest point) before your next injection which would be 84 hrs post-injection so your true trough TT would still be high but lower than 1180 ng/dL.

Again although TT is important to know FT is what truly matters as it is the unbound active fraction of T responsible for the positive effects.

You are missing one of the most critical markers here.

You stated that you have always had somewhat lowish SHBG low 20s but on your most recent blood work you never even had it tested to see where it truly sits.

Was it driven lower?

If it is still 23 nmol/L then with a very high TT 1180 ng/dL it is a given that your FT would be high as in cFTV 35.1 ng/dL.

Keep in mind your peal TT and more importantly FT would be higher.

Even then without knowing where your SHBG truly sits with a very high TT 1180 ng/L 68 hrs post-injection so 16 hrs shy of your true trough even if you were one who had high SHBG 60 nnmol/L your cFTV 20.3 ng/dL would still be high-end!

Yes you would easily have room to lower your dose further and bring down your trough FT if need be.

As you can see from your thread 2021 that I posted below you already tried a lower weekly dose 50-60 mg T split twice-weekly and you were hitting a robust trough TT 595 ng/dL which would have had you hitting a healthy trough cFTV 15.6 ng/dL if your SHBG was 23 nmol/L.

Keep in mind your peak TT and more importantly FT would be higher.

You felt. good for 1.5 years other then your elevated hematocrit.

Seems to be an ongoing issue here.

M

Thread 'Expertise on my TRT needed'

Apr 11, 2021

Hi everybody,

I’m from Germany and struggling to find a good doc in my region, that’s why I’m looking for help online.

To my person, I’m 40, doing bodybuilding since 20 years, no cycle ever.
With age 30 I had my test checked and have been at the lowest end, but still in range. Since a couple of years my body composition changed to more belly fat and the main thing is, I am tired af and have no energy.

So I went to my doc who is not an expert and got my test measured again, it was 2,01 , so below range (2.49 - 8.36 μg/l)

another test 2 years ago showed 2,93. So I went to see my...

• M!ck
• trt
• Replies: 46
• Forum: Testosterone Basics & Questions

• 

i was still thinking that I need that damn trt and started with it with my home doc. I injected e3.5d about 50-60mg. No hcg, no ai. I felt good for 1.5 years, had energy, could feel my muscles again, my body comp changed, all good. Test on trough 5,95 (maybe too high)

But now my hematocrit was creeping up to .53 and I was having constant headaches and was short of breath. So I wanted to give blood which was denied of high hemoglobin. My doc and I did a phlebotomy 4 weeks ago where I collapsed. i developed a bad sleep apnea which made me gasping for air during the night.That all made wanted to stop injecting stuff and I stopped. After a week I started 20mg Ed tamoxifen to start my hpta again, but now 2 weeks later it’s hard for me to find energy for something, when my wife and I are on the couch I fall asleep at 9pm, think my restart is not kicking. My balls do not really grow.

Yesterday I was in a so damn mood that I injected 40mg test and immediately I felt better.
that was a mistake I guess. Next week I will see my doc to check where’s my hematocrit is at. And I have absolutely no idea about how to continue.

Hi madman,

Thanks for joining in. You are right, it’s an ongoing issue and I am spinning my wheels back and forth.

My SHBG is in my bloods above it was 23.5.
But yeah in my actual bloods i didnt get it measured, that was my fault.

To make things clear, 6 years ago my weekly dose was 100mg with my trough at 5.9.
So that’s why I started even lower than that this time with 80mg only (week)

What drives me nuts this time is that I don’t feel a big difference 8 weeks later after starting, no high libido, no more energy, still sleepy.. so this gives me right now a feeling that something else might be my problem and that I spent all the years thinking that testosterone must be my missing piece.

BUT your quote of my old post is interesting that I felt good for 1.5 years. And that’s true, I still remember my good feeling.
So here I am again. Lost.

 

[madman]

Hi madman,

Thanks for joining in. You are right, it’s an ongoing issue and I am spinning my wheels back and forth.

