Fsh

galaxy

Member
I was wondering if there are any benefits besides spermatogenesis for taking FSH assuming cost wasn't an issue. I know there's a large advocacy of taking HCG for testicular volume and back filling upstream hormones, why doesn't the same concern apply with FSH and back filling?
 
I don’t think FSH has any use other than spermatogenesis in men. Not like LH which causes a cascade of hormones and is replaced by HCG when HPT axis is supressed on TRT. I can be wrong but from what I read i come to this conclusion. However fertility is extremely important for most young men on TRT or even men on their 40s that might wanna father a child in the near future. In that case FSH can be extremely important. Long term shutdown of FSH might end up causing damage to Sertori cells in the testicles.
 
Thanks HealthMan. Your story is what got me interested in it to begin with. I'm in my early 30s and am just starting TRT. My current protocol is Androgel 1.62% 4 pumps plus 500 IU HCG pregnyl twice a week. I've had a semen analysis done beforehand and banked some spern as well. The plan is to retest semen in 4 months and see if I need to add fsh or another 500 IU of Hcg/week If there were other benefits though to the fsh asides from fertility, which can potentially be maintained by Hcg, then I'd be interested in taking the fsh to begin with as well.
 
Thanks HealthMan. Your story is what got me interested in it to begin with. I'm in my early 30s and am just starting TRT. My current protocol is Androgel 1.62% 4 pumps plus 500 IU HCG pregnyl twice a week. I've had a semen analysis done beforehand and banked some spern as well. The plan is to retest semen in 4 months and see if I need to add fsh or another 500 IU of Hcg/week If there were other benefits though to the fsh asides from fertility, which can potentially be maintained by Hcg, then I'd be interested in taking the fsh to begin with as well.
Thats a good plan. However make sure to do another semen analysis if the first one comes back somewhat normal. It might take more time to have your spermatogenesis more severely affected because of the exogenous testosterone
 
Right ya makes sense. I'll probably just keep doing sperm banking every 6 months as that kills two birds with one stone. They do the analysis as well as storage for the same price of a doctor's analysis. Thanks for your help on all this.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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