Gene's Nitric Oxide Stack

Many have used this stack for massive hard pumps in the gym, significant vascularity and excellent erectile function not discounting the health benefits. If you're looking for any of these benefits and more...give it a try!

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)


nitric oxide excelmale.webp

Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)



More Than a Muscle Pump: The Surprising Science of the Nitric Oxide Stack

In the biohacking world, we often chase complex peptides or experimental compounds, but we frequently overlook the most fundamental currency of life: blood flow. In the quest for longevity, systemic vascular efficiency is the baseline upon which all other health markers are built. As we age, our ability to maintain vasodilatory capacity diminishes, impacting everything from cognitive sharpness to metabolic health. "Gene’s Nitric Oxide Stack," a protocol born and refined within the ExcelMale community, has emerged as a definitive solution for men seeking to optimize this system. This isn't just a gym supplement routine; it is a sophisticated approach to anti-aging that leverages amino acids and targeted pharmaceutical interventions to restore the body’s most vital delivery mechanism.

Beyond the Mirror: The Science of the Sustained Pump​

For the average gym-goer, the "pump" is a transient aesthetic goal—a fleeting moment of muscle fullness. However, for a longevity specialist, a "harder pump" and increased vascularity are indicators of high-functioning endothelial health. The Nitric Oxide Stack is engineered to produce a state of vasodilation that doesn't simply vanish when you rack the weights.

By optimizing the nitric oxide signaling pathway, this protocol facilitates a sustained pump that carries through your daily life. This is a critical distinction: the visual vascularity is a proxy for your body’s ability to keep its "pipes" open. When you maintain that fullness hours after a workout, you are essentially providing proof of concept that your circulatory system is operating at peak efficiency, ensuring constant nutrient delivery to peripheral tissues.

The Foundation of Performance: Hard Science for Sexual Vitality​

One of the most immediate benefits of systemic vasodilation is the restoration of sexual function. From a clinical perspective, erection quality is often the "canary in the coal mine" for cardiovascular health. Because the Nitric Oxide Stack focuses on the root physiological requirements of performance—blood flow and retention—it provides a robust alternative to temporary fixes.

A Serious Solution for Erection Quality and Duration

This stack addresses both the quality and the duration of erections with clinical precision. For men navigating the aging process, this is not a matter of vanity, but of maintaining vital physiological function. By ensuring the vascular system can respond effectively to neurological signals, the protocol allows for a level of performance that many mistakenly believe is lost to time.

The Ultimate Nootropic: Future-Proofing the Neocortex​

Perhaps the most compelling argument for nitric oxide optimization is the "bodybuilder to brain health" pipeline. While most men start this stack for its physical benefits, they are unknowingly deploying a powerful shield against age-related cognitive decline. As we age, the micro-vasculature within the brain tends to narrow and tighten, a process that starves the brain of oxygen and is a primary driver of age-related dementia.

The stack acts as a nootropic by ensuring that the brain's smallest vessels remain dilated and resilient. This ensures that the neocortex and other critical regions receive a constant supply of the nutrients required for cognitive longevity. As the source material highlights:

"by increasing nitric oxide and getting that vascular dilation we're getting oxygen blood and nutrients in the areas of the brain that can provide us with a great anti-aging benefit in terms of neurological health."

The irony is profound: a protocol often associated with the bicep curl may actually be one of your most effective tools for protecting your mind.

Systemic Management: Blood Pressure and Prostate Function​

The benefits of the stack extend into the deeper mechanics of men’s health, specifically regarding the relaxation of smooth muscle tissue. This is particularly relevant for Benign Prostate Hyperplasia (BPH) and blood pressure management. Nitric oxide serves as a signal for these tissues to relax, directly easing the "inability to ease the problems" that typically characterize age-related prostate issues.

The secondary physiological advantages of this systemic relaxation include:

  • Vascular Tension Reduction: Significant support for maintaining healthy blood pressure levels by reducing resistance within the arterial walls.
  • Prostate Relief: Improvement in quality of life by relaxing the prostatic smooth muscle, easing the mechanical symptoms of BPH.
  • Reduced Cardiac Load: By improving systemic flow, the heart is not required to pump against the same level of resistance, preserving cardiovascular longevity.

