Advice on my current plan of action (before trt)

valexiz7

Member
heyo! currently 26, weight 154, 6'3''
Im new to this forum and it seems to be the right place to be. so i had my consultation with defy and it went well. I have a pituitary tumor but endocrinologist are clueless on what to do next. defy dr offered trt right away but i decided hcg mono first. i havent tried ANY natural ways to fix. but i was always training with good diet (actually i had an eating disorder) and started to feel meh.
my labs were

(6 hours of sleep before bloodwork and interrupted twice due to frequent urination. its one of my symptoms im guessing low e2)

TSH 1.496 0.55 - 4.78 U/ml

PSA, TOTAL 0.211 0.00 - 4.0 ng/ml
ENDOCRINE EVALUATION
LH <1.9 L 1.5 - 9.3 mIU/ml
ESTRADIOL (E2) 14.0 < 40 pg/mL
DHEA-SULFATE 167.3 34.5 - 568.9 ug/dl
TESTOSTERONE, TOTAL 306 280 - 1100 ng/dl
SEX HORMONE BIND GLOBULIN 48 14.55 - 94.64 nmol/L
TESTOSTERONE, FREE 4.65 1.9 - 27 ng/dl
IGF-1 110 L 150 - 222 ng/mL
FSH 2.2

Plan of action:
HCG monotherapy (injecting 350 daily, 2450 weekly)
dhea 25 mg daily
ibatumoren 12.5 daily (a bit concerned about this one since i have a tumor. dr prescribed me this for gh/igf1 stim. will monitor microadenoma for possible secreting gh adenoma. this one was also weird since my igf1 is low. i forgot to ask him)
retest 2 months to see whats going on.

no clomid due to possible tumor growth while on it and also because of my shbg.

if this protocol does not work then i will move to trt. dr said it would be 62.5 twice weekly with 500 hcg 3 days a week.
what do you guys think?
 
Last edited:
welcome to the forum. I don't know much about HCG monotherapy, but it seems like you are taking a cautious approach. Which is always smart in my opininon. Good luck and keep us posted! I am currently waiting on a MRI scan of my pituitary.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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