Daily dosage and blood work irregularities

Thomas1212

New Member
Hi everyone, first post but have greatly appreciated everyone’s comments on the forum that I have been reading through. I am having some frustration getting my protocol dialed in. Started TRT 1.5 years ago and have been using Testosterone Cypionate and all injections SubQ. Blood work and dosage listed below with follow up questions.



10/2019
40mg x 3 week, total 120 mg per week

Testosterone, total - 1149 ng/d
  • 250 - 1100 ng/dL
Testosterone free - 271.4 pg/mL
  • 35-155 pg/mL
Estradiol - 73 pg/mL
  • < OR = 39 pg/mL
Lowered dose and switched to daily injections mid October 2019 in an attempt to lower E2. New protocol 16mg daily.

12/16/2019 8 weeks on daily protocol

16mg daily, total 112 mg per week

Testosterone, total - 865 ng/dL

Testosterone free - 158 pg/mL

Estradiol - 45 pg/mL
Happy that E2 dropped and thought I was on track to a stable protocol.
4/2020 same daily protocol but higher levels

16mg daily, total 112 mg per week

Testosterone, total - 1114 ng/dL

Testosterone free - 268 pg/mL

Estradiol - 58 pg/mL
Seems like a large increase in Test even though it is the same protocol when blood work was tested in December 2019.

Lowered my dose in an attempt to lower T and E2
6/2020 8 weeks on new daily protocol

14mg daily, total 98 mg per week

Testosterone, total - 545 ng/dL

Testosterone free - 116 pg/mL

Estradiol - <15 pg/mL
All blood work was done with Quest Diagnostics. When on daily protocol blood work was drawn first thing in the morning, fasted and before daily injection.

My current dose of 14mg daily is leaving me not feeling as good as prior and definitely want my testosterone and E2 to be higher. I am having trouble deciding how to proceed.

My blood work seems to increase after a few months of the same dose. I am wondering if keeping my dose of 14mg daily for a few more months will give my body time to stabilize and potentially increase to desired levels. Has anyone else need months for blood work to stabilize? Seems like waiting 6-8 weeks is not giving me to same results that I get after 4 months of the same dose. For past year and a half my doctor keeps changing my dose but my body keeps fluctuating making it hard to get it dialed in. I am still on 14mg daily and will get blood work done again beginning of August. If it is low still I am going to try 15mg daily and hope that is the perfect dose for me.
Any and all suggestions are greatly appreciated. Thank you in advance.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
4
Guests online
372
Total visitors
376

Latest posts

Back
Top