Trans scrotal testosterone cream application is a game changer

So I was on injections of Testosterone cyp for almost 4 years before switching over to scrotal testosterone cream application. Let me tell you it has been absolutely amazing how much better I feel on the cream verses the injections. I dose it at 150 mg daily (3 clicks), 50 mg in the morning before bed (I work nights) and 100 mg about an hour before I leave for work at night. I was doing daily sub q injections for the past couple years, 20 mg cyp daily. I felt good on that protocol, but this blows that protocol out of the water. I messed up and did labs about 2 hours after my application and everything came back out of range, with free t at 48. I would encourage anyone interested to give the scrotal t-cream application a go, I can't see myself ever going back to injections.

 

What Mechanism of trt would cause an increase in gerd? Just curious. Mine actually sleeks to have gotten better since being on trt.

I found a rat study that might shed some light on what's happening with people having gastritis or GERD on TRT:

Gastric secretion, proinflammatory cytokines and epidermal growth factor (EGF) in the delayed healing of lingual and gastric ulcerations by testosterone - PubMed

Hormonal fluctuations are known to predispose ulceration of the upper gastrointestinal tract, but to date no comparative study of their effects on the healing of pre-existing ulcers in the oral cavity and stomach has been made. We studied the effects of depletion of testosterone and of EGF on...

pubmed.ncbi.nlm.nih.gov

 

magnesium And vitamin c are my most consistent supplements. But even then I’m not religious with.

Have you ever taken creatine monohydrate?

 

Have you ever taken creatine monohydrate?

yes. Didn’t notice much

 

@Charliebizz quick question, do u experience any noticeable high DHT symptoms? Like hair loss, oilier skin, acne, etc?

I mentioned previously that I had worse hair loss on cypionate and propionate injections than cream, even though I had both higher free T and 10x higher DHT on the cream. I just confirmed this again -- I switched from cream back to injections, just 10 mg testosterone propionate daily, and immediately my hair starts falling out. WTF? It is a real head scratcher (Lol get it, a head scratcher) and 180 degrees opposite of what you would expect.

I guess I'm going to try cream again at a lower dose, maybe on inner thigh for a bit less absorption than scrotum.

 

I mentioned previously that I had worse hair loss on cypionate and propionate injections than cream, even though I had both higher free T and 10x higher DHT on the cream. I just confirmed this again -- I switched from cream back to injections, just 10 mg testosterone propionate daily, and immediately my hair starts falling out. WTF? It is a real head scratcher (Lol get it, a head scratcher) and 180 degrees opposite of what you would expect.

I guess I'm going to try cream again at a lower dose, maybe on inner thigh for a bit less absorption than scrotum.

You don’t think the GERD while being on cream could have just been coincidence ? I hope for your sake it was cause seems like cream is much better overall for you as well.

I’m so suprised I’m actually able to up my dose and get symptom relief without any side effects. On injections the more I went up the worse I would feel. I could only keep my trough numbers around 450-500.

 

I mentioned previously that I had worse hair loss on cypionate and propionate injections than cream, even though I had both higher free T and 10x higher DHT on the cream. I just confirmed this again -- I switched from cream back to injections, just 10 mg testosterone propionate daily, and immediately my hair starts falling out. WTF? It is a real head scratcher (Lol get it, a head scratcher) and 180 degrees opposite of what you would expect.

I guess I'm going to try cream again at a lower dose, maybe on inner thigh for a bit less absorption than scrotum.

This is why I put so much emphasis on real world results. Yes ur an N of 1 case study, but I would assume that if a guy posed the question of whether they would hypothetically experience more hair loss with a DHT of say 100 on cyp or prop, or a DHT of 300 on the cream, most guys would reply that he would without a doubt experience more hair loss on the cream with a DHT of 300. So thanks for reporting ur experience. This is why its so valuable to have people experimenting and reporting their findings/ experiences

Any idea whether u experienced more hair loss on prop than cyp, or vice versa? And also, do u experience any noticeable hair loss on the cream, or basically none that ur aware of?

