Issues with estradiol makes no sense. High estradiol but I feel well.

Ribeye

Active Member
So my labs come in, total T is fairly high at 1150, and free T is also up there at 335. Also taking 100mg of DHEA a day. Estradiol comes in at 245. Bottom line at the moment, I feel really good, other than still having some ED issues, that have admittedly greatly improved with the HRT therapy. If I feel ok, and my labs continue to otherwise be reasonable (CBC shows hemoglobin and hematocrit borderline or slightly high, but since I stopped taking finasteride I will soon be able to donate blood) Otherwise labs are very good. Same with Thyroid. So since I feel well, actually quite good, should I be concerned about the estradiol? If yes, should I cut down the dose of the HRT cream, or talk to my doc about AI's? I will say each time I went up in dose on HRT, it seemed libido increased, ED got better, energy increased, nothing but good things. what to do about estradiol is the only issue?
 
Estradiol comes in at 245.
Ultrasensitive?

How long were you on finasteride?

What is your current DHEA and DHT?


What is your TSH?

Watch this video:

 
So since I feel well, actually quite good, should I be concerned about the estradiol? If yes, should I cut down the dose of the HRT cream, or talk to my doc about AI's? I will say each time I went up in dose on HRT, it seemed libido increased, ED got better, energy increased, nothing but good things. what to do about estradiol is the only issue?
No. I would not do a thing. But let me know how high is your DHEA.

 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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