Hormone replacement therapy: practical applications and the role of compounding pharmacies

Nelson Vergel

Founder, ExcelMale.com
Dr Attia discusses:
  1. Why hormone replacement therapy is such an important topic [2:00];
  2. The onset of menopause: symptoms, blood tests, and when to consider HRT [6:00];
  3. Tests that may provide indications of perimenopause and their implications for fertility [9:15];
  4. Vasomotor symptoms: hormonal changes that cause hot flashes/night sweats, and HRT therapies that can help [13:45];
  5. The role of estrogen in menopausal HRT [17:30];
  6. The limited role of progesterone in HRT protocols [25:15];
  7. What is a “bioidentical” hormone? [28:30];
  8. Overview of the FDA-approved HRT formulations [31:45];
  9. Determining HRT dosing and considerations for perimenopausal women [37:45];
  10. Choosing the right HRT formulation: pros and cons [43:30];
  11. Examining the link between certain forms of estrogen and breast cancer [46:45];
  12. Changes in testosterone levels in women over time and why it matters [50:00];
  13. Recognizing low testosterone in women: common symptoms and diagnosis [53:45];
  14. Testosterone replacement therapy for women: options, considerations, and challenges [57:30];
  15. The long-term use of testosterone in women: examining the limited data [1:00:15];
  16. What is a compounding pharmacy? [1:09:30];
  17. Reasons to opt for a compounding pharmacy over a pharmacy that adheres to stricter regulations [1:16:00];
  18. The tragic incidents that heightened concerns about compounding pharmacies [1:20:45];
  19. Tips for finding a reputable compounding pharmacy [1:27:45]; and
More. @everyone

https://peterattiamd.com/ama52/
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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