Gene's Nitric Oxide Stack

Many have used this stack for massive hard pumps in the gym, significant vascularity and excellent erectile function not discounting the health benefits. If you're looking for any of these benefits and more...give it a try!

Nitric Oxide Stack
Bed Time
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)


Morning
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)

Afternoon
5 mg of Tadalafil (Cialis)
3000 mg of L-Arginine
1500 mg of L-Citrulline
50 mg of Pycnogenol
150 mg of Icariin (Horny Goat Weed)
1 mg of Doxazosin (Alpha Blocker)

More Than a Muscle Pump: The Surprising Science of the Nitric Oxide Stack​

In the biohacking world, we often chase complex peptides or experimental compounds, but we frequently overlook the most fundamental currency of life: blood flow. In the quest for longevity, systemic vascular efficiency is the baseline upon which all other health markers are built. As we age, our ability to maintain vasodilatory capacity diminishes, impacting everything from cognitive sharpness to metabolic health. "Gene’s Nitric Oxide Stack," a protocol born and refined within the ExcelMale community, has emerged as a definitive solution for men seeking to optimize this system. This isn't just a gym supplement routine; it is a sophisticated approach to anti-aging that leverages amino acids and targeted pharmaceutical interventions to restore the body’s most vital delivery mechanism.

Beyond the Mirror: The Science of the Sustained Pump​

For the average gym-goer, the "pump" is a transient aesthetic goal—a fleeting moment of muscle fullness. However, for a longevity specialist, a "harder pump" and increased vascularity are indicators of high-functioning endothelial health. The Nitric Oxide Stack is engineered to produce a state of vasodilation that doesn't simply vanish when you rack the weights.

By optimizing the nitric oxide signaling pathway, this protocol facilitates a sustained pump that carries through your daily life. This is a critical distinction: the visual vascularity is a proxy for your body’s ability to keep its "pipes" open. When you maintain that fullness hours after a workout, you are essentially providing proof of concept that your circulatory system is operating at peak efficiency, ensuring constant nutrient delivery to peripheral tissues.

The Foundation of Performance: Hard Science for Sexual Vitality​

One of the most immediate benefits of systemic vasodilation is the restoration of sexual function. From a clinical perspective, erection quality is often the "canary in the coal mine" for cardiovascular health. Because the Nitric Oxide Stack focuses on the root physiological requirements of performance—blood flow and retention—it provides a robust alternative to temporary fixes.

A Serious Solution for Erection Quality and Duration

This stack addresses both the quality and the duration of erections with clinical precision. For men navigating the aging process, this is not a matter of vanity, but of maintaining vital physiological function. By ensuring the vascular system can respond effectively to neurological signals, the protocol allows for a level of performance that many mistakenly believe is lost to time.

The Ultimate Nootropic: Future-Proofing the Neocortex​

Perhaps the most compelling argument for nitric oxide optimization is the "bodybuilder to brain health" pipeline. While most men start this stack for its physical benefits, they are unknowingly deploying a powerful shield against age-related cognitive decline. As we age, the micro-vasculature within the brain tends to narrow and tighten, a process that starves the brain of oxygen and is a primary driver of age-related dementia.

The stack acts as a nootropic by ensuring that the brain's smallest vessels remain dilated and resilient. This ensures that the neocortex and other critical regions receive a constant supply of the nutrients required for cognitive longevity. As the source material highlights:

"by increasing nitric oxide and getting that vascular dilation we're getting oxygen blood and nutrients in the areas of the brain that can provide us with a great anti-aging benefit in terms of neurological health."

The irony is profound: a protocol often associated with the bicep curl may actually be one of your most effective tools for protecting your mind.

Systemic Management: Blood Pressure and Prostate Function​

The benefits of the stack extend into the deeper mechanics of men’s health, specifically regarding the relaxation of smooth muscle tissue. This is particularly relevant for Benign Prostate Hyperplasia (BPH) and blood pressure management. Nitric oxide serves as a signal for these tissues to relax, directly easing the "inability to ease the problems" that typically characterize age-related prostate issues.

The secondary physiological advantages of this systemic relaxation include:

• Vascular Tension Reduction: Significant support for maintaining healthy blood pressure levels by reducing resistance within the arterial walls.
• Prostate Relief: Improvement in quality of life by relaxing the prostatic smooth muscle, easing the mechanical symptoms of BPH.
• Reduced Cardiac Load: By improving systemic flow, the heart is not required to pump against the same level of resistance, preserving cardiovascular longevity.

