New thoughts on sleep

DragonBits

Well-Known Member
I don't think this has ever been discussed, but it might be important for those of us that often wake up from sleep.

Oral contraceptive contain estrogen and progestin, (progestin is an analog of progesterone) which have been shown to increase the elimination half life of caffeine from 5-6 hours up to 10.7 hours.

Since many of use add in hormones like progesterone, and our estrogen levels varies, the eliminate half life of caffeine will also vary.

10-11 hours for caffeine elimination means one should not consume caffeine after what, 10AM? A lot different than I assumed should be 5 hours for caffeine half life.

Caffeine is in a lot of things, this is something to think about.
 

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Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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