Consultation or Advice for supervision

macj19

New Member
Male 22 years old. I have been treated with TRT for a little over a year now after being diagnosed with secondary hypogonadism and pituitary failure. I regularly get blood work done through my general practitioner but the clinic that provides the treatment has not asked nor seen those results in many months. I have already reduced the original dosage they put me on (250mg 1x/week) to 160mg/week (split into two semi-weekly doses) following a blood test that had testosterone at an abnormally high level.
I'm wondering if there's any resources or outlets I can use for consultation or guidance for the continuation of this treatment. I feel as if I've been navigating this by myself and without any professional expertise (I read and consume hours of studies and medical advice online many days a week to mitigate this).
I'm still experiencing fatigue, low libido, and muscle discomfort and have been throughout this process and would like to know if there is an error I have been making in my conduct. Additionally, I want to do this in the healthiest way possible and continuing on without professional medical supervision cannot be the way to do that.
Any and all help or advice or tips is enourmously appreciated.
 
Defy Medical offers consults and treatment while also offering consults only to overseas patients.

100 mg per week is enough to get the majority of men to mid normal or high normal ranges for Total T and Free T.

Abnormally high testosterone can be as bad as not enough, especially if you have other medical problems.
 
If 100/week put me in a "normal to high normal" range (we'll call it 5-800), is there a reason possibly that the higher doses are not wielding results that lower doses would?
 
is there a reason possibly that the higher doses are not wielding results that lower doses would?
This depends on your genetics, some men feel best closer to midrange while others feel better higher.

100 mg per week isn’t a low dosage, it’s about average.

The muscle discomfort comment suggests you may have something else going on, in addition to secondary hypogonadism.
 

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⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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