Gene's Nitric Oxide Stack

Many have used this stack for massive hard pumps in the gym, significant vascularity and excellent erectile function not discounting the health benefits. If you're looking for any of these benefits and more...give it a try!

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)

Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)

More Than a Muscle Pump: The Surprising Science of the Nitric Oxide Stack​

In the biohacking world, we often chase complex peptides or experimental compounds, but we frequently overlook the most fundamental currency of life: blood flow. In the quest for longevity, systemic vascular efficiency is the baseline upon which all other health markers are built. As we age, our ability to maintain vasodilatory capacity diminishes, impacting everything from cognitive sharpness to metabolic health. "Gene’s Nitric Oxide Stack," a protocol born and refined within the ExcelMale community, has emerged as a definitive solution for men seeking to optimize this system. This isn't just a gym supplement routine; it is a sophisticated approach to anti-aging that leverages amino acids and targeted pharmaceutical interventions to restore the body’s most vital delivery mechanism.

Beyond the Mirror: The Science of the Sustained Pump​

For the average gym-goer, the "pump" is a transient aesthetic goal—a fleeting moment of muscle fullness. However, for a longevity specialist, a "harder pump" and increased vascularity are indicators of high-functioning endothelial health. The Nitric Oxide Stack is engineered to produce a state of vasodilation that doesn't simply vanish when you rack the weights.

By optimizing the nitric oxide signaling pathway, this protocol facilitates a sustained pump that carries through your daily life. This is a critical distinction: the visual vascularity is a proxy for your body’s ability to keep its "pipes" open. When you maintain that fullness hours after a workout, you are essentially providing proof of concept that your circulatory system is operating at peak efficiency, ensuring constant nutrient delivery to peripheral tissues.

The Foundation of Performance: Hard Science for Sexual Vitality​

One of the most immediate benefits of systemic vasodilation is the restoration of sexual function. From a clinical perspective, erection quality is often the "canary in the coal mine" for cardiovascular health. Because the Nitric Oxide Stack focuses on the root physiological requirements of performance—blood flow and retention—it provides a robust alternative to temporary fixes.

A Serious Solution for Erection Quality and Duration

This stack addresses both the quality and the duration of erections with clinical precision. For men navigating the aging process, this is not a matter of vanity, but of maintaining vital physiological function. By ensuring the vascular system can respond effectively to neurological signals, the protocol allows for a level of performance that many mistakenly believe is lost to time.

The Ultimate Nootropic: Future-Proofing the Neocortex​

Perhaps the most compelling argument for nitric oxide optimization is the "bodybuilder to brain health" pipeline. While most men start this stack for its physical benefits, they are unknowingly deploying a powerful shield against age-related cognitive decline. As we age, the micro-vasculature within the brain tends to narrow and tighten, a process that starves the brain of oxygen and is a primary driver of age-related dementia.

The stack acts as a nootropic by ensuring that the brain's smallest vessels remain dilated and resilient. This ensures that the neocortex and other critical regions receive a constant supply of the nutrients required for cognitive longevity. As the source material highlights:

"by increasing nitric oxide and getting that vascular dilation we're getting oxygen blood and nutrients in the areas of the brain that can provide us with a great anti-aging benefit in terms of neurological health."

The irony is profound: a protocol often associated with the bicep curl may actually be one of your most effective tools for protecting your mind.

Systemic Management: Blood Pressure and Prostate Function​

The benefits of the stack extend into the deeper mechanics of men’s health, specifically regarding the relaxation of smooth muscle tissue. This is particularly relevant for Benign Prostate Hyperplasia (BPH) and blood pressure management. Nitric oxide serves as a signal for these tissues to relax, directly easing the "inability to ease the problems" that typically characterize age-related prostate issues.

The secondary physiological advantages of this systemic relaxation include:

• Vascular Tension Reduction: Significant support for maintaining healthy blood pressure levels by reducing resistance within the arterial walls.
• Prostate Relief: Improvement in quality of life by relaxing the prostatic smooth muscle, easing the mechanical symptoms of BPH.
• Reduced Cardiac Load: By improving systemic flow, the heart is not required to pump against the same level of resistance, preserving cardiovascular longevity.

The Future of Your Vascular Health​

"Gene’s Nitric Oxide Stack" is far from a theoretical exercise; it is a "living protocol" backed by years of community peer-review within the ExcelMale community. The "enormously long" and widely viewed thread on ExcelMale.com serves as a testament to the real-world efficacy of this stack, offering a repository of shared experiences and optimization strategies.

This multi-front approach to anti-aging represents the best of biohacking: using fundamental biological pathways to solve complex aging problems. By focusing on the delivery system itself, we can protect our brains, our hearts, and our vitality simultaneously.

If blood flow is the delivery system for every nutrient your body needs, what happens to your longevity when you finally optimize that system?


More on Nitric Oxide in Men:

Nitric Oxide Pages

 

I don't think you are reading this right at all. This is for those of us that want to build a better body increase NO and also morning wood or wood overall. I don't read anything in this for BP of BPH but it should help both antidotally.

Sure. Please don't construe my question as any kind of critique. But I read on all these supplements constantly to get better informed on the bigger picture, and for example, Doxazosin is identified as being used specifically to treat BPH. I am one of those very sensitive to medications so I'm extremely cautious. In the past, I've had some major health issues triggered by prescribed medications. I've had one doctor said he's never seen anyone react to one med like I did.

As of now, I'm doing better the past few weeks just from upping my exercise, focusing on NO in the diet, and adding Coq10 - but it's good to have this NO stack baseline in case I need up my game. I really do appreciate the fact that folks such as Nelson and Gene are these as trail-blazers - this site has been invaluable.

