help plz

ukguy

New Member
I have been on TRT since 1993, since my own testicles stopped all production of testosterone at age 45.

I had a DVT (deep venous thrombosis) when I had a PICC line for antibiotics in 2007. Same vein as the line so likely caused by the line. Treated with Coumadin for 6 months and the clot resolved. I have remained on TRT continuously since 1993. 3 years ago I added Arimidex due to high estrogen levels.

I have never had another DVT. I have had to have 3 coronary stents placed due to artery stenosis since 2000, but I have a horrible familial history of coronary artery disease. So I don't know if my CAD can be blamed on the TRT?

I know my quality of life is greatly enhanced from the TRT as I well recall how miserable life was when I had no testosterone in my body. You have to weigh the risk vs. the benefits. When my T was low, not only did I have no libido but I was severely depressed, constantly fatigued, suffered from constant panic attacks and anxiety to the point my life was miserable. With my first injection of T, I was a changed man and none of those symptoms have ever reoccurred. To me it is not even a question as whether to continue the TRT. When my Cardiologist demanded I stop the TRT in 2000, following my first stent, I plainly told him I would rather be dead than live without testosterone. He has never brought the subject up again. 14 years later, I certainly don't regret my decision to continue the TRT.

With a history of DVT, if you are just looking to jack up your testosterone even though your natural level is normal or near-normal, then I say it is contraindicated. If your endogenous testosterone is low and it is drastically affecting your quality of life, then you have to decide if the benefits outweigh the risks? I would rather live a shorter happy life than live a long miserable life.


Hello

I have also been on trt for several years now, and without it i am exactly like you described how you felt also before you started trt. However last month i had a discectomy (partial removal of disc l4/l5 to relieve severe sciatica pain i had been suffering from for 2 years. the surgery was a success but 6 days later i suffered a pulmonary embolism(blood clot on lung) due to the hospital deciding that i wasn't a risk for clotting after surgery so i didn't required any blood thinners. so basically i was very unlucky and developed the clot probably due to being so immobile after the surgery in thinking it would help heal the disc/surgery better. anyway i stopped my trt a 3 weeks before the surgery and haven't had any trt now for 6 weeks and the terrible symptoms from low testosterone have hit me like a tonne of bricks, i am healing very well after the surgery and lung clot set back but mentally and physiologically i am distraught, to the point that over the last few days i have felt so low i am in constant fear. i have decided that life without trt is not going to work at all for me, but i am still on blood thinners for the next 6 weeks, its called apixaban and i am worried that a) if i restart my trt it might have an effect on the blood thinners or for all i know it might help? and b) if the trt even on 150mg testosterone per week (which was my usual dose) will put me at risk of another clot? i have read conflicting information but the bottom line is i simply cant carry on living the way i feel so regardless of the risk i think i will have to restart my trt asap. and the fact that the only blood clot i have ever had was a provoked clot from the surgery leads me to think that i am not specifically at risk from developing another clot from trt.
any help or advise will be much appreciated.
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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