TRT beyond age 65

[Parajack]

I’m 65 and been on TRT for 15 years (30 mgs Tcyp E3D subQ no AI - never body building or lifting). I’ve gotten lazy about regular testing last several years other than watching hematocrit but have felt fine and have just been plugging along. Then I had a jaw joint go bad which really screwed up my neck and took me in to all kinds of issues - including Cervicogenic vertigo. I found a miracle surgeon to deal with the jaw and and am recovering well but still dealing with the low grade nausea and vertigo from all of the neck issues. I feel like shit much of the time and I need to determine if the TRT is any kind of player or if it’s unrelated.

My ask is other than getting blood work up to date, what’s the evolution of decision making for deciding if TRT still makes sense for me going forward? It’s not so much about libido and sexual drive anymore. I certainly enjoy the drive but not clear anymore on the risk/reward curve. Seems it’s just a giant “inconclusive” in terms of scientific study relating to cardiovascular health, etc. The hints I’ve been picking up on seem to suggest that maybe it’s time to stop or reconsider at 65+.

I’m getting organized as a new patient with Defy medical. Are they gonna be my best resource to help me decide if I should continue or not? What other resources should I be exploring to help me decide if it’s time to call it quits with TRT? Are the only good answers gonna come if I just stop for several months and see how I feel? Thanks for any replies.
Jack

 

[Nelson Vergel]

I am so sorry that you have gone through that jaw issue. Hopefully, you will recover and heal nicely. Vertigo is not fun!

I would stay on your TRT dose.

Defy Medical may bring in hCG and daily Cialis.

Any studies that show that HCG improves libido ? How do I get a HCG prescription?

Hi, I recently had an operation for a craniopharyngioma, a benign brain tumor. It was located near the pituitary gland so after the operation my pituitary gland was damaged so that it doesn't produce any hormones anymore. I now take all the hormones in pill-form, and use androgel to raise my...

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The benefits of long term use of Cialis

An oldie but goodie...still relevant today as it was then. Good shit! The Benefits of Long Term Cialis Use Cialis (tadalafil) is powerful.. What makes Cialis unique among the erectile dysfunction drugs is its long half life. Thirty six hours after taking Cialis, a guy will still have about a...

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Trimix is also a super potent option for older men (I am 63) who want to be super performers in bed.

Penis Injections for Hard Erections: TRIMIX

Trimix or Quadmix—Available by prescription from compounding pharmacies. These are mixtures of prostaglandins and papaverine that increase blood flow and retention into the penis. Prostaglandins are mediators and have a variety of strong physiological effects, such as regulating the contraction...

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You may want to watch this video to make you feel better about TRT use while you age:

 

[Lumalux]

Agreed with the Trimix. It works on pretty much everyone, every time, and would give a corpse a boner. If anything, the excitement of seeing yourself at full mast may be enough to get the ball rolling so to speak. I think once you experience it, your interest will return. Don't ever stop wanting to be horny.

 

[Systemlord]

My ask is other than getting blood work up to date, what’s the evolution of decision making for deciding if TRT still makes sense for me going forward?

Testosterone Level: How Low is Too Low? Health Consequences of Low Testosterone

I was able to summarize all available studies on testosterone blood levels and how they are linked to several health issues. I will add references soon. Low Blood Levels of Testosterone and Associated Risks: < 450 ng/dl (15.3 nmol/l) - Risk of metabolic syndrome Reference: Dhindsa, S...

www.excelmale.com

Testosterone Threshold for Increased Cardiovascular Risk in Middle-Aged and Elderly Men: A Locally Weighted Regression Analysis - PubMed

These data showed that a testosterone threshold of 440 ng/dL was associated with increased Framingham 10-year CVD risk in middle-aged and elderly men. Poor sexual performance, decreased morning erection, and loss of libido had an impact on the testosterone threshold for CVD risk. The threshold...

pubmed.ncbi.nlm.nih.gov

These data showed that a testosterone threshold of 440 ng/dL was associated with increased Framingham 10-year CVD risk in middle-aged and elderly men. Poor sexual performance, decreased morning erection, and loss of libido had an impact on the testosterone threshold for CVD risk. The threshold level was higher in men with sexual dysfunction.

Testosterone and the Heart - PMC

Testosterone (T) has a number of important effects on the cardiovascular system. In men, T levels begin to decrease after age 40, and this decrease has been associated with an increase in all-cause mortality and cardiovascular (CV) risk. Low T ...

www.ncbi.nlm.nih.gov

Testosterone (T) has a number of important effects on the cardiovascular system. In men, T levels begin to decrease after age 40, and this decrease has been associated with an increase in all-cause mortality and cardiovascular (CV) risk. Low T levels in men may increase their risk of developing coronary artery disease (CAD), metabolic syndrome, and type 2 diabetes. Reduced T levels in men with congestive heart failure (CHF) portends a poor prognosis and is associated with increased mortality. Studies have reported a reduced CV risk with higher endogenous T concentration, improvement of known CV risk factors with T therapy, and reduced mortality in T-deficient men who underwent T replacement therapy versus untreated men. Testosterone replacement therapy (TRT) has been shown to improve myocardial ischemia in men with CAD, improve exercise capacity in patients with CHF, and improve serum glucose levels, HbA1c, and insulin resistance in men with diabetes and prediabetes. There are no large long-term, placebo-controlled, randomized clinical trials to provide definitive conclusions about TRT and CV risk. However, there currently is no credible evidence that T therapy increases CV risk and substantial evidence that it does not. In fact, existing data suggests that T therapy may offer CV benefits to men.

My advice is stay on TRT.

 

[Guided_by_Voices]

What are "the hints you are picking up"? I have never heard of any compelling case where TRT is a net negative, but it has many positives. Many men are starting at your age. And if you want to maintain any quality of life, strength, (both muscle and bone), mobility, and balance are essential and that means lifting weights along with some other things which TRT is helpful for. It may also not be possible for you to restart enough of your own production to be healthy.

 

[Fred52]

I'm 55 now and starter TRT over 10 years ago. My plan is to never stop. If I live to 100 I will be injecting T.

 

[KevinS]

I started last year at 60, I wish I would have started at 50 - would have made a huge difference in the last 10 years. I feel 'myself' for the first time in many years. No winter blues, back to the gym, losing weight putting on muscle.

 

[FlowRW]

I started TRT at 66. Wish I had started at 46 (maybe 36). I go to the gym 4 to 5 days a week. Try to stay active although YouTube is going to be the death of me. Only "old" person in the neighborhood that does all their own yard work. I feel better now that I did 20 years ago. I see no reason to stop TRT.

 

[DragonBits]

LOL, I asked that very question.

In 2015, I saw Dr. Nieberberger about increasing my fertility, and also asked him what age his oldest client on testosterone was. He said one man just quit TRT at age 90.

Sounds reasonable, I am going to think about quitting at 90.

Craig Niederberger, MD is the Clarence C. Saelhof Professor and Head of the Department of Urology at the University of Illinois at Chicago; he also holds a joint appointment as Professor in the Department of Bioengineering in the College of Engineering at UIC.

BTW, I am 69, started when I was 57.