Kyzatrex vs Maximus Native T

[busydad]

Is there any real difference between these 2 forms of oral testosterone? Do they have different half-life's? Does one seem more effective? I'm taking Maximus oral T at the moment 800 mg in the morning. I've been thinking about splitting the dose to 400 in the morning and 400 around lunch time. It seems like this is the normal dosing routine for the Kyzatrex, and I'm wondering if it will also work with the Native-T

 

[Guided_by_Voices]

I thought they were the same thing? Maximus has done a bit of a disservice IMO with the "Native T" terminology.

 

[FunkOdyssey]

They are not the same thing. Native testosterone is simply testosterone without chemical modification. Testosterone undecanoate modifies testosterone by attaching the undecanoate ester.

Cue someone rushing to reply, "but testosterone undecanoate yields the same bioidentical testosterone molecule when the body removes the ester!" Sure, but until that happens, it's a different molecule with different behavior, otherwise known as "not the same thing".

The half lives are comparable. Testosterone undecanoate is associated with a higher incidence of gastrointestinal complaints. Efficacy is similar.

It seems like this is the normal dosing routine for the Kyzatrex, and I'm wondering if it will also work with the Native-T

This scenario would require you to obtain multiple prescriptions for the same schedule III substance from multiple providers. Bad things happen at many levels (legal, medical, insurance, provider trust) when you get caught doing this, so no, these different forms of testosterone do NOT work together.

Maximus has done a bit of a disservice IMO with the "Native T" terminology.

Native testosterone is the term found in the published studies that exist using oral testosterone base. We did not coin the term ourselves. Maximus is an evidence-based, "follow the science" type of organization, so taking our cues from medical literature is the only coherent option for us.

 

[busydad]

I meant splitting the dose in half have taking 400mg in the morning and 400mg at lunch.

 

[FunkOdyssey]

I meant splitting the dose in half have taking 400mg in the morning and 400mg at lunch.

I misread that, sorry. Consult with your Maximus provider, but yes, that works fine in many cases. Roughly 90% of patients stay with the single morning dose and 10% opt for split dosing like you're proposing.

 

[Cataceous]

...
Cue someone rushing to reply, "but testosterone undecanoate yields the same bioidentical testosterone molecule when the body removes the ester!" Sure, but until that happens, it's a different molecule with different behavior, otherwise known as "not the same thing".

The half lives are comparable. Testosterone undecanoate is associated with a higher incidence of gastrointestinal complaints. Efficacy is similar.
...

Let's ask a different question then. Aside from the possible GI link, have any clinically significant differences been found? If not then the whole "native T" thing still seems like marketing obfuscation to me.