 

You don’t think the GERD while being on cream could have just been coincidence ? I hope for your sake it was cause seems like cream is much better overall for you as well.

I’m so suprised I’m actually able to up my dose and get symptom relief without any side effects. On injections the more I went up the worse I would feel. I could only keep my trough numbers around 450-500.

I don't think it's coincidence, but I'll try again and we'll see. Like you, I am otherwise able to tolerate and feel good at much higher free T on cream than injections.

 

This is why I put so much emphasis on real world results. Yes ur an N of 1 case study, but I would assume that if a guy posed the question of whether they would hypothetically experience more hair loss with a DHT of say 100 on cyp or prop, or a DHT of 300 on the cream, most guys would reply that he would without a doubt experience more hair loss on the cream with a DHT of 300. So thanks for reporting ur experience. This is why its so valuable to have people experimenting and reporting their findings/ experiences

Any idea whether u experienced more hair loss on prop than cyp, or vice versa? And also, do u experience any noticeable hair loss on the cream, or basically none that ur aware of?

I agree with the emphasis on real world results. I have been humbled by many wrong theories that led me astray over the years.

I couldn't tell much difference between cypionate and propionate, it was just alot of hair loss relative to baseline. Let's call it roughly 4x as much as normal.

If there is any additional hair loss at all on cream, it is minimal and hard to detect. Maybe something like 1.3x normal rate.

 

I agree with the emphasis on real world results. I have been humbled by many wrong theories that led me astray over the years.

I couldn't tell much difference between cypionate and propionate, it was just alot of hair loss relative to baseline. Let's call it roughly 4x as much as normal.

If there is any additional hair loss at all on cream, it is minimal and hard to detect. Maybe something like 1.3x normal rate.

When I was 24 my hair started thinning a little up top. (Before low t) the. Around 26 my t levels crashed. From then on my hair thinning really has not increased much. Trt hasn’t seemed to accelerate it at all

 

I don’t recommend an anal application for you because it increases the risk of transference and you wouldn’t want that

Hey don't ever say I didn't try to bury the hatchet with you. But you do need to repent for your hematologic crimes against humanity.

Also I did not give you proper props for above. That was good one! Too bad I can't get deep in the technical weeds with the world's current cream expert with most experience.

It is lonely for me sometimes. And I was going to share my graphs with you. I have so much I want to give.

 

You being a patient of Dr. Says explains why you don’t know anything about the cream and have so many questions. Shouldn’t you be posting your questions to Dr. Saya himself instead of on forums?

@RobRoy, that's a fair point. But, here I am getting ready to ask another question! I think you mentioned way back in the thread (or maybe I read this somewhere else), there is an occasional guy who needs TID dosing. How common is this? Rare?

I ask because I have been using cream for several months. I have varied dosing, but have mostly done twice a day - after AM shower and around 3-5 PM. But, I have been absolutely hitting a wall around noon consistently. Extreme fatigue around that time that lingers for hours or even the rest of the day. I have been trying to troubleshoot the cause and have not gotten a definitive answer yet (systematically eliminating one variable at a time).

One (admittedly unlikely) explanation is that between my AM dose and noon, I have absorbed, metabolized and excreted enough cream to feel the drop, which brings me to my question of considering TID dosing. I could simply try it, but was wondering how common it has been in your experience?

 

@RobRoy, that's a fair point. But, here I am getting ready to ask another question! I think you mentioned way back in the thread (or maybe I read this somewhere else), there is an occasional guy who needs TID dosing. How common is this? Rare?

I ask because I have been using cream for several months. I have varied dosing, but have mostly done twice a day - after AM shower and around 3-5 PM. But, I have been absolutely hitting a wall around noon consistently. Extreme fatigue around that time that lingers for hours or even the rest of the day. I have been trying to troubleshoot the cause and have not gotten a definitive answer yet (systematically eliminating one variable at a time).