The Future of Your Vascular Health​

"Gene’s Nitric Oxide Stack" is far from a theoretical exercise; it is a "living protocol" backed by years of community peer-review within the ExcelMale community. The "enormously long" and widely viewed thread on ExcelMale.com serves as a testament to the real-world efficacy of this stack, offering a repository of shared experiences and optimization strategies.

This multi-front approach to anti-aging represents the best of biohacking: using fundamental biological pathways to solve complex aging problems. By focusing on the delivery system itself, we can protect our brains, our hearts, and our vitality simultaneously.

If blood flow is the delivery system for every nutrient your body needs, what happens to your longevity when you finally optimize that system?


More on Nitric Oxide in Men:

Nitric Oxide Pages
 
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Thanks for the super reply Loki!!!

No problem!!! If you try this routine start slow... Maybe 10-12 sets per muscle group and 8-10 reps per set. Work your way up... Add in sets and reps and you get stronger. I have a guy who has been training for a few months and he went from a chubby IT guy to benching 335. At first his weight went up (adding muscle) and now its shedding off(fat and weight)...

On the diet I mainly eat balanced and clean. I can't do Keto and I can't really cycle the way I eat (any type of actual diet). For example here is what I will eat today-

Breakfast -

Oatmeal, Orange, Banana and a protein bar. Water with some probiotics mixed in (taste really good)

Snack before lunch - More water and some men's health nuts.

Lunch-

Water, Cranberry chicken salad sandwich with a bowl of turkey chilli.


Snack before I go home- Orgain protein shake (more like a meal replacement carbs and protein are balanced)

Dinner

Turkey spaghetti with corn, green beans and a salad. I will probably drink water as that is what I like the most out of habit...

Possibly some nuts, fruit or another snack before bed...
 
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Great work out,. The reps are something similar to what I have seen VIctor Black recommend. Couple for questions:
1 - how close to failure are you getting on these sets?
2 - How much rest between sets. For example, if I do a 20 rep set to true failure, a one minute rest will get me to only 10 reps on the next set with the same weight.
3 - are you increasing the weight with each set. This is kind of related to #2. That is - if I go anywhere near failure on a set of 20 and had to increase the weight on the next set and the next set was 15 reps, I would have to rest a long time
4 - Do you keep this template indefinitely and just rotate the exercises

Thanks in advance
 
Great work out,. The reps are something similar to what I have seen VIctor Black recommend. Couple for questions:
1 - how close to failure are you getting on these sets?
2 - How much rest between sets. For example, if I do a 20 rep set to true failure, a one minute rest will get me to only 10 reps on the next set with the same weight.
3 - are you increasing the weight with each set. This is kind of related to #2. That is - if I go anywhere near failure on a set of 20 and had to increase the weight on the next set and the next set was 15 reps, I would have to rest a long time
4 - Do you keep this template indefinitely and just rotate the exercises

Thanks in advance

1) My muscular conditioning is off the charts. I can rep 225 55-60 reps. 315 for 21 reps. So in the end of my workout I always go to failure but the other sets are challenging just not to failure. You could always adjust those reps to 12-15 and build up to the 20-30 rep sets. It is like anything else it just takes training to get there.

2) I rest 1-2 minutes. If I am setting a PR on heavy weight or on a rep I may give myself some extra time. It is amazing though how when you train like this how your body adapts.

3) I always increase when I pyramid 12, 10,8, 6, 4. On triceps when I warm up with 135 I will do 2 sets of 30 and then my remaining 4 sets of 20 I stay at 225.

4) Certain core things I never change. I never do chest without doing flat and incline. Biceps I always do the single arm preacher curls. Shoulders always presses and raises. Triceps always do narrow bench. Back I always do pull ups. Legs always do some form of squats. So I do change it up but keep my core exercises going. For example I also like going to the cables and moving each side as high as possible. Then grab the cables and take one step forward. Then lock in my elbow position and curl my hands into my ears. This is a great double bicep curl exercise.

I have trained with some world record holders in bench press, combine record holders, etc... High volume training was always part of what they did... Plus you develop a different look... I call my reps and heavy weight power building. I think it's a more athletic version of body building... We are kicking around starting a youtube channel...
 
Workout routines are like so many other things, there's 100 people with 110 opinions on what works. What I can note in my gym is the people with their books and diaries trailing along behind seem to be the ones that make few gains. Just an observation. They seem locked in to Z movement with X weight for Y reps and that's all they do and it's what I observe and call "going thru the motions".
 