My SHBG is in my bloods above it was 23.5.
But yeah in my actual bloods i didnt get it measured, that was my fault.

To make things clear, 6 years ago my weekly dose was 100mg with my trough at 5.9.
So that’s why I started even lower than that this time with 80mg only (week)

What drives me nuts this time is that I don’t feel a big difference 8 weeks later after starting, no high libido, no more energy, still sleepy.. so this gives me right now a feeling that something else might be my problem and that I spent all the years thinking that testosterone must be my missing piece.

BUT your quote of my old post is interesting that I felt good for 1.5 years. And that’s true, I still remember my good feeling.
So here I am again. Lost.

Okay my mistake as I was thinkiing 50-60 mg/week split but it was 50-60 mg every 3.5 days (100-120 mg/week) which still had you hitting a robust trough TT 595 ng/dL and more importantly you would have been hitting healthy trough cFTV 15.6 ng/dL if your SHBG was hovering in the low 20s nmol/L.

On your current protocol 68 hrs post-injection so 16 hrs shy of your true trough you would be hitting a very high cFTV 35.1 ng/dL and keep in mind peak FT will be higher.

Your body is amped up on T 24/7 which can easily backfire for some men especially when it comes to libido mind you this is 8 weeks in but even then you should be feeling better and seeing some improvements overall.

Downfall here is libido is multifactorial.

Yes having healthy T levels are critical when it comes to libido but it is only one piece of the puzzle as there is much more involved here.

As I have stated in previous threads over the years I would put much more weight behind sleep, diet, exercise, thyroid/adrenals and stress (physical/mental) when it comes to energy, mood, libido, erectile function and overall health than supposedly needing a high/absurdly high FT.

Have you every though about giving any of the newer oral TU formulations (Jatenzo, Tlando or Kyzatrex) a go as it would be a better option than running high/very high trough/steady-state FT levels 24/7 on injections if you are struggling with elevated hematocrit.

Much shorter lived peaks and more time spent at trough as the peaks are fairly short-lived and levels will come down quicker in close to/back to baseline 8-12 hrs post-dose which can minimize driving up the hematocrit.

Would be a great option to seek out but unfortunately you live in Germany and would not have access
yet.

As of now you would only have access to the older granddaddy oral TU formulation Andriol which is not commonly used anymore due to low bioavailability and the uncertain absorption as the formulation is heavily reliant on dietary fat intake to help increase absorption but unfortunately this resulted in significant intra- and inter-patient variability in testosterone response.

 

[M!ck]

As I have stated in previous threads over the years I would put much more weight behind sleep, diet, exercise, thyroid/adrenals and stress (physical/mental) when it comes to energy, mood, libido, erectile function and overall health than supposedly needing a high/absurdly high FT.

I think that’s the most important one for me, I bought a nasal dilator couple of weeks ago and my deep and rem sleep got a lot of better. Maybe my sleep/breathing was the root cause for my fatigue all the time.

I have decided to try it again without trt, my last shot is 8 days ago and since 3 days I’m feeling fantastic. So it seems my mind can’t handle elevated T levels currently. Don’t know where I’m sitting right now, but I hope I will recover quickly and see how it goes with my better sleep. Maybe I’ll get my nose fixed by surgery and when it still doesn’t help at all I can jump back in trt.

And yeah, you’re right, in Germany there is no other great option available for treatment. Usually there is only Gel or Nebido. So bad. Hope it will come in the future.

 

[madman]

I think that’s the most important one for me, I bought a nasal dilator couple of weeks ago and my deep and rem sleep got a lot of better. Maybe my sleep/breathing was the root cause for my fatigue all the time.

I have decided to try it again without trt, my last shot is 8 days ago and since 3 days I’m feeling fantastic. So it seems my mind can’t handle elevated T levels currently. Don’t know where I’m sitting right now, but I hope I will recover quickly and see how it goes with my better sleep. Maybe I’ll get my nose fixed by surgery and when it still doesn’t help at all I can jump back in trt.