One (admittedly unlikely) explanation is that between my AM dose and noon, I have absorbed, metabolized and excreted enough cream to feel the drop, which brings me to my question of considering TID dosing. I could simply try it, but was wondering how common it has been in your experience?

Have you ever pulled labs at that time ?

 

Have you ever pulled labs at that time ?

Good question and it's exactly what I need to do. Only reason I have not is I want labs after I have been doing the exact same protocol for several weeks. I tend to make small modifications more frequently than I should. Guilty as charged.

 

Good question and it's exactly what I need to do. Only reason I have not is I want labs after I have been doing the exact same protocol for several weeks. I tend to make small modifications more frequently than I should. Guilty as charged.

More than likely it’s not a dip in t (at least in the blood ) you respond pretty well to the cream. I don’t respond as well and I don’t have the energy dips. Like today I put more on in the morning and skipped my evening dose and still feel the same

 

More than likely it’s not a dip in t (at least in the blood ) you respond pretty well to the cream. I don’t respond as well and I don’t have the energy dips. Like today I put more on in the morning and skipped my evening dose and still feel the same

You still on the cream? I thought I remembered you saying something about going back to shots…I’ve been thinking about another run with the cream and being more patient with it. I felt better in most ways except erectile function seems to go to shit….curious if it will correct if I give it more time…

 

You still on the cream? I thought I remembered you saying something about going back to shots…I’ve been thinking about another run with the cream and being more patient with it. I felt better in most ways except erectile function seems to go to shit….curious if it will correct if I give it more time…

Yes I’m still on it. It just works best for me. My erections are fantastic on the cream. And daily tadalafil makes it even better. I forget your story but have you ever pulled labs on cream ? If so what did your levels look like?

 

Yes I’m still on it. It just works best for me. My erections are fantastic on the cream. And daily tadalafil makes it even better. I forget your story but have you ever pulled labs on cream ? If so what did your levels look like?

So u ended up staying on the cream? No injections whatsoever?

I remember u saying the cream seemed to stop working for u. Did all that resolve itself? If so, did u have to switch anything up to feel good again?

 

So u ended up staying on the cream? No injections whatsoever?

I remember u saying the cream seemed to stop working for u. Did all that resolve itself? If so, did u have to switch anything up to feel good again?

It did not stop working. I just had a return of what I thought were side effects of the injections. mainly headaches and mood issues. But all the other benefits remained.

I took one shot and then said to myself “you’re really gonna switch all this shit up again when you feel decent“. And then I would be chasing labs again and starting from scratch. On cream I have good recovery, Feel great at hockey, Sex drive and erections are great. So why mess with that. I’m chasing something that might be unrelated to trt, Or just trt in general. I was almost at a point where I completely stopped thinking about trt/hrt. i would like to get back to that place.

 

It did not stop working. I just had a return of what I thought were side effects of the injections. mainly headaches and mood issues. But all the other benefits remained.

I took one shot and then said to myself “you’re really gonna switch all this shit up again when you feel decent“. And then I would be chasing labs again and starting from scratch. On cream I have good recovery, Feel great at hockey, Sex drive and erections are great. So why mess with that. I’m chasing something that might be unrelated to trt, Or just trt in general. I was almost at a point where I completely stopped thinking about trt/hrt. i would like to get back to that place.

Gocha. So would u say that ur currently not feeling as good as u did the first few months on the cream, but pretty close? Or ur basically feeling as good as u did when starting the cream? Just want to clarify

overall it sounds like ur currently doing pretty damn good. Might not be 100%, from the sounds of it, but feeling good enough to not worry about tweaking anything protocol wise is honestly a great place to be, and pretty much the goal for most of us I would assume

 

Yes I’m still on it. It just works best for me. My erections are fantastic on the cream. And daily tadalafil makes it even better. I forget your story but have you ever pulled labs on cream ? If so what did your levels look like?

I don’t handle high levels on injections very well, so I started with 50 mg 2x day….was around 1200 w FT at 30, DHT was 250, E2 at upper 50s….dropped down to just one click a day and was 720 total 5 hrs after application….