Therapy change

Roadkill

New Member
I've included my labs. At the time I was on .32 ml (200mg/ml) twice a week in addition to .4 ml HCG (12000 IU) 3 times a week. I was also taking 300mg DIM every day with a vitamin D supplement. I was only taking the HCG because my wife and I were trying to conceive but we have been successful since.

I, as well as the doc, were concerned about my estradiol levels during our last consult. He advised me to lower the HCG to .2 ml 3 times a week and to start taking arimidex 1/4 of a 1 mg tablet once a week. I recently read some posts that state never to start an AI. I have a couple of concerns.

1. During the last 2 years of being on TRT I have never really noticed a difference in the way I feel. I do know that there has been some physical change because I get comments all the time about my physique. I've expressed this during my last 2 consults but haven't really had any clarification as to why this might be. Should I be concerned that I'm not feeling "better"?

2. What are the concerns with taking an AI? What things should I look out for as signs of negative reaction? Obviously my estradiol is high. How else could I manage this?
 

Attachments

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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