First bloodtest after starting TRT

Coltthedog

New Member
Started on Cypionate approx 8 weeks ago, 70 ml every 3.5 days. My total T shot up from 360 to over 1000. I feel good, but have no libido and my testicles have decreased in size. Is my E2 ratio off or is something else amiss? Thanks in advance.

Testosterone, Total, LC/MS 1003.1 High ng/dL 264.0 - 916.0 02
Free Testosterone(Direct) 22.3 High pg/mL 6.8 - 21.5 02
Estradiol, Sensitive 41.3 High pg/mL 8.0 - 35.0 02


BUN/Creatinine Ratio 13
Sodium, Serum 143
Potassium, Serum 4.4
Chloride, Serum 102
Carbon Dioxide, Total 25
Calcium, Serum 8.9
Protein, Total, Serum 6.4 g
Albumin, Serum 4.1
Globulin, Total 2.3
A/G Ratio 1.8
Bilirubin, Total 1.0
Alkaline Phosphatase, S 64
AST (SGOT) 15
ALT (SGPT) 12

Lipid Panel w/ Chol/HDL Ratio
Cholesterol, Total 153 mg/dL
Triglycerides 63 mg/dL
HDL Cholesterol 45 mg/dL
VLDL Cholesterol Cal 13 mg/dL
LDL Cholesterol Calc 95 mg/dL
T. Chol/HDL Ratio 3.4 r

CBC With Differential/Platelet
WBC 4.6
RBC 5.01 x
Hemoglobin 15.3
Hematocrit 46.5
MCV 93
MCH 30.5 p
MCHC 32.9
RDW 13.6
Platelets 272
Neutrophils 51
Lymphs 32
Monocytes 7
Eos 9
Basos 1
Neutrophils (Absolute) 2.4
Lymphs (Absolute) 1.5
Monocytes(Absolute) 0.3
Eos (Absolute) 0.4
Baso (Absolute) 0.0
Immature Granulocytes 0
Immature Grans (Abs) 0.0


Comp. Metabolic Panel (14)
Glucose, Serum 104 High
BUN 15
Creatinine, Serum 1.15
 
Libido...is that your interest in or wanting to have sex and cannot because of ED, can get an erection but you're not interested or both...can you tell us the difference?

I dont see a problem in your basic hormone profile...an E of ~40 isn't really "high", per se.

Were you fasted for that test...your Glucose was 104
 
Just not much in the way of interest. Still can get erection but have to be prodded unlike in the past. Also some desensitization down there.

In re Glucose, I was not fasting. I had eaten a small bowl of granola at 8:00. Draw was around noon.
 
Those are all great numbers including SHBG. 8 weeks is still very early in the game to expect miracles, it's going to take time. It's taken me almost 6 months to get some energy back and I'm not fatigued as often, still far away from 100 percent though. If you're E2 climbs in the coming months you might be able to just lower your dose a bit and you may not even require an AI if you're lucky, I haven't any need for an AI yet.
 
I think your labs look great, as CW mentioned I would consider adding HCG for testicles. I inject 500iu of HCG every 3 1/2 days for my full testicles and libido. Cialis or tadalafil help should help with penis sensitivity.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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