 

Have my total supply now but the Tadalafil is 20mg and I have to cut those in half for a once a day use. Have 5mg coming but for now the 20mg but into 10mg is what I am doing. No wood yet but when I took the remaining Tadalafil I had it took a few days for the wood to pop up.
Will report results when I have some. If this doesn't get me on track will be doing TRT gel and HCG...

 

Sure. Please don't construe my question as any kind of critique. But I read on all these supplements constantly to get better informed on the bigger picture, and for example, Doxazosin is identified as being used specifically to treat BPH. I am one of those very sensitive to medications so I'm extremely cautious. In the past, I've had some major health issues triggered by prescribed medications. I've had one doctor said he's never seen anyone react to one med like I did.

As of now, I'm doing better the past few weeks just from upping my exercise, focusing on NO in the diet, and adding Coq10 - but it's good to have this NO stack baseline in case I need up my game. I really do appreciate the fact that folks such as Nelson and Gene are these as trail-blazers - this site has been invaluable.

If there is anything I've learned in helping men in this game is that we are all different and we all respond differently. Some men over respond to drugs where others need many time more in dosage to receive the same result.

Dr. John Crisler taught me this a long time ago and I see it over and over again in men and how they respond to different protocols.

My advise for over responders is to take it slow and titrate up slowly my stack to you find your sweet spot. The stack works, make no mistake about that, but if you over respond, take it slow and add in slowly till you get the result you are looking for.

This stack is so healthy for so many reasons and has so many benefits it's not
even funny!

 

Have my total supply now but the Tadalafil is 20mg and I have to cut those in half for a once a day use. Have 5mg coming but for now the 20mg but into 10mg is what I am doing. No wood yet but when I took the remaining Tadalafil I had it took a few days for the wood to pop up.
Will report results when I have some. If this doesn't get me on track will be doing TRT gel and HCG...

Give it a week or so till serum levels come up and stabilize you will see the results when you wake up in the morning.

I always suggest that men take the Cialis just before bed to see the best waking wood...it always works LOL!

Enjoy boys

 

Supplements work best at bedtime, unless they are:
* Energizing - and thus give you insomnia (CoQ10, or ALCAR for example)
and/or
* Best taken with food (fish oil or krill oil, most vitamins and minerals)

When you are asleep, the supplement can be absorbed and take effect without interference from meals or activity.

 

I am noticing some increase in veins and some wood improvement. Will stay the course and see what the results are. Feel like I have a little more stamina at the gym but I actually have been eating more as I am being told I am now too thin. I have no noted side effects from the stack and wanted to report that since I have been on it for around 2 weeks...

 

Dear Gene, I am having following queries:

1] Consuming alcohol is allowed or not while on this stack

2] Before going to make love, extra mg of Tadalafil is recommended or not

 

Dear Gene, I am having following queries:

1] Consuming alcohol is allowed or not while on this stack
A: I like my ****tails and it never had a neg effect on this stack.

2] Before going to make love, extra mg of Tadalafil is recommended or not

A: Yes, it you want and I have. Just take about 60 mins or so before activity on an empty stomach.

 

Dear Gene, I am having following queries:

1] Consuming alcohol is allowed or not while on this stack

2] Before going to make love, extra mg of Tadalafil is recommended or not

Alcohol does not affect the stack, but a quantity before making love does negatively affect "wood" (for anyone who was not aware of that). Same for caffeine, by the way - it is a "vasoconstrictor", while the stack is a "vasodilator".

I find that the Tadalafil is slow to go away and slow to take effect. So, if you are taking it twice a day, that should be sufficient. Some people say it can take 6 hours to take effect, and that seems right to me, so I would take that last dose 4-6 hours before.

Of course, everyone is different in these things, you have to use trial and error.

BTW, if you are still marginal in "wood", try the Beet Powder mentioned earlier in the thread by Gene and myself.

 

[quote from duke]I find that the Tadalafil is slow to go away and slow to take effect. So, if you are taking it twice a day, that should be sufficient. Some people say it can take 6 hours to take effect, and that seems right to me, so I would take that last dose 4-6 hours before.
Of course, everyone is different in these things, you have to use trial and error.



(I wonder if having food in your stomach would make Tadalafil take longer to take effect)

 

Cialis does not work for me until the next day and even the third day. Levitra is best for me for fast response.

If you are on daily 5 mg Cialis, that is best.

 

(I wonder if having food in your stomach would make Tadalafil take longer to take effect)

My pharmacist tells me that he gets this question regularly and advises men to see how their body responds. I find no difference, but I trust each person's own findings.

 

One more query:
Is this stack for every healthy man or only for those who workout?

 

One more query:
Is this stack for every healthy man or only for those who workout?

Every Male

 

One more query:
Is this stack for every healthy man or only for those who workout?

A truly healthy man who did not workout, would have no reason to ever take any pill in his life.

 

A truly healthy man who did not workout, would have no reason to ever take any pill in his life.

To each there own

My dad passed away last year at 95 never went to a gym or took a vitamin in his life

 

I am having GNC Horny Goat Weed which contain 600 mg of HGW and 250 mg of Maca Root Extract. So how to make HGW 150 mg. Moreover,I hope no problem with Maca to stack.

 

Dear Gene, I need to know the role of Doxazosin in the stack. As I know Tadalafil causes hypotension and Doxazosin does the same as well. So I am a bit confused. And also, what if Doxazosin is dropped in the stack?

 

Dear Gene, I am waiting for your response.

 

So Gene there's no doubt those supplements help but do you pretty much have to go workout for your vascularity to be pronounced like in the pics you posted?