And yeah, you’re right, in Germany there is no other great option available for treatment. Usually there is only Gel or Nebido. So bad. Hope it will come in the future.

You should bounce back quick but keep in mind you will always go back to baseline or in some cases when men have been on therapy or abused T/AAS for years natty levels can end up lower than baseline and recovery can be long especially for fertility.

Retest in 3 months to see where your true baseline sits and make sure you go in the early AM within a few hours after awakening in a fasted state otherwise your results will be skewed.

Always use the most accurate assays TT/estradiol (LC-MS/MS) and FT (Equilibrium Dialysis) and throw in SHBG too.

 

[FunkOdyssey]

. HCT already came back at 52.2 and total T at 11.8ng/ml which was surprisingly high as well for that low dose

What was your baseline pre-TRT HCT? I feel like guys who are this high on their first follow-up labs are usually dealing with pre-TRT problems (sleep apnea, insulin resistance, diabetes, smokers, obesity) that are being exaggerated by a bit of added testosterone. This should not be happening in an otherwise healthy male.

 

[M!ck]

You should bounce back quick but keep in mind you will always go back to baseline or in some cases when men have been on therapy or abused T/AAS for years natty levels can end up lower than baseline and recovery can be long especially for fertility.

Retest in 3 months to see where your true baseline sits and make sure you go in the early AM within a few hours after awakening in a fasted state otherwise your results will be skewed.

Always use the most accurate assays TT/estradiol (LC-MS/MS) and FT (Equilibrium Dialysis) and throw in SHBG too.

I will do so, thanks for your help madman.

Decided to not take a Serm as it was only 8 weeks on a small dose, think too that I should recover quickly. My last shot is already 11 days ago and I still feel good, having some mitochondria support like l-carnitin and q10. let’s see by the end of the week when 2 weeks are over, but I’m positive.
Fenugreek and cistanche are in the mail to give me a little extra boost

 

[M!ck]

What was your baseline pre-TRT HCT? I feel like guys who are this high on their first follow-up labs are usually dealing with pre-TRT problems (sleep apnea, insulin resistance, diabetes, smokers, obesity) that are being exaggerated by a bit of added testosterone. This should not be happening in an otherwise healthy male.

46, and I have none of your listed problems. i did 2 sleep studies to rule this out before. But I still can imagine that I’m having kind of UARS as my nose was crooked and one side is not that open.

 

[FunkOdyssey]

I bought a nasal dilator couple of weeks ago and my deep and rem sleep got a lot of better. Maybe my sleep/breathing was the root cause for my fatigue all the time.

I still can imagine that I’m having kind of UARS as my nose was crooked and one side is not that open.

What you're describing (problems breathing during sleep to the point that sleep is disrupted) is essentially sleep apnea and will have similar adverse effects on health, whether you technically met the criteria for it in a sleep study or not.

This is likely the pre-existing condition that caused you to immediately respond to TRT with excessive hematocrit.

 

[dirkdigglr]

One thing I’ve noticed is that when I go to sleep, my nose often partly clogs up, almost like the tissue swells when I lie down. Then I sometimes end up breathing more through my mouth.

I tried a nasal spray for a while, and it helped open the nose, but it dried my nose out pretty badly, so I’m not sure that’s a good long-term solution. My Oura also sometimes shows small breathing disturbances — not a lot, but they do show up occasionally. Not sure if this is related.

Is this a concern for impaired sleep already?

 

[FunkOdyssey]

One thing I’ve noticed is that when I go to sleep, my nose often partly clogs up, almost like the tissue swells when I lie down. Then I sometimes end up breathing more through my mouth.

 

[M!ck]

One thing I’ve noticed is that when I go to sleep, my nose often partly clogs up, almost like the tissue swells when I lie down. Then I sometimes end up breathing more through my mouth.

I tried a nasal spray for a while, and it helped open the nose, but it dried my nose out pretty badly, so I’m not sure that’s a good long-term solution. My Oura also sometimes shows small breathing disturbances — not a lot, but they do show up occasionally. Not sure if this is related.

