Dhea combined with ibatumoren for IGF-1increase

The pituitary gland has a natural feedback loop (ceiling effect) that prevents HGH/IGF-1 from getting too high, so you can't overdose on peptides. When this ceiling effect kicks in you feel a head rush, this is that natural feedback looping stunting excess levels.
 
The pituitary gland has a natural feedback loop (ceiling effect) that prevents HGH/IGF-1 from getting too high, so you can't overdose on peptides. When this ceiling effect kicks in you feel a head rush, this is that natural feedback looping stunting excess levels.
nice info. where does the excess go to tho?
 
Why do you want high IGF-1? For muscle building? It takes more than that. Also, ibutamoren can make some guys fat since it increases hunger and most cannot exercise enough to compensate for the extra calories. Make sure you read every post in this long thread:
Oral growth hormone enhancer MK-677 (ibutamoren)

Nelson, if somebody is extremely disciplined and can avoid excess eating. Say only add a little quality calories to add a little lean muscle or even no extra at all. Would you recommend this over the rest of the Growth Hormone boosters? Seems like it is the most effective but has also the biggest trade of with hunger and weight gain...
 
Nelson, if somebody is extremely disciplined and can avoid excess eating. Say only add a little quality calories to add a little lean muscle or even no extra at all. Would you recommend this over the rest of the Growth Hormone boosters? Seems like it is the most effective but has also the biggest trade of with hunger and weight gain...

Yes. No peptide can increase IGF-1 and keep it elevated like ibutamoren. If you control your early morning cravings (assuming you take it at night), you will get great pumps at the gym. Yes, water retention is always an issue like for all GH products. Some people are taking 25 mg every other day or 12.5 mg per day instead of the 25 mg per day dose used in studies.
 
Yes. No peptide can increase IGF-1 and keep it elevated like ibutamoren. If you control your early morning cravings (assuming you take it at night), you will get great pumps at the gym. Yes, water retention is always an issue like for all GH products. Some people are taking 25 mg every other day or 12.5 mg per day instead of the 25 mg per day dose used in studies.

Ok, thanks! I seem to never be hungry and I have never taken anything that increases my appetite. My meals are planned out so if I get hungry my only option will be water or possibly an additional prepped meal. I am going to give this a try. The Doctor ordered from empower and I do believe it is the 25MG per day. Should I try this dose (at night) and then go down as needed?

I am trying to lean up with losing as little muscle and strength as possible. I seem to be stuck at 14-15% body fat. Would love to see how I look at 12% with the same muscle mass. No reason other than just challenging myself.....
 
Curious if anybody noticed the appetite increase day 1... I took 25 MG at bed time last night and my appetite seems normal. Also I assume no carbs probably like an hour or so before the dose?
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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