The Future of Your Vascular Health​

"Gene’s Nitric Oxide Stack" is far from a theoretical exercise; it is a "living protocol" backed by years of community peer-review within the ExcelMale community. The "enormously long" and widely viewed thread on ExcelMale.com serves as a testament to the real-world efficacy of this stack, offering a repository of shared experiences and optimization strategies.

This multi-front approach to anti-aging represents the best of biohacking: using fundamental biological pathways to solve complex aging problems. By focusing on the delivery system itself, we can protect our brains, our hearts, and our vitality simultaneously.

If blood flow is the delivery system for every nutrient your body needs, what happens to your longevity when you finally optimize that system?


More on Nitric Oxide in Men:

Nitric Oxide Pages

 

DanJ - First and foremost welcome to the ExcelMale community; glade to have you.

Ok, we all know that 25 year old otherwise health guys shouldn't have ED...only 54 year old dudes like me and thank God for Trimix LOL!

Couple of questions:

1. Have you ever used steroids in a cycle before (AAS use)?
2. You stated you are on no meds whatsoever; correct?
3. Are you under any stress like work or school or working different shifts?
4. Have had a complete blood work done including complete Thyroid, hormones (especially estrogen) and Prolactin tested? If not, you need to get a thorough work up done including a Physical done. There are any number of pathologies that are insidious and ED being one of the early symptoms.

I like that you are trying to fix this with an NO stack but I would want to eliminate all other possible cause first.

 

I like the information you provide here. Very simple to understand. Thank you.

 

Hi Gene,

Thanks for your reply!

1. No I have never taken steroids
2. Yeah no meds other than the odd pain killer ibuprofen etc
3. Stress could be arguable as this situation can stress me out sometimes also I could get better sleep if Im honest only getting 6-6.5 hrs most nights.
4. I am going to try and book a blood test with my doc next week if possible..I will post results on here if I can..

question - will I require separate blood tests for Thyroid, Prolactin, Total Test, Free Test?, Estrogen or can they be grouped into 1 blood test?

Thanks again

 

To: The Dude.
The information you provided is easy to understand. I like the way you post it.

 

DanJ - These are the labs you need and you need everyone and a Physician who knows how to read and understand the results of each; just know most GP's don't.


Testosterone Total
DHEA-S
Testosterone Bioavailable
Estradiol (“sensitive” assay only)
Testosterone Free
Blood Chemistries
SHBG
CBC
LH/FSH
PSA
Prolactin (if T <150)
DHT

 

I just found this great table summarizing studies done on improving nitric oxide in men with ED.




Source:
http://onlinelibrary.wiley.com/doi/10.1111/bph.12700/full#bph12700-bib-0006

 

Nitric oxide also has a beneficial role in maintaining sperm quality.

 

A couple of bits of info:

1) I discovered that Walmart has an "88 cents" section in the First Aid area. It's helpful to fill out your First Aid drawer with generic stuff like bandaids, etc. But one of the items is a Pill Cutter, so I got one to try out - and it works quite well. Not perfectly - but roughly as well as any of the other ones that cost upwards of $10.

2) I mention that because I find that the thing to try when you get "side effects" from Cialis and Viagra, is take half as much or a quarter as much. Don't do this with prescribed health meds without asking your Doctor first. But with "recreational" meds like Cialis and Viagra, one finds that smaller doses can have the same effect on "wood" but without the headaches, backaches, etc.

3) For example, in my case (everyone's body is different), I find that roughly 3.5mg of generic tadalafil ("Cialis") is the biggest dose that I can take without side effects. So I take that dose twice a day (similar to Gene's first post regimen, but a lower dose). For awhile I was trying 3.5 at bedtime and 2.5 in the morning, BUT one of my discoveries is that the stack works better with a constant even dose - the same dose every time.

 

More studies showing Nitric Oxide production from Beets (in this case, one cup of beetroot juice), increases blood flow and lowers blood pressure - but only as long as it is taken regularly. Once a day was enough, since the effect lasted for 24 hours. Use of either mouthwash or antacid stops the nitric oxide from occurring. See:

http://v6.examinecdn.com/erd/sneakpeek5.pdf

 

Interesting that mouthwash and antacid stops NO from occurring.

 

Interesting that mouthwash and antacid stops NO from occurring.