Is this a concern for impaired sleep already?

Having the same, would love to take nasal spray each evening but it’s no longterm solution.

 

[M!ck]

View attachment 57062

Helps kind of, but after couple of nights my skin reacts.
Switched to this one:

Noson Nasendilatator​

 

[M!ck]

What you're describing (problems breathing during sleep to the point that sleep is disrupted) is essentially sleep apnea and will have similar adverse effects on health, whether you technically met the criteria for it in a sleep study or not.

This is likely the pre-existing condition that caused you to immediately respond to TRT with excessive hematocrit.

The sleep studies came back with less than 1 event (breathing outage) per hour.
SPO2 always in the higher ranges like 97-99% during the night.
But on my tracker I’m seeing too short sleeping episodes, like interrupted rem and deep sleep. My above posted device definitely helps already. Maybe I should consider a nasal op.

 

[madman]

I will do so, thanks for your help madman.

Decided to not take a Serm as it was only 8 weeks on a small dose, think too that I should recover quickly. My last shot is already 11 days ago and I still feel good, having some mitochondria support like l-carnitin and q10. let’s see by the end of the week when 2 weeks are over, but I’m positive.
Fenugreek and cistanche are in the mail to give me a little extra boost

I would tread lightly when it comes to those T boosters!



post #2 (Go nuts!)

Thread '"T-Up: Understanding Testosterone Boosting Supplements"'

Oct 7, 2024

In this episode, hosts Dr. Kevin Chu and Dr. Justin Dubin delve into the world of testosterone-boosting supplements with expert Dr. Geo Espinosa. As patients frequently inquire about these well-known supplements, the conversation aims to clarify their efficacy and whether they can serve as an alternative to traditional testosterone therapy.

Dr. Geo Espinosa, a naturopathic and functional medicine doctor at NYU's Department of Urology, offers invaluable insights into prostate health, penile health, and male testosterone. As the CMO and formulator for...

• madman
• t-boosters; testosterone; benefits/risks
• Replies: 2
• Forum: Nutrition and Supplements

 

[M!ck]

I would tread lightly when it comes to those T boosters!



post #2 (Go nuts!)

Thread '"T-Up: Understanding Testosterone Boosting Supplements"'

Oct 7, 2024

In this episode, hosts Dr. Kevin Chu and Dr. Justin Dubin delve into the world of testosterone-boosting supplements with expert Dr. Geo Espinosa. As patients frequently inquire about these well-known supplements, the conversation aims to clarify their efficacy and whether they can serve as an alternative to traditional testosterone therapy.

Dr. Geo Espinosa, a naturopathic and functional medicine doctor at NYU's Department of Urology, offers invaluable insights into prostate health, penile health, and male testosterone. As the CMO and formulator for...

• madman
• t-boosters; testosterone; benefits/risks
• Replies: 2
• Forum: Nutrition and Supplements

Very interesting, thanks for that link man.
I’d think I will not throw them in when my booster arrive, ordered them cause I was in fear of a crash when my exogenous T is leaving. But still I’m feeling better than ever.

 

[Systemlord]

One thing I’ve noticed is that when I go to sleep, my nose often partly clogs up, almost like the tissue swells when I lie down. Then I sometimes end up breathing more through my mouth.

I tried a nasal spray for a while, and it helped open the nose, but it dried my nose out pretty badly, so I’m not sure that’s a good long-term solution. My Oura also sometimes shows small breathing disturbances — not a lot, but they do show up occasionally. Not sure if this is related.

Is this a concern for impaired sleep already?

I was iron deficient for 2 1/2 years and when I would lay down, I couldn’t breathe through my nose, it’s like my sinus cavities were swollen up because it wasn’t enough oxygen in my blood. Supplementation of iron got rid of it immediately. Strangely, this was also my original symptoms before I had low testosterone diagnosis and when I went on your TRT, it went away until I became iron efficient months later.