How high is too high?

sirgawain

Member
I just got back from my annual physical. My doctor asked about my TRT. He's a reasonable guy and won't argue, but his one comment was that he thought 1100 at the low was "probably a bit high." But he won't lecture me.

Thoughts? I have no idea what my high is if the 1100 is my low. I inject 3.5 2x a week sub-q as well as ReliableRX secured HCG (.5 2x a week). I used to do 7 IM once a week.

My last labs were in March with this exact protocol:

T: 1137
E: 38
SHBG: 38.1
 
My last labs were in March with this exact protocol:

T: 1137
E: 38
SHBG: 38.1
Yeah, that's probably too high. @readalot has a formula to calculate your approximate peak values based on your trough. I would guess that you are peaking around 1600 ng/dl total and 60 ng/dl free. Even TOT guidelines for free T will often use 50 ng/dL as a cutoff for the top end.
 
I would guess that you are peaking around 1600 ng/dl total and 60 ng/dl free
I agree with the TT prediction, but I doubt his FT is that high especially on 2x/week injections. His SHBG is the same as mine and when my TT was 1800ng/dL on daily injections my FT was only 36ng/dL.

OP, make sure you get Free T tested and test your peak values also if you're interested. Those are not crazy numbers but you're definitely peaking significantly above the range at least for TT. Is that bad long term? Nobody knows, but my guess is that it's probably not quite as healthy as 800ng/dL TT and 18ng/dL FT troughs long term
 
I agree with the TT prediction, but I doubt his FT is that high especially on 2x/week injections. His SHBG is the same as mine and when my TT was 1800ng/dL on daily injections my FT was only 36ng/dL.

You're right, I read the E: 38 in his post as Free T: 38 ng/dL somehow. His calculated free T at trough looks to be 26.4 ng/dL and I would guess it is closer to 40 ng/dL at peak. That's higher than many here would be comfortable with but those are typical TOT values. I would say reducing the dose then depends on your risk tolerance and how you are feeling.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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