The mouthwash thing was actually tested and verified in a study, and is mentioned frequently.

The antacid thing I have only seen twice, and I think it is a surmise based on the digestive conversion requiring an acid environment (so that someone who constantly and daily takes a lot of antacid, and neutralizes their stomach acid, will impair the conversion.)

 

Great article by my good buddy Lee Myers

Nitric Oxide Replacement Therapy

 

All good stuff. Unfortunately, Lee seems stuck in the false "low-fat" concept from 1977.

In case anyone is interested in the political (and not scientific) basis of the "low-fat" concept, this half-hour documentary from Australian TV explains it well:

https://vimeo.com/77730824

 

Come on guys!

Some 245 views and just a handful of posts???

I had this same thread on another "HRT" forum I used to Moderate some time ago and that thread is still alive and well even now.

If you want serious, and I mean serious vascularity, supper hard pumps in the gym that seems to last forever, great morning erections and harder longer lasting erections you need to give this stack a try.

I attached a pic of my right forearm taken not that long ago...and this was 8 hours after being in the gym!

I want to hear from you guys that have given this stack a good 30 day trial and post your results here.View attachment 270

I'm not sure what you normally look like but I'd say by the size of that forearm you've been lifting a long time. So I'm not sure if you would look any different without all of the supplements.

 

All good stuff. Unfortunately, Lee seems stuck in the false "low-fat" concept from 1977.

In case anyone is interested in the political (and not scientific) basis of the "low-fat" concept, this half-hour documentary from Australian TV explains it well:

https://vimeo.com/77730824

Dude - I've been reading Lee Meyer for a while and I don't think he advocates a low-fat diet per se, more of a moderate healthy fat paradigm. I myself eat a primarily plant-based diet with moderate fat in the form of fish, nuts, flax/hemp/pumpkin seeds, etc. I get about 8-9 helpings of fruit and plants daily.

Animal based products have a lot lower nutrients-per-calorie benefit than does plant-based stuff and I don't buy all this higher-fat/saturated fat being good for you business - a lot of so called debunking is from journalists who are excellent at writing in a style to persuade people who do not read their material with sufficient skepticism. Let me know when writers such as Taubes and Nina Teicholz perform any clinical studies. Amazon is flooded with books from folks claiming to have found that one True Diet.

 

Real studies of diet would take billions of dollars, because you have to have things controlled so the only difference is the diet.

If you actually read the Taubes and Teicholz books, they are less about advocating a particular diet, as they are about exposing the zero science behind the government's low-fat diet recommendation in 1977. It turned out to be all about politics and business. Nothing has changed.

The half-hour video linked is written by a medical doctor and all the interviews are with medical doctors.

You say: "I don't buy all this higher-fat/saturated fat being good for you business" because you have been surrounded by it all your life ("Heart Attack On A Plate OMG") , but all the evidence against saturated fat is faulty.

You say: "Animal based products have a lot lower nutrients-per-calorie benefit than does plant-based stuff." This is a vast oversimplification of the human body's needs. You have to have a biased idea of "nutrient" to say that.

 

I'm not sure what you normally look like but I'd say by the size of that forearm you've been lifting a long time. So I'm not sure if you would look any different without all of the supplements.

Being vascular has some to do with lifting but nowhere near what this stack will do for you.

Don't believe me?

Try my stack for just 90 days than report back on your results

 

Im 51 years old and in and out of the gym my whole life. Just retired from LE after 30 yrs and went through several surgeries and med issues related to the job. Needless to say I was a physical wreck with pain meds and hard miles on the body! Lol...Gettin old aint for pussies!!
Been on trt just shy of 1 year and added Gene's stack to daily regimine with the exception of cialis. I was in a bad place for last couple years but how I feel now, I wish i felt this good last couple years of work!
In the boner area so to speak, had mild ed on and off even with trt, after the NO stack, leaning out and excersising its amazing how good life is! I attribute alot of sucess to the addition of the NO stack!
Thanks Gene!

 

Just curious Gene. Have you logged any numbers (blood tests, etc) over time that correlate to your stack to show some historical trends?

 

Just curious Gene. Have you logged any numbers (blood tests, etc) over time that correlate to your stack to show some historical trends?

What would I measure in blood work?

This is more subjective results which is where the rubber meets the road anyway.

Just like TRT, if you feel good on your protocol; who cares about the numbers...right?