Not sure if this has been discussed but I notice a difference between L Arginine free form and HCL and AKG in the stack related to erection.

Free form = best
HCL = less effect
AKG = lower effect

I started reading on ways to mask the bad taste of freeform using grape juice and lemon, it is still a chore. I will try to find arginine tablets this week as I notice I avoid the stack due to taste. '

My question is would the HCL be as effective if I used more of it. For example I can notice a difference of 6g or Freeform vs 6g of HCL. But has anyone tried taking more of the HLC to try to get the same effect? Certainly there are digestive issue trade off's with arginine that must be considered.

Edit. I have never added the Doxazsin to the stack since it was not easy to go get off the shelf. Would this make an obvious impact on erection if I added it? I take amlodopan once in a while for blood pressure, doc said just stay on it but often I am not high so I try not to rely on it.
 
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Outside of however you feel and by all means you've got some interesting observations there, Arginine is a rather poor donor of NO when taken this way and I wouldn't waste too much time chasing that around as Citrulline is far superior in this regard as an NO donor.
 
So guys over a month in. Question, has anybody noticed increased liver enzymes with this stack, and sporadic mild back pain at times. My energy is also down some. I also get tinglingnin the finger tips when I sleep, and my knee joints hurt for the first time in all my life. I was blaming the arimidex at first .5mg x2 week. However on bloods estrogen was at 40 on the sensitive test that is protocol. Then I realized the only new things added was the stack which I removed all the herbal supplements weeks ago and just ran the cialis and doxazosin. However, I am thinking to discontinue the whole thing and see what happens. I did start cardio so I'm hoping that my pressure stays undercontrol. I am going to drop the doxazosin then the cialis if after 2 weeks no improvements. Doxazosin will be dropped tonight, no bedtime dose. Let me know if anyone else has had the side effects. I have a appt with my doc tomorrow to discuss it. I will tell you guys how I goes.
 
So guys over a month in. Question, has anybody noticed increased liver enzymes with this stack, and sporadic mild back pain at times. My energy is also down some. I also get tinglingnin the finger tips when I sleep, and my knee joints hurt for the first time in all my life. I was blaming the arimidex at first .5mg x2 week. However on bloods estrogen was at 40 on the sensitive test that is protocol. Then I realized the only new things added was the stack which I removed all the herbal supplements weeks ago and just ran the cialis and doxazosin. However, I am thinking to discontinue the whole thing and see what happens. I did start cardio so I'm hoping that my pressure stays undercontrol. I am going to drop the doxazosin then the cialis if after 2 weeks no improvements. Doxazosin will be dropped tonight, no bedtime dose. Let me know if anyone else has had the side effects. I have a appt with my doc tomorrow to discuss it. I will tell you guys how I goes.

Hi Nyce, You have just listed all the negative side effects of cialis. The only thing you did not list was stuffy nose.
On a side note I just ordered some LEVITRA to test out in place of the cialis. It is not suppose to have the same bad sides.
I am aware of the shorter half life and that low dose is not FDA approved.

I just finished an experiment where I only took 5mg of cialis split in two doses and I lost most of the NO effects. 5mg x2 daily gives me a far better pump in the gym and bedroom. But I have to use nasel spray every 6-8 hours when on 10mg.
 
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How likely would you guys be to trust a nitric oxide supplement designed by ExcelMale? I am thinking about our own line of evidence-based supplements. Thanks

This was my first stack based on this thread.

37663253322_7b34cc1e77.jpg


I quickly realized do to the quanities in grams required multiple times a day I could not keep buying these tiny pill bottles. This stack was just too expensive.
Bulk supplements are needed to make this cost effective. I do believe those of us using Gene's stack or a modified version of it for any extended period of time buy in bulk.

38014975876_9afcbf98d6.jpg


So I guess what I am saying is I would not buy unless I saw results and could buy bulk quanities at a reasonable price.

I also have to assume you would not be adding prescription drugs like Tadalafil (Cialis) or Doxazosin (Alpha Blocker) which according to Gene is the magic of this stack all other supplements are only supporting. Which tells me they are optional.
 
Unlikely you can beat the prices of buying in bulk and the market, I think, is saturated with premade and overpriced stuff as it is. One thing you could take advantage of is not having proprietary blends of leaves and twigs (that's a joke) in a product, fillers, and using clinically effective doses of Citrulline, Creatine, Arginine, Beta Alanine, or whatever else.
 

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